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Explore the main themes, entities and connections around FNDC5. Start with the topic map, then use the sections below for research and deeper semantic analysis.
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Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.
History
Fibronectin type III domainsPeroxisomalPeptide hormoneKnock-out miceBeneficial cognitive effects of physical exercise
6 related topics
Biosynthesis and secretion
8 related topics
Function
7 related topics
Overview
11 related topics
Key facts & relationships
High-confidence facts extracted from structured source data. Use them as anchors for further research.
- Aliases
- FNDC5, FRCP2, irisin, Irisin, fibronectin type III domain containing 5
- Available structures
- Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4LSD
- Band
- 1p35.1 · 4|4 D2.2
- Bgee
- Skeletal muscle tissue of biceps brachii · muscle of thigh · Skeletal muscle tissue of rectus abdominis · vastus lateralis muscle · right hemisphere of cerebellum
- BioGPS
- n/a
- Chr.
- Chromosome 1 (human) · Chromosome 4 (mouse)
Topics to explore
A structured outline of related entities, concepts and subtopics. Open any item to build a new map centered on it.Browse the full topic structure. Each item opens a new analysis centered on that subject.
Overview
- Glycoprotein
- Gene
- Greek Ancient Greece
- Iris Iris (mythology)
- Membrane protein
- Thermogenin
- Expression Expression (genetics)
- Fat cells Adipocytes
- MRNA
- White fat White adipose tissue
- Brown fat Brown adipose tissue
History
- Fibronectin type III domains Fibronectin type III domain
- Peroxisomal Peroxisome
- Peptide hormone
- Knock-out mice
- Beneficial cognitive effects of physical exercise Neurobiological effects of physical exercise
- Alzheimer's disease
Biosynthesis and secretion
Function
- PGC-1alpha PPARGC1A
- Myokine
- ERRα Estrogen-related receptor alpha
- BDNF Brain-derived neurotrophic factor
- AGEs Advanced glycation end-product
- Hypertension
- Diabetes
Advanced semantic analysis
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
Map overview Semantic statistics
Number of nodes, edges, triples, density and central hubs. Use it to gauge the size and connectivity of the map.FNDC5
Nodes37
Edges36
Triples110
Avg. degree1.95
Density0.054054
Components1
How this topic connects Entity context
Quick relationship hints grouped by predicate. Useful for spotting recurring semantic connections around the current entity.See the strongest relationship patterns around the current topic before diving into the raw triples.
FNDC5
Top relations
Bgee · 20
FNDC5 → apex of heart, cardiac muscle tissue of right atrium, cerebellar cortex, deep cerebellar nuclei, deltoid muscle, digastric muscle, extraocular muscle, gastrocnemius muscle, interventricular septum, medial vestibular nucleus, muscle of thigh, myocardium of ventricle, primary visual cortex, right hemisphere of cerebellum, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, soleus muscle, superior frontal gyrus, tibialis anterior muscle, vastus lateralis muscle
RNA expression pattern · 20
FNDC5 → apex of heart, cardiac muscle tissue of right atrium, cerebellar cortex, deep cerebellar nuclei, deltoid muscle, digastric muscle, extraocular muscle, gastrocnemius muscle, interventricular septum, medial vestibular nucleus, muscle of thigh, myocardium of ventricle, primary visual cortex, right hemisphere of cerebellum, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, soleus muscle, superior frontal gyrus, tibialis anterior muscle, vastus lateralis muscle
Gene ontology · 14
FNDC5 → biological process, endoplasmic reticulum, extracellular region, hormone activity, integral component of membrane, membrane, molecular function, peroxisomal membrane, peroxisome, plasma membrane, positive regulation of brown fat cell differentiation, regulation of signaling receptor activity, response to muscle activity, signal transduction
related to Molecular interactions · 12
FNDC5 → Additionally, BAT, BDNF, ERRα, In, Irisin, Many, PGC-1alpha, Pgc-1α, The, UCP1, WAT
related to Biosynthesis and secretion · 8
FNDC5 → After, C-terminal, FNIII, III, N-terminal, TGF, The, The FNDC5
related to history · 8
FNDC5 → Alzheimer's, III, It, Others, Separately, Shortly, The, This
related to Function · 4
FNDC5 → Due, Exercise, In, PGC-1alpha
Band · 2
FNDC5 → 1p35.1, 4|4 D2.2
Chr. · 2
FNDC5 → Chromosome 1 (human), Chromosome 4 (mouse)
End · 2
FNDC5 → 129,038,386 bp, 32,872,482 bp
Important terminology Word statistics
Frequent words and multi-word phrases across the lead, headings, infobox and body. Useful for terminology coverage.Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
Important terminology
irisin human protein expression type exercise bp gene fibronectin iii chr band study levels bdnf fat humans cells chromosome membrane
Entity relationships Subject–Predicate–Object triples
Extracted RDF-like relationships with confidence and source. The table includes structured facts and lower-confidence contextual relations.| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| FNDC5 | Aliases | FNDC5, FRCP2, irisin, Irisin, fibronectin type III domain containing 5 | 1.00 | infobox |
| FNDC5 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4LSD | 1.00 | infobox |
| FNDC5 | Band | 1p35.1 | 1.00 | infobox |
| FNDC5 | Band | 4|4 D2.2 | 1.00 | infobox |
| FNDC5 | Bgee | Skeletal muscle tissue of biceps brachii | 1.00 | infobox |
| FNDC5 | Bgee | muscle of thigh | 1.00 | infobox |
| FNDC5 | Bgee | Skeletal muscle tissue of rectus abdominis | 1.00 | infobox |
| FNDC5 | Bgee | vastus lateralis muscle | 1.00 | infobox |
| FNDC5 | Bgee | right hemisphere of cerebellum | 1.00 | infobox |
| FNDC5 | Bgee | gastrocnemius muscle | 1.00 | infobox |
| FNDC5 | Bgee | apex of heart | 1.00 | infobox |
| FNDC5 | Bgee | deltoid muscle | 1.00 | infobox |
| FNDC5 | Bgee | cardiac muscle tissue of right atrium | 1.00 | infobox |
| FNDC5 | Bgee | tibialis anterior muscle | 1.00 | infobox |
| FNDC5 | Bgee | interventricular septum | 1.00 | infobox |
| FNDC5 | Bgee | myocardium of ventricle | 1.00 | infobox |
| FNDC5 | Bgee | cerebellar cortex | 1.00 | infobox |
| FNDC5 | Bgee | soleus muscle | 1.00 | infobox |
| FNDC5 | Bgee | extraocular muscle | 1.00 | infobox |
| FNDC5 | Bgee | medial vestibular nucleus | 1.00 | infobox |
| FNDC5 | Bgee | deep cerebellar nuclei | 1.00 | infobox |
| FNDC5 | Bgee | superior frontal gyrus | 1.00 | infobox |
| FNDC5 | Bgee | digastric muscle | 1.00 | infobox |
| FNDC5 | Bgee | primary visual cortex | 1.00 | infobox |
| FNDC5 | BioGPS | n/a | 1.00 | infobox |
| FNDC5 | Chr. | Chromosome 1 (human) | 1.00 | infobox |
| FNDC5 | Chr. | Chromosome 4 (mouse) | 1.00 | infobox |
| FNDC5 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| FNDC5 | End | 32,872,482 bp | 1.00 | infobox |
| FNDC5 | End | 129,038,386 bp | 1.00 | infobox |
No triples extracted yet.
Related concept clusters Concept neighborhoods
Clusters of nearby vocabulary surrounding the topic. Scan them for adjacent concepts and language you may have missed.These clusters group vocabulary that occurs around closely connected concepts in the source material.
Connections between topic areas Semantic bridges
Bridge nodes connect otherwise separate parts of the map. Expand a row to inspect the topic groups on each side.Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.
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