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Open field (animal test)

Developed by Calvin S. Hall, the open field test (OFT) is an experimental test used to assay general locomotor activity levels, anxiety, and willingness to explore in animals (usually rodents) in scientific research. However, the extent to which behavior in the open field measures anxiety is controversial. The open field test can be used to assess memory…

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Open field (animal test)

Nodes21
Edges20
Triples9
Avg. degree1.9
Density0.095238
Components1

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anxiety field animal open test models used frequency also center different rodent movement results levels behavior assess memory object experimental

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
ratsinstance ofConceptAnimals0.80text
mice display a natural aversion to brightly lit open areasinstance ofConceptAnimals0.80text
5-HT-1A partial agonistsinstance ofNewer drugs0.80text
selective serotonin reuptake inhibitorsinstance ofNewer drugs0.80text
which have also been proven to treat anxietyinstance ofNewer drugs0.80text
show inconsistent results in this test.Due to the idiopathic nature of anxietyinstance ofNewer drugs0.80text
animal models have flaws that cannot be controlledinstance ofNewer drugs0.80text
the elevated plus mazeinstance ofBecause of this it is better to do the open field test in conjunction with other tests0.80text
light-dark box test.Different results can be obtained depending on the strain of the animalinstance ofBecause of this it is better to do the open field test in conjunction with other tests0.80text

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