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Iroquois-class homeodomain protein IRX-3, also known as Iroquois homeobox protein 3, is a protein that in humans is encoded by the IRX3 gene.
The analysis highlights Clinical significance, Function and Discovery and name as prominent areas in the source structure around IRX3.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
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The extracted context around IRX3 shows recurring relationship patterns in the source. For example, IRX3 → abdominal wall, bronchial epithelial cell, calvaria, epithelium of lactiferous gland, gingival epithelium, human penis, lacrimal gland, lactiferous duct, lactiferous gland, left lung lobe, maxillary prominence, myocardium of left ventricle, nipple, right lung, right lung lobe, right ventricle, skin of arm, trachea, vestibular membrane of cochlear duct, vulva Another extracted example is IRX3 → Additionally, Brugada, Embryonically, Gja1-encoded Connexin-43, Gja5-encoded Connexin-40, Iroquois, Members, MN, NKX2-2, Nkx6, Purkinje, QRS, Sonic, Specifically, The Irx3, V0, V1, V2, V3, VCS. Use these groups to spot repeated connection types before inspecting the individual relationships.
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expression human fto bp gene iroquois chr band expressed also chromosome 16 location function genes obesity mouse homeobox family protein
TTTA extracted 115 structured relationships around IRX3. Examples in this analysis include IRX3 → Aliases → IRX3, IRX-1, IRXB1, iroquois homeobox 3 and IRX3 → Band → 16q12.2. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| IRX3 | Aliases | IRX3, IRX-1, IRXB1, iroquois homeobox 3 | 1.00 | infobox |
| IRX3 | Band | 16q12.2 | 1.00 | infobox |
| IRX3 | Band | 8 C5|8 44.55 cM | 1.00 | infobox |
| IRX3 | Bgee | nipple | 1.00 | infobox |
| IRX3 | Bgee | human penis | 1.00 | infobox |
| IRX3 | Bgee | skin of arm | 1.00 | infobox |
| IRX3 | Bgee | myocardium of left ventricle | 1.00 | infobox |
| IRX3 | Bgee | bronchial epithelial cell | 1.00 | infobox |
| IRX3 | Bgee | vulva | 1.00 | infobox |
| IRX3 | Bgee | epithelium of lactiferous gland | 1.00 | infobox |
| IRX3 | Bgee | lactiferous duct | 1.00 | infobox |
| IRX3 | Bgee | trachea | 1.00 | infobox |
| IRX3 | Bgee | gingival epithelium | 1.00 | infobox |
| IRX3 | Bgee | lacrimal gland | 1.00 | infobox |
| IRX3 | Bgee | left lung lobe | 1.00 | infobox |
| IRX3 | Bgee | maxillary prominence | 1.00 | infobox |
| IRX3 | Bgee | calvaria | 1.00 | infobox |
| IRX3 | Bgee | abdominal wall | 1.00 | infobox |
| IRX3 | Bgee | vestibular membrane of cochlear duct | 1.00 | infobox |
| IRX3 | Bgee | lactiferous gland | 1.00 | infobox |
| IRX3 | Bgee | right lung | 1.00 | infobox |
| IRX3 | Bgee | right lung lobe | 1.00 | infobox |
| IRX3 | Bgee | right ventricle | 1.00 | infobox |
| IRX3 | BioGPS | n/a | 1.00 | infobox |
| IRX3 | Chr. | Chromosome 16 (human) | 1.00 | infobox |
| IRX3 | Chr. | Chromosome 8 (mouse) | 1.00 | infobox |
| IRX3 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| IRX3 | End | 54,286,787 bp | 1.00 | infobox |
| IRX3 | End | 92,528,695 bp | 1.00 | infobox |
| IRX3 | Ensembl | ENSG00000177508 | 1.00 | infobox |
The concept neighborhoods around IRX3 bring nearby vocabulary together. In this analysis, examples include Expression, Fto and Human. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For IRX3, one of the stronger structural bridges in this analysis connects IRX3 with Clinical significance. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around IRX3 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Clinical significance, Function & Discovery and name, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — IRX3 · EN edition · Analysis: TopicsToTalkAbout