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Intelectin

Intelectins are lectins (carbohydrate-binding proteins) expressed in humans and other chordates. Humans express two types of intelectins encoded by ITLN1 and ITLN2 genes respectively. Several intelectins bind microbe-specific carbohydrate residues. Therefore, intelectins have been proposed to function as immune lectins. Even though intelectins contain…

Structure, Diversity & Immune system

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Structure

C-type lectinsSelenomethionineSADHigh Five insect cellsBaculovirus
6 related topics

Diversity

Xenopus laevisLipopolysaccharide
2 related topics

Immune system

PhagocytosisRainbow trout
2 related topics

Overview

LectinsChordatesITLN1ITLN2Genes
7 related topics

Key facts & relationships

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Domains
InterPro
Entrez
398574
Organism
Xenopus laevis
Orthologs
NCBI: entry; OMA: entry
PDB
4WN0
RefSeq (mRNA)
NM_001089101.1

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Overview

Diversity

Immune system

Structure

Advanced semantic analysis

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Map overview Semantic statistics

Intelectin

Nodes22
Edges21
Triples60
Avg. degree1.91
Density0.090909
Components1

How this topic connects Entity context

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Intelectin

Top relations

related to Structure · 15
Intelectin → Although, C-type, D-glycerol, Each, GroP, High Five, However, In, Se-Met XEEL-CRD, Se-Met-labeled, Se-SAD, The, The Se-Met XEEL-CRD, XEEL, XEEL-CRD
related to Oligomeric state · 14
Intelectin → CRD, Despite, Disulfide-linked, Extensive, In, N-terminal, N-termini, SDS-PAGE, The N-terminal, Therefore, Trimeric Xenopus, X-ray, XEEL, XEEL-CRD
related to Diversity · 11
Intelectin → Human, In, Mouse, The, Two, XCGL-1, XCGL-2, Xenopus, XL35, XSL-1, XSL-2
related to Immune system · 6
Intelectin → Amphioxus, In, Increase, Mammals, Several, Tunicate
Domains · 1
Intelectin → InterPro
Entrez · 1
Intelectin → 398574
Organism · 1
Intelectin → Xenopus laevis
Orthologs · 1
Intelectin → NCBI: entry; OMA: entry
PDB · 1
Intelectin → 4WN0
RefSeq (mRNA) · 1
Intelectin → NM_001089101.1

Important terminology Word statistics

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Important terminology

intelectins hintl-1 may xeel-crd calcium site lectins immune shown ligand binding two laevis residues structural intelectin-1 also function xenopus structure

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
IntelectinDomainsInterPro1.00infobox
IntelectinEntrez3985741.00infobox
IntelectinOrganismXenopus laevis1.00infobox
IntelectinOrthologsNCBI: entry; OMA: entry1.00infobox
IntelectinPDB4WN01.00infobox
IntelectinRefSeq (mRNA)NM_001089101.11.00infobox
IntelectinRefSeq (Prot)NP_001082570.11.00infobox
IntelectinSearch forSearch forStructuresSwiss-modelDomainsInterPro1.00infobox
IntelectinStructuresSwiss-model1.00infobox
IntelectinSymbolitln11.00infobox
IntelectinUniProtQ800K01.00infobox
Intelectinis aopsonin for phagocytosis by hemocyte0.90text

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    Min side: 3
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