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Lead compound

A lead compound (/ˈliːd/, i.e., a "leading" compound; not to be confused with various compounds of the element lead) in drug discovery is a chemical compound that has pharma­co­logical or biological activity likely to be therapeutically useful, but may never­the­less have suboptimal structure that requires modification to fit better to the target; lead…

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Discovering lead compounds

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Lead compound

Nodes27
Edges26
Triples9
Avg. degree1.93
Density0.074074
Components1

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Lead compound

Top relations

related to Development of a lead compound · 7
Lead compound → Chemicals, Lead, Lipinski's, Once, Other, Pfizer, This
related to Discovery of a drugable target · 2
Lead compound → Before, Drug

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Important terminology

lead compounds target chemical discovery drug may pharma co compound development biological structure modification also drug-like selectivity rational design must

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Lead compoundrelated to Development of a lead compoundLead0.60section
Lead compoundrelated to Development of a lead compoundChemicals0.60section
Lead compoundrelated to Development of a lead compoundOnce0.60section
Lead compoundrelated to Development of a lead compoundThis0.60section
Lead compoundrelated to Development of a lead compoundLipinski's0.60section
Lead compoundrelated to Development of a lead compoundPfizer0.60section
Lead compoundrelated to Development of a lead compoundOther0.60section
Lead compoundrelated to Discovery of a drugable targetBefore0.60section
Lead compoundrelated to Discovery of a drugable targetDrug0.60section

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    Min side: 3
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