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Sodium nitroprusside

Sodium nitroprusside (SNP), sold under the brand name Nitropress among others, is a medication used to lower blood pressure. This may be done if the blood pressure is very high and resulting in symptoms, in certain types of heart failure, and during surgery to decrease bleeding. It is used by continuous injection into a vein. Onset is nearly immediate…

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
C02DD01 (WHO) QC02DD01 (vet)
Bioavailability
100% (intravenous)
CAS Number
13755-38-9
ChEMBL
ChEMBL136478

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Overview

Medical uses

Contraindications

Adverse effects

Interactions

Mechanism of action

Structure and properties

Preparation

History

Other uses

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Map overview Semantic statistics

Sodium nitroprusside

Nodes130
Edges129
Triples87
Avg. degree1.98
Density0.015385
Components1

How this topic connects Entity context

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Sodium nitroprusside

Top relations

related to Mechanism of action · 10
Sodium nitroprusside → As, Cialis, It, Myosin, NO, PDE5, Sodium, The, This, Viagra
related to Medical uses · 9
Sodium nitroprusside → FDA, In, It, Its, MHRA, Nitric, So, Sodium, TGA
related to Contraindications · 7
Sodium nitroprusside → B12, It, Its, Leber's, Patients, Sodium, Some
related to history · 6
Sodium nitroprusside → By, Despite, It, Sodium, US, US FDA
related to Other uses · 6
Sodium nitroprusside → For, In, Iontophoresis, Mössbauer, Pseudomonas, Sodium
Legal status · 4
Sodium nitroprusside → AU: S4 (Prescription only), CA: ℞-only, UK: POM (Prescription only), US: ℞-only
related to Overdose · 3
Sodium nitroprusside → Discontinuing, Due, Treatment
related to Analytical reagent · 2
Sodium nitroprusside → It, Sodium
related to Preparation · 2
Sodium nitroprusside → Alternatively, Sodium
3D model (JSmol) · 1
Sodium nitroprusside → Interactive image

Important terminology Word statistics

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Important terminology

nitroprusside sodium used cyanide effects test also blood amines thiocyanate nitric oxide pressure minutes use reaction due ketones cgmp urine

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Sodium nitroprusside3D model (JSmol)Interactive image1.00infobox
Sodium nitroprussideAHFS/Drugs.comMonograph1.00infobox
Sodium nitroprussideATC codeC02DD01 (WHO) QC02DD01 (vet)1.00infobox
Sodium nitroprussideBioavailability100% (intravenous)1.00infobox
Sodium nitroprussideCAS Number13755-38-91.00infobox
Sodium nitroprussideChEMBLChEMBL1364781.00infobox
Sodium nitroprussideChemSpider211707891.00infobox
Sodium nitroprussideCompTox Dashboard (EPA)DTXSID70411261.00infobox
Sodium nitroprussideDensity1.72 g/cm31.00infobox
Sodium nitroprussideDrugBankDB003251.00infobox
Sodium nitroprussideDuration of action1 to 10 minutes1.00infobox
Sodium nitroprussideECHA InfoCard100.119.1261.00infobox
Sodium nitroprussideElimination half-life<2 minutes (3 days for thiocyanate metabolite)1.00infobox
Sodium nitroprussideExcretionkidney (100%; as thiocyanate)1.00infobox
Sodium nitroprussideFormulaC5FeN6Na2O1.00infobox
Sodium nitroprussideLegal statusAU: S4 (Prescription only)1.00infobox
Sodium nitroprussideLegal statusCA: ℞-only1.00infobox
Sodium nitroprussideLegal statusUK: POM (Prescription only)1.00infobox
Sodium nitroprussideLegal statusUS: ℞-only1.00infobox
Sodium nitroprussideLicense dataUS FDA: Nitroprusside1.00infobox
Sodium nitroprussideMetabolismBy haemoglobin being converted to cyanmethaemoglobin and cyanide ions1.00infobox
Sodium nitroprussideMolar mass261.921 g·mol−11.00infobox
Sodium nitroprussideOnset of actionnearly immediate1.00infobox
Sodium nitroprussideOther namesSNP1.00infobox
Sodium nitroprussidePregnancy categoryAU: C1.00infobox
Sodium nitroprussidePubChem CID119538951.00infobox
Sodium nitroprussideRoutes of administrationIntravenous1.00infobox
Sodium nitroprussideSolubility in water100 mg/mL (20 °C)1.00infobox
Sodium nitroprussideTrade namesNipride, Nitropress, others1.00infobox
Sodium nitroprussideUNIIEAO03PE1TC1.00infobox

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