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Lysin

Lysins, also known as endolysins or murein hydrolases, are hydrolytic enzymes produced by host bacteria when infected with bacteriophages in order to cleave the cell wall during the final stage of the lytic cycle to release the viral particles. Lysins are highly evolved enzymes that are able to target one of the five bonds in peptidoglycan (murein), the…

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BRENDA
enzyme data
CAS no.
9001-63-2
EC no.
3.2.1.17
ExPASy
NiceZyme view
Gene Ontology
AmiGO / QuickGO
KEGG
enzyme entry

Topics to explore

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Overview

Structure

Mode of action

Efficacy

Immune response

Antimicrobial use

Advanced semantic analysis

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Map overview Semantic statistics

Lysin

Nodes42
Edges41
Triples60
Avg. degree1.95
Density0.047619
Components1

How this topic connects Entity context

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Lysin

Top relations

related to Catalytic domain · 9
Lysin → D-glutaminyl-L-lysine, EC3, Endo-β-N-acetylglucosaminidase, Endoglycosidase, EndopeptidaseN-acetylmuramoyl-L-alanine, Functionally, N-acetylmuramidase, T7-like, The
related to Efficacy · 8
Lysin → Gram-negative, Gram-positive, However, OBPgp279, Phage, Regarding, Similarly, While
related to Mode of action · 8
Lysin → All, However, IgG, In, Loessner, Since, The, Theoretically
related to Structure · 8
Lysin → All, C-terminal, Double-stranded DNA, For, N-terminal, PlyC, PlyCA, PlyCB
related to Antimicrobial use · 5
Lysin → Lysins, Phage, PlyC, Streptococcus, The
related to Immune response · 4
Lysin → Cpl-1, Nonetheless, One, Unlike
BRENDA · 1
Lysin → enzyme data
CAS no. · 1
Lysin → 9001-63-2
EC no. · 1
Lysin → 3.2.1.17
ExPASy · 1
Lysin → NiceZyme view

Important terminology Word statistics

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Important terminology

lysins cell phage peptidoglycan catalytic wall bacterial domain bacteria resistance domains also high bonds membrane enzymes proteins cell-binding pdb two

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
LysinBRENDAenzyme data1.00infobox
LysinCAS no.9001-63-21.00infobox
LysinEC no.3.2.1.171.00infobox
LysinExPASyNiceZyme view1.00infobox
LysinGene OntologyAmiGO / QuickGO1.00infobox
LysinKEGGenzyme entry1.00infobox
LysinMetaCycmetabolic pathway1.00infobox
LysinNCBIproteins1.00infobox
LysinPDB structuresRCSB PDB PDBe PDBsum1.00infobox
LysinPMCarticles1.00infobox
LysinPubMedarticles1.00infobox
LysinRheareactions1.00infobox
LysinSearchSearchPMCarticlesPubMedarticlesNCBIproteins1.00infobox

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    Min side: 3
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