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Missing heritability problem

In genetics, the missing heritability problem refers to a difference between heritability estimates obtained from early genome-wide association studies (GWAS) and heritability estimates from twin and family data across many physical and mental traits, including diseases, behaviors, and other phenotypes.

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Missing heritability problem

Nodes20
Edges19
Triples35
Avg. degree1.9
Density0.1
Components1

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Missing heritability problem

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related to Dilemma · 26
Missing heritability problem → Among, Each, For, GCTA, Genetic, GWAS, GWASes, If, IQ, LP, Much, Several, SNP, SNPs, Standard, The, Therefore, These, This, Thus
related to Discovery · 6
Missing heritability problem → For, GWASes, SNPs, The, The Human Genome Project, While

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studies variants heritability genetic missing gwas small traits candidate-gene trait genes sample effects due many genetics large would height sizes

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SubjectPredicateObjectConfidenceSrc
candidate-gene studies which used small samples with limited genetic sequencing to focus on specific genes believed to be involvedinstance ofwould soon be mapped and pinned down to specific genes and their genetic variants by methods0.80text
examining single-nucleotide polymorphismsinstance ofwould soon be mapped and pinned down to specific genes and their genetic variants by methods0.80text
80instance ofDilemmaStandard genetics methods have long estimated large heritabilities0.80text
Missing heritability problemrelated to DilemmaStandard0.60section
Missing heritability problemrelated to DilemmaIQ0.60section
Missing heritability problemrelated to DilemmaIf0.60section
Missing heritability problemrelated to DilemmaSeveral0.60section
Missing heritability problemrelated to DilemmaTwin0.60section
Missing heritability problemrelated to DilemmaTherefore0.60section
Missing heritability problemrelated to DilemmaFor0.60section
Missing heritability problemrelated to DilemmaGenetic0.60section
Missing heritability problemrelated to DilemmaAmong0.60section

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