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Mesna: Applications, Medical uses & Names

Mesna, sold under the brand name Mesnex among others, is a medication used in those taking cyclophosphamide or ifosfamide to decrease the risk of bleeding from the bladder. It is used either by mouth or injection into a vein.

Language: English [EN]
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Mesna topic overview

The analysis highlights Applications, Medical uses and Names as prominent areas in the source structure around Mesna.

Related topics
20
Source areas
4
Connected nodes
24
Extracted relationships
44
Concept neighborhoods
13
Bridge connections
24

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 9 topics
Medical uses · 8 topics
Names · 2 topics
Administration · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
R05CB05 (WHO) V03AF01 (WHO)
Bioavailability
45–79% (by mouth)
CAS Number
19767-45-4 N
ChEMBL
ChEMBL975 Y

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Administration

Names

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Mesna connects Entity context

The extracted context around Mesna shows recurring relationship patterns in the source. For example, Mesna → It, IV, The, The IV Another extracted example is Mesna → BC Cancer AgencyNIH/MedlinePlus, Medicine Medical Subject Headings, MeSH, National Library. Use these groups to spot repeated connection types before inspecting the individual relationships.

Mesna

Top relations

related to Administration · 4
Mesna → It, IV, The, The IV
related to External links · 4
Mesna → BC Cancer AgencyNIH/MedlinePlus, Medicine Medical Subject Headings, MeSH, National Library
Legal status · 3
Mesna → AU: S4 (Prescription only), UK: POM (Prescription only), US: ℞-only
related to Chemotherapy adjuvant · 3
Mesna → Michael, These, This
related to Mechanism of action · 3
Mesna → Michael, The, This
related to Other · 3
Mesna → Mistabron, Mistabronco, Outside North America
is a · 2
Mesna → organosulfur compound, water-soluble compound with antioxidant properties
3D model (JSmol) · 1
Mesna → Interactive image
AHFS/Drugs.com · 1
Mesna → Monograph
ATC code · 1
Mesna → R05CB05 (WHO) V03AF01 (WHO)

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

cyclophosphamide ifosfamide used administration metabolites chemotherapy medical name mouth urotoxic side effects include use acrolein pregnancy also reaction compounds iv

Mesna relationships Subject–Predicate–Object triples

TTTA extracted 44 structured relationships around Mesna. Examples in this analysis include Mesna → 3D model (JSmol) → Interactive image and Mesna → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Mesna3D model (JSmol)Interactive image1.00infobox
MesnaAHFS/Drugs.comMonograph1.00infobox
MesnaATC codeR05CB05 (WHO) V03AF01 (WHO)1.00infobox
MesnaBioavailability45–79% (by mouth)1.00infobox
MesnaCAS Number19767-45-4 N1.00infobox
MesnaChEMBLChEMBL975 Y1.00infobox
MesnaChemSpider27663 Y1.00infobox
MesnaCompTox Dashboard (EPA)DTXSID10208091.00infobox
MesnaDrugBankDB09110 Y1.00infobox
MesnaECHA InfoCard100.039.3361.00infobox
MesnaElimination half-life0.36–8.3 hours1.00infobox
MesnaExcretionkidney1.00infobox
MesnaFormulaC2H5NaO3S21.00infobox
MesnaKEGGD01459 Y1.00infobox
MesnaLegal statusAU: S4 (Prescription only)1.00infobox
MesnaLegal statusUK: POM (Prescription only)1.00infobox
MesnaLegal statusUS: ℞-only1.00infobox
MesnaMetabolismOxidised in circulation1.00infobox
MesnaMolar mass164.17 g·mol−11.00infobox
MesnaPregnancy categoryAU: B11.00infobox
MesnaPronunciation/ˈmɛznə/1.00infobox
MesnaPubChem CID297691.00infobox
MesnaRoutes of administrationBy mouth, intravenous1.00infobox
MesnaUNIINR7O1405Q91.00infobox
Mesnais aorganosulfur compound0.90text
Mesnais awater-soluble compound with antioxidant properties0.90text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Mesna bring nearby vocabulary together. In this analysis, examples include Cyclophosphamide, Ifosfamide and Used. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Mesna
    • Cyclophosphamide
    • Ifosfamide
    • Used
    • Administration
    • Also
    • Chemotherapy
    • Iv
    • Oral
    • Bioavailability
    • Bladder
    • Cancer
    • Compound
  • mesna
    • Cyclophosphamide
    • Ifosfamide
    • Used
    • Administration
    • Also
    • Chemotherapy
    • Iv
    • Oral
    • Bioavailability
    • Bladder
    • Cancer
    • Compound
  • cyclophosphamide
    • Ifosfamide
    • Given
    • Name
    • Mesna
    • Used
    • Agents
    • Bioavailability
    • Bladder
    • Cancer
    • Compound
    • Excretion
    • Infusions
  • ifosfamide
    • Given
    • Name
    • Mesna
    • Used
    • Agents
    • Bioavailability
    • Bladder
    • Cancer
    • Compound
    • Excretion
    • Infusions
    • Intravenous
  • administration
    • Chemotherapy
    • Urotoxic
    • Addition
    • Bioavailability
    • Bladder
    • Cancer
    • Excretion
    • Intravenous
    • May
    • Michael
    • Na
    • Patient
  • medical uses
    • Bioavailability
    • Cancer
    • Excretion
    • Intravenous
    • Na
    • Patient
    • Pregnancy
    • Sodium
    • Use
    • Administration
    • Also
    • Chemotherapy
  • bleeding from the bladder
    • Addition
    • Mesnex
    • Michael
    • Sold
    • Acrolein
    • Administration
    • Chemotherapy
    • Name
    • Urotoxic
    • Cyclophosphamide
    • Ifosfamide
    • Metabolites
  • by mouth
    • Used
    • Bioavailability
    • Cancer
    • Excretion
    • Intravenous
    • Na
    • Patient
    • Pregnancy
    • Sodium
    • Administration
    • Also
    • Chemotherapy

Connections between topic areas Semantic bridges

For Mesna, one of the stronger structural bridges in this analysis connects Mesna with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
MesnaOverview · splits 15 ⟂ 10
MesnaMedical uses · splits 16 ⟂ 9
MesnaNames · splits 22 ⟂ 3

Map overview Semantic statistics

Mesna

Nodes25
Edges24
Triples44
Avg. degree1.92
Density0.08
Components1

Source & methodology

TTTA analyzes the structure around Mesna to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Applications, Medical uses & Names, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Mesna · EN edition · Analysis: TopicsToTalkAbout

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