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MPGES-2

Microsomal prostaglandin E synthase-2 (mPGES-2) or Prostaglandin E synthase 2 is an enzyme that in humans encoded by the PTGES2 gene located on chromosome 9. The protein encoded by this gene is a membrane-associated prostaglandin E synthase, which catalyzes the conversion of prostaglandin H2 to prostaglandin E2. This protein also has been shown to…

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5.3.99.3
↗
Aliases
PTGES2, C9orf15, GBF-1, GBF1, PGES2, mPGES-2, prostaglandin E synthase 2
Band
9q34.11 · 2|2 B
Bgee
apex of heart · gastrocnemius muscle · mucosa of transverse colon · left ventricle · right auricle of heart
BioGPS
n/a
Chr.
Chromosome 9 (human) · Chromosome 2 (mouse)

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Map overview Semantic statistics

MPGES-2

Nodes27
Edges26
Triples91
Avg. degree1.93
Density0.074074
Components1

How this topic connects Entity context

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MPGES-2

Top relations

Gene ontology · 31
MPGES-2 → azurophil granule lumen, cell redox homeostasis, cyclooxygenase pathway, cytoplasm, cytosol, DNA binding, electron transfer activity, electron transport chain, extracellular region, fatty acid biosynthetic process, fatty acid metabolic process, glutathione binding, Golgi apparatus, Golgi membrane, heme binding, integral component of membrane, isomerase activity, lipid metabolism, lyase activity, membrane
Bgee · 19
MPGES-2 → anterior cingulate cortex, apex of heart, brown adipose tissue, dentate gyrus of hippocampal formation granule cell, gastrocnemius muscle, granulocyte, interventricular septum, left adrenal gland, left ventricle, masseter muscle, mucosa of transverse colon, muscle of thigh, neural layer of retina, prefrontal cortex, proximal tubule, right auricle of heart, right frontal lobe, right kidney, soleus muscle
RNA expression pattern · 19
MPGES-2 → anterior cingulate cortex, apex of heart, brown adipose tissue, dentate gyrus of hippocampal formation granule cell, gastrocnemius muscle, granulocyte, interventricular septum, left adrenal gland, left ventricle, masseter muscle, mucosa of transverse colon, muscle of thigh, neural layer of retina, prefrontal cortex, proximal tubule, right auricle of heart, right frontal lobe, right kidney, soleus muscle
Band · 2
MPGES-2 → 2|2 B, 9q34.11
Chr. · 2
MPGES-2 → Chromosome 2 (mouse), Chromosome 9 (human)
End · 2
MPGES-2 → 128,128,462 bp, 32,295,784 bp
5.3.99.3 · 1
MPGES-2 → ↗
Aliases · 1
MPGES-2 → PTGES2, C9orf15, GBF-1, GBF1, PGES2, mPGES-2, prostaglandin E synthase 2
BioGPS · 1
MPGES-2 → n/a
Databases · 1
MPGES-2 → NCBI: entry; OMA: entry

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Important terminology

prostaglandin gene synthase protein bp ptges2 human chromosome chr band shown encoded transcription location 128 ptge2 activity mouse cell lipid

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
MPGES-25.3.99.3↗1.00infobox
MPGES-2AliasesPTGES2, C9orf15, GBF-1, GBF1, PGES2, mPGES-2, prostaglandin E synthase 21.00infobox
MPGES-2Band9q34.111.00infobox
MPGES-2Band2|2 B1.00infobox
MPGES-2Bgeeapex of heart1.00infobox
MPGES-2Bgeegastrocnemius muscle1.00infobox
MPGES-2Bgeemucosa of transverse colon1.00infobox
MPGES-2Bgeeleft ventricle1.00infobox
MPGES-2Bgeeright auricle of heart1.00infobox
MPGES-2Bgeeright frontal lobe1.00infobox
MPGES-2Bgeeprefrontal cortex1.00infobox
MPGES-2Bgeeanterior cingulate cortex1.00infobox
MPGES-2Bgeemuscle of thigh1.00infobox
MPGES-2Bgeeleft adrenal gland1.00infobox
MPGES-2Bgeeright kidney1.00infobox
MPGES-2Bgeeproximal tubule1.00infobox
MPGES-2Bgeebrown adipose tissue1.00infobox
MPGES-2Bgeegranulocyte1.00infobox
MPGES-2Bgeeneural layer of retina1.00infobox
MPGES-2Bgeesoleus muscle1.00infobox
MPGES-2Bgeemasseter muscle1.00infobox
MPGES-2Bgeedentate gyrus of hippocampal formation granule cell1.00infobox
MPGES-2Bgeeinterventricular septum1.00infobox
MPGES-2BioGPSn/a1.00infobox
MPGES-2Chr.Chromosome 9 (human)1.00infobox
MPGES-2Chr.Chromosome 2 (mouse)1.00infobox
MPGES-2DatabasesNCBI: entry; OMA: entry1.00infobox
MPGES-2End128,128,462 bp1.00infobox
MPGES-2End32,295,784 bp1.00infobox
MPGES-2EnsemblENSG000001483341.00infobox

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