Iodotyrosine deiodinase

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Iodotyrosine deiodinase topic overview

The analysis highlights Structure, Function and Clinical significance as prominent areas in the source structure around Iodotyrosine deiodinase.

Related topics: 29
Source areas: 5
Connected nodes: 34
Extracted relationships: 61
Concept neighborhoods: 15
Bridge connections: 34

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 13 topics

Structure · 7 topics

Clinical significance · 4 topics

Function · 4 topics

Mechanism · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

BRENDA: enzyme data
EC no.: 1.21.1.1
ExPASy: NiceZyme view
KEGG: enzyme entry
MetaCyc: metabolic pathway
NCBI: proteins

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure

Function

Mechanism

NADPH Nicotinamide adenine dinucleotide phosphate

Clinical significance

Hypothyroidism
Goiter Goitre
Urine
Congenital Congenital disorder

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Iodotyrosine deiodinase connects Entity context

The extracted context around Iodotyrosine deiodinase shows recurring relationship patterns in the source. For example, Iodotyrosine deiodinase → Deiodinase, Human Iodotyrosine, Iodotyrosine, Medicine, Medicine Medical Subject Headings, MeSH, Mouse Iodotyrosine, National Library, Overview, PDB, PDBe-KB, Q6PHW0, Q9DCX8, This, UniProt, United States National Library Another extracted example is Iodotyrosine deiodinase → FMN, Initially, Iodotyrosine, It, N-terminus, NADH, Substrate, The, Thus, Within. Use these groups to spot repeated connection types before inspecting the individual relationships.

Top relations

related to External links · 16

Iodotyrosine deiodinase → Deiodinase, Human Iodotyrosine, Iodotyrosine, Medicine, Medicine Medical Subject Headings, MeSH, Mouse Iodotyrosine, National Library, Overview, PDB, PDBe-KB, Q6PHW0, Q9DCX8, This, UniProt, United States National Library

related to Structure · 10

Iodotyrosine deiodinase → FMN, Initially, Iodotyrosine, It, N-terminus, NADH, Substrate, The, Thus, Within

related to Clinical significance · 9

Iodotyrosine deiodinase → Because, Furthermore, However, In, Iodide, Low, Mutations, The, To

related to Function · 7

Iodotyrosine deiodinase → However, Iodide, Iodotyrosine, The, Thus, Within, Without

related to Mechanism · 7

Iodotyrosine deiodinase → Although, Flavin, FMN, Iodotyrosine, It, NADPH-dependent, The

BRENDA · 1

Iodotyrosine deiodinase → enzyme data

EC no. · 1

Iodotyrosine deiodinase → 1.21.1.1

ExPASy · 1

Iodotyrosine deiodinase → NiceZyme view

KEGG · 1

Iodotyrosine deiodinase → enzyme entry

MetaCyc · 1

Iodotyrosine deiodinase → metabolic pathway

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

iodotyrosine deiodinase thyroid iodide enzyme hormones hormone flavin iodinated two also diiodotyrosine mono- tyrosines however known dehalogenation reductive iodothyronine catalysis

Iodotyrosine deiodinase relationships Subject–Predicate–Object triples

TTTA extracted 61 structured relationships around Iodotyrosine deiodinase. Examples in this analysis include Iodotyrosine deiodinase → BRENDA → enzyme data and Iodotyrosine deiodinase → EC no. → 1.21.1.1. The table shows each extracted connection, where it came from and its confidence.

Subject	Predicate	Object	Confidence	Src
Iodotyrosine deiodinase	BRENDA	enzyme data	1.00	infobox
Iodotyrosine deiodinase	EC no.	1.21.1.1	1.00	infobox
Iodotyrosine deiodinase	ExPASy	NiceZyme view	1.00	infobox
Iodotyrosine deiodinase	KEGG	enzyme entry	1.00	infobox
Iodotyrosine deiodinase	MetaCyc	metabolic pathway	1.00	infobox
Iodotyrosine deiodinase	NCBI	proteins	1.00	infobox
Iodotyrosine deiodinase	PDB structures	RCSB PDB PDBe PDBsum	1.00	infobox
Iodotyrosine deiodinase	PMC	articles	1.00	infobox
Iodotyrosine deiodinase	PubMed	articles	1.00	infobox
Iodotyrosine deiodinase	Rhea	reactions	1.00	infobox
Iodotyrosine deiodinase	Search	SearchPMCarticlesPubMedarticlesNCBIproteins	1.00	infobox
Iodotyrosine deiodinase	is a	membrane protein	0.90	text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Iodotyrosine deiodinase bring nearby vocabulary together. In this analysis, examples include Iodotyrosine, Iodide and Thyroid. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

Iodotyrosine deiodinase
- Iodotyrosine
- Iodide
- Thyroid
- Enzyme
- Amino
- Known
- Tyrosine
- However
- Mutations
- Diiodotyrosine
- Mono-
- Necessary
iodotyrosine deiodinase
- Iodotyrosine
- Iodide
- Thyroid
- Enzyme
- Amino
- Iodothyronine
- Known
- Tyrosine
- However
- Mutations
- Diiodotyrosine
- Mono-
deiodinase
- Iodotyrosine
- Iodide
- Thyroid
- Enzyme
- Amino
- Iodothyronine
- Known
- However
- Mutations
- Diiodotyrosine
- Mono-
- Necessary
iodide
- Thyroid
- Iodotyrosine
- Hormone
- Levels
- Tyrosine
- Hormones
- Necessary
- Selenocysteine
- Topic
- Amino
- Biosynthesis
- Catalysis
iodothyronine deiodinase
- Iodotyrosine
- Iodide
- Enzymes
- Selenocysteine
- Topic
- Uses
- Thyroid
- Active
- Catalysis
- Known
- Mammals
- Reductive
enzyme
- Substrate
- Superfamily
- Flavin
- Selenocysteine
- Topic
- Iodide
- Active
- Catalysis
- Recently
- Mutations
- Iodotyrosine
- Uses
thyroid hormone
- Biosynthesis
- Hormone
- Hormones
- Thyroid
- Tyrosines
- Iodide
- Iodinated
- Diiodotyrosine
- Mono-
- Amino
- Necessary
- Tyrosine
thyroid
- Hormone
- Hormones
- Biosynthesis
- Tyrosines
- Diiodotyrosine
- Mono-
- Necessary
- Levels
- Metabolic
- Thus
- Tyrosine
- Amino

Connections between topic areas Semantic bridges

For Iodotyrosine deiodinase, one of the stronger structural bridges in this analysis connects Iodotyrosine deiodinase with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Iodotyrosine deiodinase — Overview · splits 21 ⟂ 14

Iodotyrosine deiodinase — Structure · splits 27 ⟂ 8

Iodotyrosine deiodinase — Function · splits 30 ⟂ 5

Iodotyrosine deiodinase — Clinical significance · splits 30 ⟂ 5

Map overview Semantic statistics

Iodotyrosine deiodinase

Nodes35

Edges34

Triples61

Avg. degree1.94

Density0.057143

Components1

Source & methodology

TTTA analyzes the structure around Iodotyrosine deiodinase to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Structure, Function & Clinical significance, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Iodotyrosine deiodinase · EN edition · Analysis: TopicsToTalkAbout