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Holins are a diverse group of small proteins produced by dsDNA bacteriophages in order to trigger and control the degradation of the host's cell wall at the end of the lytic cycle. Holins form pores in the host's cell membrane, allowing lysins to reach and degrade peptidoglycan, a component of bacterial cell walls. Holins have been shown to regulate the…
The analysis highlights Classification and Overview as prominent areas in the source structure around Holin.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around Holin shows recurring relationship patterns in the source. For example, Holin → Archaea, Bacteria, Bacteriology, BBA, Bhaskara, Bin, Biochimica, Biomedical Applications, Biomembranes, Biophysica Acta, Bläsi, Characterization, Du, Eukaryotes, FEMS Microbiology Reviews, Hengan, Holins, JB, Ji, Jianhe Another extracted example is Holin → According, IHolin, IIHolin, IIIHolin, IVHolin, Transporter Classification Database, VHolin, VIHolin, VII. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
holins class families protein phage bacterial proteins membrane doi pmid bacteriophage ii iii gene lysins include 10 form periplasm diverse
TTTA extracted 54 structured relationships around Holin. Examples in this analysis include the S protein of lambdoid phage 21 act by forming heptameric channels that depolarize the bacterial membrane → instance of → pinholins and Holin → related to Further reading → Reddy. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| the S protein of lambdoid phage 21 act by forming heptameric channels that depolarize the bacterial membrane | instance of | pinholins | 0.80 | text |
| Holin | related to Further reading | Reddy | 0.60 | section |
| Holin | related to Further reading | Bhaskara | 0.60 | section |
| Holin | related to Further reading | Saier Jr | 0.60 | section |
| Holin | related to Further reading | Milton | 0.60 | section |
| Holin | related to Further reading | Topological | 0.60 | section |
| Holin | related to Further reading | Biochimica | 0.60 | section |
| Holin | related to Further reading | Biophysica Acta | 0.60 | section |
| Holin | related to Further reading | BBA | 0.60 | section |
| Holin | related to Further reading | Biomembranes | 0.60 | section |
| Holin | related to Further reading | PMC | 0.60 | section |
| Holin | related to Further reading | PMID | 0.60 | section |
The concept neighborhoods around Holin bring nearby vocabulary together. In this analysis, examples include Superfamilies, Protein and Iii. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Holin, one of the stronger structural bridges in this analysis connects Holin with Classification. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Holin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Classification & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Holin · EN edition · Analysis: TopicsToTalkAbout