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Corey–Itsuno reduction

The Corey–Itsuno reduction, also known as the Corey–Bakshi–Shibata (CBS) reduction, is a chemical reaction in which a prochiral ketone is enantioselectively reduced to produce the corresponding chiral, non-racemic alcohol. The oxazaborolidine reagent which mediates the enantioselective reduction of ketones was previously developed by the laboratory of…

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StereoselectiveChemoselectiveEnoneYnoneHeteroatoms
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OxazaborolidineScope
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Corey–Link reactionKanamienamides
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Corey–Itsuno reduction

Nodes22
Edges21
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Avg. degree1.91
Density0.090909
Components1

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reduction cbs reaction borane catalyst ketone ketones oxazaborolidine chiral also asymmetric corey bh3 shown enantioselectivity itsuno scope first use reducing

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