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NAB2: Function, Pathology & Overview

NGFI-A-binding protein 2 also known as EGR-1-binding protein 2 or melanoma-associated delayed early response protein (MADER) is a protein that in humans is encoded by the NAB2 gene.

Language: English [EN]
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NAB2 topic overview

The analysis highlights Function, Pathology and Overview as prominent areas in the source structure around NAB2.

Related topics
9
Source areas
3
Connected nodes
12
Extracted relationships
80
Related term clusters
7
Bridge connections
12

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 5 topics
Overview · 2 topics
Pathology · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
NAB2, MADER, NGFI-A binding protein 2
Band
12q13.3 · 10 D3|10 74.6 cM
Bgee
right hemisphere of cerebellum · left ovary · right ovary · popliteal artery · canal of the cervix
BioGPS
More reference expression data
Chr.
Chromosome 12 (human) · Chromosome 10 (mouse)
Databases
NCBI: entry; OMA: entry

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Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Pathology

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How NAB2 connects Entity context

The extracted context around NAB2 shows recurring relationship patterns in the source. For example, NAB2 → anterior pituitary, body of uterus, calvaria, canal of the cervix, cerebellar vermis, dentate gyrus of hippocampal formation granule cell, Descending thoracic aorta, external carotid artery, Gonadal ridge, internal carotid artery, left ovary, left uterine tube, lip, lobe of cerebellum, olfactory tubercle, popliteal artery, right hemisphere of cerebellum, right ovary, superior frontal gyrus, tibial arteries Another extracted example is NAB2 → cell population proliferation, endochondral ossification, identical protein binding, myelination, negative regulation of transcription by RNA polymerase III, negative regulation of transcription, DNA-templated, nervous system development, nucleus, positive regulation of tau-protein kinase activity, protein binding, regulation of epidermis development, regulation of transcription, DNA-templated, Schwann cell differentiation, transcription coregulator activity, transcription corepressor activity, transcription factor binding, transcription, DNA-templated. Use these groups to spot repeated connection types before inspecting the individual relationships.

NAB2

Top relations

Bgee · 20
NAB2 → anterior pituitary, body of uterus, calvaria, canal of the cervix, cerebellar vermis, dentate gyrus of hippocampal formation granule cell, Descending thoracic aorta, external carotid artery, Gonadal ridge, internal carotid artery, left ovary, left uterine tube, lip, lobe of cerebellum, olfactory tubercle, popliteal artery, right hemisphere of cerebellum, right ovary, superior frontal gyrus, tibial arteries
RNA expression pattern · 20
NAB2 → anterior pituitary, body of uterus, calvaria, canal of the cervix, cerebellar vermis, dentate gyrus of hippocampal formation granule cell, Descending thoracic aorta, external carotid artery, Gonadal ridge, internal carotid artery, left ovary, left uterine tube, lip, lobe of cerebellum, olfactory tubercle, popliteal artery, right hemisphere of cerebellum, right ovary, superior frontal gyrus, tibial arteries
Gene ontology · 17
NAB2 → cell population proliferation, endochondral ossification, identical protein binding, myelination, negative regulation of transcription by RNA polymerase III, negative regulation of transcription, DNA-templated, nervous system development, nucleus, positive regulation of tau-protein kinase activity, protein binding, regulation of epidermis development, regulation of transcription, DNA-templated, Schwann cell differentiation, transcription coregulator activity, transcription corepressor activity, transcription factor binding, transcription, DNA-templated
related to Pathology · 3
NAB2 → NGFI-A, Recurrent, STAT6
Band · 2
NAB2 → 10 D3|10 74.6 cM, 12q13.3
Chr. · 2
NAB2 → Chromosome 10 (mouse), Chromosome 12 (human)
End · 2
NAB2 → 127,504,437 bp, 57,095,476 bp
Aliases · 1
NAB2 → NAB2, MADER, NGFI-A binding protein 2
BioGPS · 1
NAB2 → More reference expression data
Databases · 1
NAB2 → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp gene chr protein human band chromosome 12 binding location function transcription mouse ngfi-a mader response encoded external 095 476

NAB2 relationships Subject–Predicate–Object triples

TTTA extracted 80 structured relationships around NAB2. Examples in this analysis include NAB2 → Aliases → NAB2, MADER, NGFI-A binding protein 2 and NAB2 → Band → 12q13.3. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
NAB2AliasesNAB2, MADER, NGFI-A binding protein 21.00infobox
NAB2Band12q13.31.00infobox
NAB2Band10 D3|10 74.6 cM1.00infobox
NAB2Bgeeright hemisphere of cerebellum1.00infobox
NAB2Bgeeleft ovary1.00infobox
NAB2Bgeeright ovary1.00infobox
NAB2Bgeepopliteal artery1.00infobox
NAB2Bgeecanal of the cervix1.00infobox
NAB2Bgeetibial arteries1.00infobox
NAB2Bgeeleft uterine tube1.00infobox
NAB2BgeeDescending thoracic aorta1.00infobox
NAB2Bgeebody of uterus1.00infobox
NAB2Bgeeanterior pituitary1.00infobox
NAB2Bgeecerebellar vermis1.00infobox
NAB2Bgeelobe of cerebellum1.00infobox
NAB2Bgeelip1.00infobox
NAB2Bgeecalvaria1.00infobox
NAB2Bgeeexternal carotid artery1.00infobox
NAB2Bgeeinternal carotid artery1.00infobox
NAB2BgeeGonadal ridge1.00infobox
NAB2Bgeesuperior frontal gyrus1.00infobox
NAB2Bgeeolfactory tubercle1.00infobox
NAB2Bgeedentate gyrus of hippocampal formation granule cell1.00infobox
NAB2BioGPSMore reference expression data1.00infobox
NAB2Chr.Chromosome 12 (human)1.00infobox
NAB2Chr.Chromosome 10 (mouse)1.00infobox
NAB2DatabasesNCBI: entry; OMA: entry1.00infobox
NAB2End57,095,476 bp1.00infobox
NAB2End127,504,437 bp1.00infobox
NAB2EnsemblENSG000001668861.00infobox

Related concept clusters Related term clusters

The concept neighborhoods around NAB2 bring nearby vocabulary together. In this analysis, examples include Protein, Binding and Ngfi-a. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • NAB2
    • Protein
    • Binding
    • Ngfi-a
    • Gene
    • External
    • Function
    • Response
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
  • nab2
    • Protein
    • Binding
    • Ngfi-a
    • Gene
    • External
    • Function
    • Response
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
  • gene
    • Location
    • Chromosome
    • Human
    • Nab2
    • Bp
    • Chr
    • D3
    • End
    • External
    • Function
    • Mader
    • Mouse
  • function
    • External
    • Binding
    • Location
    • Ngfi-a
    • Chromosome
    • Gene
    • Human
    • Nab2
    • Nucleus
    • Bp
    • Chr
    • Protein
  • protein
    • Binding
    • Ngfi-a
    • External
    • Function
    • Response
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Nucleus
    • 12q13
  • egr
    • Nab
    • Proteins
    • Repress
    • Transcription
    • Nucleus
    • End
    • External
    • Function
    • Mouse
    • Response
    • Two
    • Location
  • transcription
    • Two

Connections between topic areas Semantic bridges

For NAB2, one of the stronger structural bridges in this analysis connects NAB2 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
NAB2 — Function · splits 7 ⟂ 6
NAB2 — Overview · splits 10 ⟂ 3
NAB2 — Pathology · splits 10 ⟂ 3

Map overview Semantic statistics

NAB2

Nodes13
Edges12
Triples80
Avg. degree1.85
Density0.153846
Components1

Source & methodology

TTTA analyzes the structure around NAB2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Pathology & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — NAB2 · EN edition · Analysis: TopicsToTalkAbout

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