Dynamin-like 120 kDa protein

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Interactions

Adenonucleotide transporters ATP synthase CHCHD3 Mitofilin Prohibitin

6 related topics

Clinical significance

Optic atrophy type 1 Dominant optic atrophy (DOA)Ophthalmoplegia Parkinson's disease Antisense oligonucleotide

5 related topics

Structure

Intermembrane space Outer mitochondrial membrane Poison exon

3 related topics

Function

Cytochrome c Reactive oxygen species SLC25A

3 related topics

Key facts & relationships

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3.6.5.5: ↗
Aliases: OPA1, MGM1, NPG, NTG, largeG, Optic atrophy 1, BERHS, MTDPS14, mitochondrial dynamin like GTPase, OPA1 mitochondrial dynamin like GTPase
Band: 3q29 · 16 B2|16 20.65 cM
Bgee: Achilles tendon · endothelial cell · secondary oocyte · lateral nuclear group of thalamus · Brodmann area 23
BioGPS: More reference expression data
Chr.: Chromosome 3 (human) · Chromosome 16 (mouse)

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Overview

Structure

Function

Clinical significance

Optic atrophy type 1 Optic neuropathy
Dominant optic atrophy (DOA) Kjer's optic neuropathy
Ophthalmoplegia Ophthalmoparesis
Parkinson's disease
Antisense oligonucleotide Antisense therapy

Interactions

Adenonucleotide transporters Adenonucleotide transporter?action=edit&redlink=1
ATP synthase
CHCHD3 CHCHD3?action=edit&redlink=1
Mitofilin IMMT
Prohibitin
SAMM50

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Map overview Semantic statistics

Nodes27

Edges26

Triples125

Avg. degree1.93

Density0.074074

Components1

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Dynamin-like 120 kDa protein

Top relations

Gene ontology · 63

Dynamin-like 120 kDa protein → ageing, apoptotic process, axon cytoplasm, axonal transport of mitochondrion, calcium import into the mitochondrion, cardiolipin binding, cellular response to glucose stimulus, cellular response to hypoxia, cellular response to L-glutamate, cellular senescence, cochlea development, cytoplasm, cytosol, dendrite, dynamin family protein polymerization involved in mitochondrial fission, extrinsic component of mitochondrial inner membrane, GTP binding, GTP metabolic process, GTPase activity, hydrolase activity

Bgee · 20

Dynamin-like 120 kDa protein → Achilles tendon, Brodmann area 23, dorsal striatum, endothelial cell, lateral nuclear group of thalamus, medial vestibular nucleus, middle temporal gyrus, monocyte, myocardium of ventricle, nucleus accumbens, olfactory tubercle, pontine nuclei, rectum, Region I of hippocampus proper, right ventricle, secondary oocyte, subiculum, substantia nigra, superior frontal gyrus, temporal lobe

RNA expression pattern · 20

Band · 2

Dynamin-like 120 kDa protein → 16 B2|16 20.65 cM, 3q29

Chr. · 2

Dynamin-like 120 kDa protein → Chromosome 16 (mouse), Chromosome 3 (human)

End · 2

Dynamin-like 120 kDa protein → 193,697,811 bp, 29,473,702 bp

3.6.5.5 · 1

Dynamin-like 120 kDa protein → ↗

Aliases · 1

Dynamin-like 120 kDa protein → OPA1, MGM1, NPG, NTG, largeG, Optic atrophy 1, BERHS, MTDPS14, mitochondrial dynamin like GTPase, OPA1 mitochondrial dynamin like GTPase

BioGPS · 1

Dynamin-like 120 kDa protein → More reference expression data

Databases · 1

Dynamin-like 120 kDa protein → NCBI: entry; OMA: entry

Important terminology Word statistics

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Important terminology

mitochondrial opa1 gene protein bp fusion chr cristae human band optic atrophy leading chromosome membrane structure mutations loss oligomerization inner

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
Dynamin-like 120 kDa protein	3.6.5.5	↗	1.00	infobox
Dynamin-like 120 kDa protein	Aliases	OPA1, MGM1, NPG, NTG, largeG, Optic atrophy 1, BERHS, MTDPS14, mitochondrial dynamin like GTPase, OPA1 mitochondrial dynamin like GTPase	1.00	infobox
Dynamin-like 120 kDa protein	Band	3q29	1.00	infobox
Dynamin-like 120 kDa protein	Band	16 B2\|16 20.65 cM	1.00	infobox
Dynamin-like 120 kDa protein	Bgee	Achilles tendon	1.00	infobox
Dynamin-like 120 kDa protein	Bgee	endothelial cell	1.00	infobox
Dynamin-like 120 kDa protein	Bgee	secondary oocyte	1.00	infobox
Dynamin-like 120 kDa protein	Bgee	lateral nuclear group of thalamus	1.00	infobox
Dynamin-like 120 kDa protein	Bgee	Brodmann area 23	1.00	infobox
Dynamin-like 120 kDa protein	Bgee	middle temporal gyrus	1.00	infobox
Dynamin-like 120 kDa protein	Bgee	right ventricle	1.00	infobox
Dynamin-like 120 kDa protein	Bgee	monocyte	1.00	infobox
Dynamin-like 120 kDa protein	Bgee	rectum	1.00	infobox
Dynamin-like 120 kDa protein	Bgee	superior frontal gyrus	1.00	infobox
Dynamin-like 120 kDa protein	Bgee	dorsal striatum	1.00	infobox
Dynamin-like 120 kDa protein	Bgee	olfactory tubercle	1.00	infobox
Dynamin-like 120 kDa protein	Bgee	nucleus accumbens	1.00	infobox
Dynamin-like 120 kDa protein	Bgee	pontine nuclei	1.00	infobox
Dynamin-like 120 kDa protein	Bgee	temporal lobe	1.00	infobox
Dynamin-like 120 kDa protein	Bgee	Region I of hippocampus proper	1.00	infobox
Dynamin-like 120 kDa protein	Bgee	subiculum	1.00	infobox
Dynamin-like 120 kDa protein	Bgee	medial vestibular nucleus	1.00	infobox
Dynamin-like 120 kDa protein	Bgee	myocardium of ventricle	1.00	infobox
Dynamin-like 120 kDa protein	Bgee	substantia nigra	1.00	infobox
Dynamin-like 120 kDa protein	BioGPS	More reference expression data	1.00	infobox
Dynamin-like 120 kDa protein	Chr.	Chromosome 3 (human)	1.00	infobox
Dynamin-like 120 kDa protein	Chr.	Chromosome 16 (mouse)	1.00	infobox
Dynamin-like 120 kDa protein	Databases	NCBI: entry; OMA: entry	1.00	infobox
Dynamin-like 120 kDa protein	End	193,697,811 bp	1.00	infobox
Dynamin-like 120 kDa protein	End	29,473,702 bp	1.00	infobox

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