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Kinetic resolution

In organic chemistry, kinetic resolution is a means of differentiating two enantiomers in a racemic mixture. In kinetic resolution, two enantiomers react with different reaction rates in a chemical reaction with a chiral catalyst or reagent, resulting in an enantioenriched sample of the less reactive enantiomer. As opposed to chiral resolution, kinetic…

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Overview

History

Theory

Practicality

Reactions utilizing synthetic reagents

Enzymatic reactions

Dynamic kinetic resolution

Parallel kinetic resolution

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Map overview Semantic statistics

Kinetic resolution

Nodes89
Edges88
Triples147
Avg. degree1.98
Density0.022472
Components1

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Kinetic resolution

Top relations

related to Further reading · 19
Kinetic resolution → Asymmetric Synthesis, David Ebner Stoltz Group, Dynamic Kinetic Resolutions, Erik Alexanian Supergroup Meeting, Jake Wiener LinkDynamic Kinetic, June, LinkDynamic Kinetic Resolution, LinkKinetic Resolution, Literature Seminar, MacMillan Group Meeting, March, Powerful Approach, Practical Applications, Resolution, Resolutions, Synthesis, UT Southwestern Presentation, Valerie Keller, Year Seminar November
related to Parallel kinetic resolution · 14
Kinetic resolution → CBS, For, Fu's, Highly, In, Mortierella, NRRL, One, PKR, PKR's, Thus, Using, With PKR, Yoshito Kishi
related to Acylations · 12
Kinetic resolution → As, Aspergillus, Degussa's, Especially, In, Lipase, Lipases, On, Pseudomonas, PSL, Strecker, The
related to Epoxide openings · 11
Kinetic resolution → Due, HKR, In, Jacobsen, Jacobsen's, Sharpless, Shi, The, Utilizing, While, Yields
related to Epoxidations and dihydroxylations · 9
Kinetic resolution → Additionally, Barry Sharpless, However, Reaction, Sharpless, Shi, The Sharpless, This, While
related to history · 9
Kinetic resolution → After, Kinetic, Louis Pasteur, Marckwald, McKenzie, Penicillium, The, This, With
related to Enzymatic dynamic kinetic resolutions · 8
Kinetic resolution → Another, As, CALB, Candida, However, PSL, When, Without
related to Noyori asymmetric hydrogenation · 8
Kinetic resolution → As, BINAP, Noyori, Ru, Solvent, The, The Noyori, X2
related to Acylation reactions · 7
Kinetic resolution → DMAP, Gregory Fu, However, In, Initial, This, With
related to Dynamic kinetic resolution · 7
Kinetic resolution → Curtin-Hammett, DKR, Dynamic, For, The, Then, This

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Important terminology

kinetic resolution catalyst ee racemic alcohols shown yield material reaction chiral product starting enantiomers yields enantiomer use enantioenriched also highly

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Kinetic resolutionis ameans of differentiating two enantiomers in a racemic mixture0.90text
Kinetic resolutionrelated to Acylation reactionsGregory Fu0.60section
Kinetic resolutionrelated to Acylation reactionsDMAP0.60section
Kinetic resolutionrelated to Acylation reactionsInitial0.60section
Kinetic resolutionrelated to Acylation reactionsHowever0.60section
Kinetic resolutionrelated to Acylation reactionsWith0.60section
Kinetic resolutionrelated to Acylation reactionsThis0.60section
Kinetic resolutionrelated to Acylation reactionsIn0.60section
Kinetic resolutionrelated to AcylationsAs0.60section
Kinetic resolutionrelated to AcylationsEspecially0.60section
Kinetic resolutionrelated to AcylationsOn0.60section
Kinetic resolutionrelated to AcylationsDegussa's0.60section

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