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Methenamine, also known as hexamine or hexamethylenetetramine and sold under the brand names Hiprex, Urex, and Urotropin among others, is a urinary tract antiseptic and antibacterial medication which is used in the prevention of recurrent urinary tract infections (UTIs). It is not an antibiotic, and unlike antibiotics, has no risk of bacterial…
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| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Methenamine | 3D model (JSmol) | Interactive image | 1.00 | infobox |
| Methenamine | ATC code | J01XX05 (WHO) G04BX17 (with sodium salicylate) | 1.00 | infobox |
| Methenamine | Bioavailability | High (≥70%) | 1.00 | infobox |
| Methenamine | CAS Number | 100-97-0 Y 5714-73-8 (hippurate) 587-23-5 (mandelate) | 1.00 | infobox |
| Methenamine | ChEBI | CHEBI:6824 Y | 1.00 | infobox |
| Methenamine | ChEMBL | ChEMBL1201270 Y | 1.00 | infobox |
| Methenamine | ChemSpider | 3959 Y | 1.00 | infobox |
| Methenamine | Drug class | Antiseptic; Antibacterial | 1.00 | infobox |
| Methenamine | DrugBank | DB06799 | 1.00 | infobox |
| Methenamine | Elimination half-life | 2–6 hours | 1.00 | infobox |
| Methenamine | Excretion | Urine: 70–90% unchanged within 24 hours | 1.00 | infobox |
| Methenamine | Formula | C6H12N4 | 1.00 | infobox |
| Methenamine | KEGG | D00393 Y | 1.00 | infobox |
| Methenamine | Metabolism | Hydrolysis in acidic urine | 1.00 | infobox |
| Methenamine | Metabolites | • Formaldehyde • Ammonia • Formic acid | 1.00 | infobox |
| Methenamine | Molar mass | 140.190 g·mol−1 | 1.00 | infobox |
| Methenamine | Onset of action | ≤30 minutes | 1.00 | infobox |
| Methenamine | Other names | Hexamethylenetetramine; HMTA; Hexamine; Hexamethylenamine; Hexamethyleneamine; Metenamine; Urometine; Hippramine; E-239; R-657; 1,3,5,7-Tetraazaadamantane | 1.00 | infobox |
| Methenamine | Pronunciation | meh-THEH-na-meen | 1.00 | infobox |
| Methenamine | Protein binding | Unknown | 1.00 | infobox |
| Methenamine | PubChem CID | 4101 | 1.00 | infobox |
| Methenamine | PubChem SID | 310264893 | 1.00 | infobox |
| Methenamine | Routes of administration | Oral, topical | 1.00 | infobox |
| Methenamine | Trade names | Antihydral, Hiprex, Urex, Urotropin, others | 1.00 | infobox |
| Methenamine | UNII | J50OIX95QV | 1.00 | infobox |
| Methenamine | is a | prodrug of formaldehyde in acidic urine | 0.90 | text |
| Methenamine | is a | simple cyclized hydrocarbon and is similar in structure to adamantane.Methenamine was discovered in 1859 and was first introduced for medical use as a urinary antiseptic in 1895 | 0.90 | text |
| Methenamine | is a | cation and hippuric acid or mandelic acid is the anion | 0.90 | text |
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