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NDUFA2

NADH dehydrogenase 1 alpha subcomplex subunit 2 is a protein that in humans is encoded by the NDUFA2 gene. The NDUFA2 protein is a subunit of NADH dehydrogenase (ubiquinone), which is located in the mitochondrial inner membrane and is the largest of the five complexes of the electron transport chain. Mutations in the NDUFA2 gene are associated with…

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Aliases
NDUFA2, B8, CD14, CIB8, NADH:ubiquinone oxidoreductase subunit A2, MC1DN13
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1S3A
Band
5q31.3 · 18|18 B2
Bgee
biceps brachii · right ventricle · Skeletal muscle tissue of biceps brachii · apex of heart · triceps brachii muscle
BioGPS
More reference expression data
Chr.
Chromosome 5 (human) · Chromosome 18 (mouse)

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NDUFA2

Nodes31
Edges30
Triples102
Avg. degree1.94
Density0.064516
Components1

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NDUFA2

Top relations

Bgee · 20
NDUFA2 → aortic valve, apex of heart, ascending aorta, biceps brachii, body of tongue, condyle, facial motor nucleus, fossa, intercostal muscle, left ventricle, medullary collecting duct, mucosa of transverse colon, Paneth cell, renal corpuscle, right kidney, right ventricle, Skeletal muscle tissue of biceps brachii, thoracic diaphragm, triceps brachii muscle, vastus lateralis muscle
RNA expression pattern · 20
NDUFA2 → aortic valve, apex of heart, ascending aorta, biceps brachii, body of tongue, condyle, facial motor nucleus, fossa, intercostal muscle, left ventricle, medullary collecting duct, mucosa of transverse colon, Paneth cell, renal corpuscle, right kidney, right ventricle, Skeletal muscle tissue of biceps brachii, thoracic diaphragm, triceps brachii muscle, vastus lateralis muscle
Gene ontology · 10
NDUFA2 → blastocyst hatching, membrane, mitochondrial electron transport, NADH to ubiquinone, mitochondrial inner membrane, mitochondrial membranes, mitochondrial respiratory chain complex I, mitochondrial respiratory chain complex I assembly, mitochondrion, NADH dehydrogenase (ubiquinone) activity, respirasome
related to Function · 10
NDUFA2 → Complex, CoQ, CoQH2, Fe-S, FMN, FMNH2, Initially, NADH, Q10, The
related to Structure · 8
NDUFA2 → C-terminal, Complex, It, L-shaped, N-terminal, NADH, The, The NDUFA2
related to Clinical significance · 6
NDUFA2 → Complex, Leigh's, Mutations, One, The NDUFA2, This
related to Interactions · 3
NDUFA2 → Complex, NADH, This
Band · 2
NDUFA2 → 18|18 B2, 5q31.3
Chr. · 2
NDUFA2 → Chromosome 18 (mouse), Chromosome 5 (human)
End · 2
NDUFA2 → 140,647,771 bp, 36,877,610 bp

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Important terminology

nadh gene ubiquinone complex protein bp subunit human dehydrogenase chr band chromosome mitochondrial membrane inner chain hydrophobic redox assembly location

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
NDUFA2AliasesNDUFA2, B8, CD14, CIB8, NADH:ubiquinone oxidoreductase subunit A2, MC1DN131.00infobox
NDUFA2Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1S3A1.00infobox
NDUFA2Band5q31.31.00infobox
NDUFA2Band18|18 B21.00infobox
NDUFA2Bgeebiceps brachii1.00infobox
NDUFA2Bgeeright ventricle1.00infobox
NDUFA2BgeeSkeletal muscle tissue of biceps brachii1.00infobox
NDUFA2Bgeeapex of heart1.00infobox
NDUFA2Bgeetriceps brachii muscle1.00infobox
NDUFA2Bgeemucosa of transverse colon1.00infobox
NDUFA2Bgeevastus lateralis muscle1.00infobox
NDUFA2Bgeethoracic diaphragm1.00infobox
NDUFA2Bgeeleft ventricle1.00infobox
NDUFA2Bgeebody of tongue1.00infobox
NDUFA2Bgeeaortic valve1.00infobox
NDUFA2Bgeefossa1.00infobox
NDUFA2Bgeefacial motor nucleus1.00infobox
NDUFA2Bgeeascending aorta1.00infobox
NDUFA2Bgeemedullary collecting duct1.00infobox
NDUFA2Bgeecondyle1.00infobox
NDUFA2Bgeerenal corpuscle1.00infobox
NDUFA2Bgeeintercostal muscle1.00infobox
NDUFA2Bgeeright kidney1.00infobox
NDUFA2BgeePaneth cell1.00infobox
NDUFA2BioGPSMore reference expression data1.00infobox
NDUFA2Chr.Chromosome 5 (human)1.00infobox
NDUFA2Chr.Chromosome 18 (mouse)1.00infobox
NDUFA2DatabasesNCBI: entry; OMA: entry1.00infobox
NDUFA2End140,647,771 bp1.00infobox
NDUFA2End36,877,610 bp1.00infobox

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