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ABCC1

Multidrug resistance-associated protein 1 (MRP1) is a protein that in humans is encoded by the ABCC1 gene.

Research, Clinical significance & Animal studies

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7.6.2.2
7.6.2.3
Aliases
ABCC1, ABC29, ABCC, GS-X, MRP, MRP1, ATP binding cassette subfamily C member 1, DFNA77
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2CBZ, 4C3Z
Band
16p13.11 · 16|16 A1
Bgee
stromal cell of endometrium · ascending aorta · gastric mucosa · left lobe of thyroid gland · right lobe of thyroid gland

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Function

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Clinical significance

Animal studies

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Map overview Semantic statistics

ABCC1

Nodes18
Edges17
Triples160
Avg. degree1.89
Density0.111111
Components1

How this topic connects Entity context

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ABCC1

Top relations

Gene ontology · 33
ABCC1 → ABC-type glutathione S-conjugate transporter activity, ABC-type vitamin B12 transporter activity, ABC-type xenobiotic transporter activity, ATP binding, ATPase activity, ATPase-coupled inorganic anion transmembrane transporter activity, ATPase-coupled intramembrane lipid transporter activity, ATPase-coupled transmembrane transporter activity, basolateral plasma membrane, cell chemotaxis, cobalamin metabolic process, cobalamin transport, extracellular exosome, glutathione transmembrane transport, glutathione transmembrane transporter activity, hydrolase activity, integral component of membrane, integral component of plasma membrane, leukotriene metabolic process, membrane
Bgee · 19
ABCC1 → ankle, ascending aorta, bone marrow cell, conjunctival fornix, Descending thoracic aorta, endothelial cell of lymphatic vessel, gastric mucosa, hair follicle, left lobe of thyroid gland, olfactory epithelium, prostate, retinal pigment epithelium, right lobe of thyroid gland, skeletal muscle tissue, skin of external ear, spleen, stroma of bone marrow, stromal cell of endometrium, tunica media of zone of aorta
RNA expression pattern · 19
ABCC1 → ankle, ascending aorta, bone marrow cell, conjunctival fornix, Descending thoracic aorta, endothelial cell of lymphatic vessel, gastric mucosa, hair follicle, left lobe of thyroid gland, olfactory epithelium, prostate, retinal pigment epithelium, right lobe of thyroid gland, skeletal muscle tissue, skin of external ear, spleen, stroma of bone marrow, stromal cell of endometrium, tunica media of zone of aorta
related to Effect of polymorphisms · 16
ABCC1 → Carriers, Certain, CF, Chinese, COPD, Examples, G-260C, G2168A, If, In, Individuals, On, Polymorphisms, UTR, UTR G3361A, UTR T866A
related to Structure · 14
ABCC1 → ABC, Asian, ATP, ATP-binding, Caucasian, Each, In, NBD1, NBD2, Polymorphisms, SNP, The, There, This
related to Animal studies · 10
ABCC1 → ABBC1, AD, Alzheimer's, APP-tg, Because, Furthermore, In, In ABBC1, John's, St
related to External links · 8
ABCC1 → Human ABCC1, Medicine, Medicine Medical Subject Headings, MeSH, National Library, This, UCSC Genome Browser, United States National Library
related to Alzheimer's disease · 6
ABCC1 → Alzheimer's, As, Due, One, The, The ATP-binding
related to Genomic location and tissue expression · 5
ABCC1 → ATP-binding, It, The, The ABCC1, While ABCC1
related to Role in cancer · 3
ABCC1 → In, Similar, The ABCC1

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Important terminology

gene protein found polymorphisms transporter human bp disease cancer chr band location binding chromosome 16 alzheimer's also cassette nucleotide expression

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
ABCC17.6.2.21.00infobox
ABCC17.6.2.31.00infobox
ABCC1AliasesABCC1, ABC29, ABCC, GS-X, MRP, MRP1, ATP binding cassette subfamily C member 1, DFNA771.00infobox
ABCC1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2CBZ, 4C3Z1.00infobox
ABCC1Band16p13.111.00infobox
ABCC1Band16|16 A11.00infobox
ABCC1Bgeestromal cell of endometrium1.00infobox
ABCC1Bgeeascending aorta1.00infobox
ABCC1Bgeegastric mucosa1.00infobox
ABCC1Bgeeleft lobe of thyroid gland1.00infobox
ABCC1Bgeeright lobe of thyroid gland1.00infobox
ABCC1BgeeDescending thoracic aorta1.00infobox
ABCC1Bgeeprostate1.00infobox
ABCC1Bgeebone marrow cell1.00infobox
ABCC1Bgeeskeletal muscle tissue1.00infobox
ABCC1Bgeespleen1.00infobox
ABCC1Bgeestroma of bone marrow1.00infobox
ABCC1Bgeeskin of external ear1.00infobox
ABCC1Bgeeendothelial cell of lymphatic vessel1.00infobox
ABCC1Bgeeolfactory epithelium1.00infobox
ABCC1Bgeeconjunctival fornix1.00infobox
ABCC1Bgeeankle1.00infobox
ABCC1Bgeeretinal pigment epithelium1.00infobox
ABCC1Bgeetunica media of zone of aorta1.00infobox
ABCC1Bgeehair follicle1.00infobox
ABCC1BioGPSMore reference expression data1.00infobox
ABCC1Chr.Chromosome 16 (human)1.00infobox
ABCC1Chr.Chromosome 16 (mouse)1.00infobox
ABCC1DatabasesNCBI: entry; OMA: entry1.00infobox
ABCC1End16,143,257 bp1.00infobox

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