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NFE2: Measurement, Interactions & Overview

Transcription factor NF-E2 45 kDa subunit is a protein that in humans is encoded by the NFE2 gene.

Language: English [EN]
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NFE2 topic overview

The analysis highlights Measurement, Interactions and Overview as prominent areas in the source structure around NFE2.

Related topics
5
Source areas
2
Connected nodes
7
Extracted relationships
81
Related term clusters
7
Bridge connections
7

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 3 topics
Interactions · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
NFE2, NF-E2, p45, nuclear factor, erythroid 2
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2KZ5
Band
12q13.13 · 15 F3|15 58.62 cM
Bgee
blood · monocyte · granulocyte · trabecular bone · bone marrow
BioGPS
More reference expression data
Chr.
Chromosome 12 (human) · Chromosome 15 (mouse)

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Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Interactions

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How NFE2 connects Entity context

The extracted context around NFE2 shows recurring relationship patterns in the source. For example, NFE2 → blood circulation, blood coagulation, cis-regulatory region sequence-specific DNA binding, cytoplasm, DNA binding, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, hemostasis, multicellular organism development, nucleoplasm, nucleosome disassembly, nucleus, PML body, positive regulation of transcription, DNA-templated, protein binding, protein N-terminus binding, protein-DNA complex, regulation of megakaryocyte differentiation, regulation of transcription by RNA polymerase II, regulation of transcription, DNA-templated Another extracted example is NFE2 → blood, body of femur, bone marrow, bone marrow cell, embryo, fetal liver hematopoietic progenitor cell, granulocyte, human fetus, monocyte, right lung, spleen, testicle, tibiofemoral joint, trabecular bone, upper lobe of left lung, yolk sac. Use these groups to spot repeated connection types before inspecting the individual relationships.

NFE2

Top relations

Gene ontology · 25
NFE2 → blood circulation, blood coagulation, cis-regulatory region sequence-specific DNA binding, cytoplasm, DNA binding, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, hemostasis, multicellular organism development, nucleoplasm, nucleosome disassembly, nucleus, PML body, positive regulation of transcription, DNA-templated, protein binding, protein N-terminus binding, protein-DNA complex, regulation of megakaryocyte differentiation, regulation of transcription by RNA polymerase II, regulation of transcription, DNA-templated
Bgee · 16
NFE2 → blood, body of femur, bone marrow, bone marrow cell, embryo, fetal liver hematopoietic progenitor cell, granulocyte, human fetus, monocyte, right lung, spleen, testicle, tibiofemoral joint, trabecular bone, upper lobe of left lung, yolk sac
RNA expression pattern · 16
NFE2 → blood, body of femur, bone marrow, bone marrow cell, embryo, fetal liver hematopoietic progenitor cell, granulocyte, human fetus, monocyte, right lung, spleen, testicle, tibiofemoral joint, trabecular bone, upper lobe of left lung, yolk sac
Band · 2
NFE2 → 12q13.13, 15 F3|15 58.62 cM
Chr. · 2
NFE2 → Chromosome 12 (human), Chromosome 15 (mouse)
End · 2
NFE2 → 103,166,830 bp, 54,301,015 bp
Aliases · 1
NFE2 → NFE2, NF-E2, p45, nuclear factor, erythroid 2
Available structures · 1
NFE2 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2KZ5
BioGPS · 1
NFE2 → More reference expression data
Databases · 1
NFE2 → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp human chr band gene chromosome 12 protein factor location megakaryocyte mouse transcription nf-e2 external search 301 015 end 54

NFE2 relationships Subject–Predicate–Object triples

TTTA extracted 81 structured relationships around NFE2. Examples in this analysis include NFE2 → Aliases → NFE2, NF-E2, p45, nuclear factor, erythroid 2 and NFE2 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2KZ5. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
NFE2AliasesNFE2, NF-E2, p45, nuclear factor, erythroid 21.00infobox
NFE2Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2KZ51.00infobox
NFE2Band12q13.131.00infobox
NFE2Band15 F3|15 58.62 cM1.00infobox
NFE2Bgeeblood1.00infobox
NFE2Bgeemonocyte1.00infobox
NFE2Bgeegranulocyte1.00infobox
NFE2Bgeetrabecular bone1.00infobox
NFE2Bgeebone marrow1.00infobox
NFE2Bgeebone marrow cell1.00infobox
NFE2Bgeespleen1.00infobox
NFE2Bgeetesticle1.00infobox
NFE2Bgeeright lung1.00infobox
NFE2Bgeeupper lobe of left lung1.00infobox
NFE2Bgeefetal liver hematopoietic progenitor cell1.00infobox
NFE2Bgeetibiofemoral joint1.00infobox
NFE2Bgeehuman fetus1.00infobox
NFE2Bgeeyolk sac1.00infobox
NFE2Bgeeembryo1.00infobox
NFE2Bgeebody of femur1.00infobox
NFE2BioGPSMore reference expression data1.00infobox
NFE2Chr.Chromosome 12 (human)1.00infobox
NFE2Chr.Chromosome 15 (mouse)1.00infobox
NFE2DatabasesNCBI: entry; OMA: entry1.00infobox
NFE2End54,301,015 bp1.00infobox
NFE2End103,166,830 bp1.00infobox
NFE2EnsemblENSG000001234051.00infobox
NFE2Entrez47781.00infobox
NFE2External IDsOMIM: 601490; MGI: 97308; GeneCards: NFE21.00infobox
NFE2Gene location (Human)Gene location (Human)Chr.Chromosome 12 (human)Band12q13.13Start54,292,111 bpEnd54,301,015 bp1.00infobox

Related concept clusters Related term clusters

The concept neighborhoods around NFE2 bring nearby vocabulary together. In this analysis, examples include Protein, Gene and Human. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • gene
    • Location
    • Chromosome
    • Nfe2
    • Bp
    • Chr
    • End
    • F3
    • Human
    • Mouse
    • Nf-e2
    • Search
    • Transcription
  • NFE2
    • Protein
    • Gene
    • Human
    • Search
    • Transcription
    • Location
    • Chromosome
    • Bp
    • Chr
    • External
    • Interactions
    • Links
  • nfe2
    • Protein
    • Gene
    • Human
    • Search
    • Transcription
    • Location
    • Chromosome
    • Bp
    • Chr
    • External
    • Interactions
    • Links
  • protein
    • Nfe2
    • Transcription
    • Gene
    • Encoded
    • Human
    • Humans
    • Subunit
    • Domain
    • End
    • F3
    • Megakaryocyte
    • Mouse
  • creb-binding protein
    • Nfe2
    • Transcription
    • Gene
    • Encoded
    • Human
    • Humans
    • Subunit
    • Domain
    • End
    • F3
    • Megakaryocyte
    • Mouse
  • megakaryocyte
    • Production
    • Domain
    • End
    • F3
    • Mouse
    • Search
    • Transcription
    • Location
    • Protein
    • Band
    • Chromosome
    • Nfe2
  • interactions
    • External
    • Links
    • Reading
    • References
    • Nf-e2
    • Search
    • Location
    • Chromosome
    • Nfe2
    • Bp
    • Chr
    • Human

Connections between topic areas Semantic bridges

For NFE2, one of the stronger structural bridges in this analysis connects NFE2 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
NFE2 — Overview · splits 4 ⟂ 4
NFE2 — Interactions · splits 5 ⟂ 3

Map overview Semantic statistics

NFE2

Nodes8
Edges7
Triples81
Avg. degree1.75
Density0.25
Components1

Source & methodology

TTTA analyzes the structure around NFE2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — NFE2 · EN edition · Analysis: TopicsToTalkAbout

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