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MESP2: Function, Clinical significance & Overview

Mesoderm posterior protein 2 (MESP2), also known as class C basic helix-loop-helix protein 6 (bHLHc6), is a protein that in humans is encoded by the MESP2 gene.

Language: English [EN]
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MESP2 topic overview

The analysis highlights Function, Clinical significance and Overview as prominent areas in the source structure around MESP2.

Related topics
8
Source areas
3
Connected nodes
11
Extracted relationships
78
Concept neighborhoods
10
Bridge connections
11

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 5 topics
Overview · 2 topics
Clinical significance · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
MESP2, SCDO2, bHLHc6, mesoderm posterior bHLH transcription factor 2
Band
15q26.1 · 7 D2|7 45.18 cM
Bgee
gonad · testicle · buccal mucosa cell · lower lobe of lung · mucosa of transverse colon
BioGPS
n/a
Chr.
Chromosome 15 (human) · Chromosome 7 (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Clinical significance

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How MESP2 connects Entity context

The extracted context around MESP2 shows recurring relationship patterns in the source. For example, MESP2 → Brodmann area 9, buccal mucosa cell, embryo, female urethra, gonad, lower lobe of lung, male urethra, morula, mucosa of transverse colon, nucleus accumbens, palpebral conjunctiva, prefrontal cortex, primary oocyte, secondary oocyte, skin of thigh, spermatocyte, testicle, urethra, zygote Another extracted example is MESP2 → DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, embryonic pattern specification, heart morphogenesis, mesoderm formation, multicellular organism development, Notch signaling pathway, nucleus, positive regulation of transcription by RNA polymerase II, protein dimerization activity, regulation of transcription by RNA polymerase II, regulation of transcription, DNA-templated, RNA polymerase II cis-regulatory region sequence-specific DNA binding, somitogenesis, transcription by RNA polymerase II, transcription, DNA-templated. Use these groups to spot repeated connection types before inspecting the individual relationships.

MESP2

Top relations

Bgee · 19
MESP2 → Brodmann area 9, buccal mucosa cell, embryo, female urethra, gonad, lower lobe of lung, male urethra, morula, mucosa of transverse colon, nucleus accumbens, palpebral conjunctiva, prefrontal cortex, primary oocyte, secondary oocyte, skin of thigh, spermatocyte, testicle, urethra, zygote
RNA expression pattern · 19
MESP2 → Brodmann area 9, buccal mucosa cell, embryo, female urethra, gonad, lower lobe of lung, male urethra, morula, mucosa of transverse colon, nucleus accumbens, palpebral conjunctiva, prefrontal cortex, primary oocyte, secondary oocyte, skin of thigh, spermatocyte, testicle, urethra, zygote
Gene ontology · 18
MESP2 → DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, embryonic pattern specification, heart morphogenesis, mesoderm formation, multicellular organism development, Notch signaling pathway, nucleus, positive regulation of transcription by RNA polymerase II, protein dimerization activity, regulation of transcription by RNA polymerase II, regulation of transcription, DNA-templated, RNA polymerase II cis-regulatory region sequence-specific DNA binding, somitogenesis, transcription by RNA polymerase II, transcription, DNA-templated
Band · 2
MESP2 → 15q26.1, 7 D2|7 45.18 cM
Chr. · 2
MESP2 → Chromosome 15 (human), Chromosome 7 (mouse)
End · 2
MESP2 → 79,463,187 bp, 89,778,754 bp
related to Clinical significance · 2
MESP2 → Mutations, Spondylocostal
Aliases · 1
MESP2 → MESP2, SCDO2, bHLHc6, mesoderm posterior bHLH transcription factor 2
BioGPS · 1
MESP2 → n/a
Databases · 1
MESP2 → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene bp mesoderm chr human band chromosome 15 location transcription protein mouse formation posterior bhlhc6 function also factor 778 754

MESP2 relationships Subject–Predicate–Object triples

TTTA extracted 78 structured relationships around MESP2. Examples in this analysis include MESP2 → Aliases → MESP2, SCDO2, bHLHc6, mesoderm posterior bHLH transcription factor 2 and MESP2 → Band → 15q26.1. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
MESP2AliasesMESP2, SCDO2, bHLHc6, mesoderm posterior bHLH transcription factor 21.00infobox
MESP2Band15q26.11.00infobox
MESP2Band7 D2|7 45.18 cM1.00infobox
MESP2Bgeegonad1.00infobox
MESP2Bgeetesticle1.00infobox
MESP2Bgeebuccal mucosa cell1.00infobox
MESP2Bgeelower lobe of lung1.00infobox
MESP2Bgeemucosa of transverse colon1.00infobox
MESP2Bgeeskin of thigh1.00infobox
MESP2Bgeeprefrontal cortex1.00infobox
MESP2Bgeepalpebral conjunctiva1.00infobox
MESP2BgeeBrodmann area 91.00infobox
MESP2Bgeenucleus accumbens1.00infobox
MESP2Bgeezygote1.00infobox
MESP2Bgeesecondary oocyte1.00infobox
MESP2Bgeeprimary oocyte1.00infobox
MESP2Bgeeurethra1.00infobox
MESP2Bgeefemale urethra1.00infobox
MESP2Bgeemale urethra1.00infobox
MESP2Bgeeembryo1.00infobox
MESP2Bgeespermatocyte1.00infobox
MESP2Bgeemorula1.00infobox
MESP2BioGPSn/a1.00infobox
MESP2Chr.Chromosome 15 (human)1.00infobox
MESP2Chr.Chromosome 7 (mouse)1.00infobox
MESP2DatabasesNCBI: entry; OMA: entry1.00infobox
MESP2End89,778,754 bp1.00infobox
MESP2End79,463,187 bp1.00infobox
MESP2EnsemblENSG000001880951.00infobox
MESP2Entrez1458731.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around MESP2 bring nearby vocabulary together. In this analysis, examples include Bhlh, Factor and Function. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • gene
    • Mesoderm
    • Mesp2
    • Formation
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Bhlh
    • D2
    • End
    • Expressed
  • bhlh
    • Factor
    • Function
    • Transcription
    • Location
    • Chromosome
    • Human
    • Mesp2
    • Notch
    • Signaling
    • Bp
    • Chr
    • Mesoderm
  • transcription factors
    • Bhlh
    • Factor
    • Function
    • Location
    • Chromosome
    • Human
    • Mesp2
    • Notch
    • Signaling
    • Bp
    • Chr
    • Mesoderm
  • mesoderm
    • Gene
    • Formation
    • Mesp2
    • Also
    • Bhlh
    • Bhlhc6
    • Expressed
    • Factor
    • Function
    • Plays
    • Posterior
    • Protein
  • function
    • Bhlh
    • Factor
    • Transcription
    • Location
    • Chromosome
    • Human
    • Mesp2
    • Notch
    • Signaling
    • Bp
    • Chr
    • Mesoderm
  • MESP2
    • Bhlh
    • Factor
    • Function
    • Posterior
    • Protein
    • Transcription
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Notch
  • mesp2
    • Bhlh
    • Factor
    • Function
    • Posterior
    • Protein
    • Transcription
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Notch
  • protein
    • Notch
    • Signaling
    • Plays
    • Role
    • Somites
    • Transcription

Connections between topic areas Semantic bridges

For MESP2, one of the stronger structural bridges in this analysis connects MESP2 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
MESP2Function · splits 6 ⟂ 6
MESP2Overview · splits 9 ⟂ 3

Map overview Semantic statistics

MESP2

Nodes12
Edges11
Triples78
Avg. degree1.83
Density0.166667
Components1

Source & methodology

TTTA analyzes the structure around MESP2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Clinical significance & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — MESP2 · EN edition · Analysis: TopicsToTalkAbout

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