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Chlorproguanil/dapsone (sold commercially as Lapdap) was a fixed dose antimalarial combination containing chlorproguanil and dapsone, which act synergistically against malaria. The drug was withdrawn in 2008 following increasing evidence of toxicity in the form of haemolysis occurring in patients with G6PD deficiency.
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chlorproguanil dapsone antimalarial drug withdrawn malaria haemolysis sold commercially lapdap fixed dose combination containing act synergistically 2008 following increasing evidence
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Chlorproguanil/dapsone | CAS Number | 209665-78-1 | 1.00 | infobox |
| Chlorproguanil/dapsone | Chlorproguanil | Antimalarial drug | 1.00 | infobox |
| Chlorproguanil/dapsone | Dapsone | Antibiotic | 1.00 | infobox |
| Chlorproguanil/dapsone | Legal status | Withdrawn | 1.00 | infobox |
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