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Integrin alpha-1: Measurement & Overview

Integrin alpha-1 also CD49a is an integrin alpha subunit encoded in humans by the gene ITGA1. It makes up half of the α1β1 integrin duplex. Though CD49a can bind a number of ligands including collagen IV, collagen I, and others.

Language: English [EN]
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Integrin alpha-1 topic overview

The analysis highlights Measurement and Overview as prominent areas in the source structure around Integrin alpha-1.

Related topics
1
Source areas
1
Connected nodes
2
Extracted relationships
161
Concept neighborhoods
3
Bridge connections
2

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
ITGA1, CD49a, VLA1, integrin subunit alpha 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1PT6, 1QC5, 1QCY, 2L8S, 4A0Q, 2M32
Band
5q11.2 · 13 D2.2|13 64.61 cM
Bgee
Achilles tendon · gastric mucosa · right coronary artery · stromal cell of endometrium · epithelium of colon
BioGPS
n/a
Chr.
Chromosome 5 (human) · Chromosome 13 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Integrin alpha-1 connects Entity context

The extracted context around Integrin alpha-1 shows recurring relationship patterns in the source. For example, Integrin alpha-1 → acrosomal vesicle, basal part of cell, cell adhesion, cell chemotaxis, cell surface, cell-matrix adhesion, cellular extravasation, collagen binding, collagen binding involved in cell-matrix adhesion, external side of plasma membrane, extracellular exosome, extracellular matrix organization, focal adhesion, integral component of membrane, integrin alpha1-beta1 complex, integrin complex, integrin-mediated signaling pathway, membrane, membrane raft, metal ion binding Another extracted example is Integrin alpha-1 → Achilles tendon, aorta, ascending aorta, brown adipose tissue, decidua, epithelium of colon, gastric mucosa, left coronary artery, left lung lobe, popliteal artery, right coronary artery, right lung, right lung lobe, saphenous vein, sciatic nerve, stromal cell of endometrium, tibial arteries, umbilical cord, vas deferens. Use these groups to spot repeated connection types before inspecting the individual relationships.

Integrin alpha-1

Top relations

Gene ontology · 34
Integrin alpha-1 → acrosomal vesicle, basal part of cell, cell adhesion, cell chemotaxis, cell surface, cell-matrix adhesion, cellular extravasation, collagen binding, collagen binding involved in cell-matrix adhesion, external side of plasma membrane, extracellular exosome, extracellular matrix organization, focal adhesion, integral component of membrane, integrin alpha1-beta1 complex, integrin complex, integrin-mediated signaling pathway, membrane, membrane raft, metal ion binding
Bgee · 19
Integrin alpha-1 → Achilles tendon, aorta, ascending aorta, brown adipose tissue, decidua, epithelium of colon, gastric mucosa, left coronary artery, left lung lobe, popliteal artery, right coronary artery, right lung, right lung lobe, saphenous vein, sciatic nerve, stromal cell of endometrium, tibial arteries, umbilical cord, vas deferens
RNA expression pattern · 19
Integrin alpha-1 → Achilles tendon, aorta, ascending aorta, brown adipose tissue, decidua, epithelium of colon, gastric mucosa, left coronary artery, left lung lobe, popliteal artery, right coronary artery, right lung, right lung lobe, saphenous vein, sciatic nerve, stromal cell of endometrium, tibial arteries, umbilical cord, vas deferens
related to Regulation of cell adhesion, migration, and survival · 16
Integrin alpha-1 → A-Actinin, ALDH1-high, ECM, In Pancreatic Ductal Adenocarcinoma, In PDAC, Integrin, ITGA1, Kindlin, Loss, Paxillin, PDAC, Reduction, Talin, The, This, Vinculin
related to External links · 12
Integrin alpha-1 → CD49a, Cell Migration Gateway Archived, Human Integrin, Human ITGA1, ITGA1, ITGA1 Info, Medicine Medical Subject Headings, MeSH, National Library, PDB, UCSC Genome Browser, Wayback MachinePDBe-KB
related to Structure · 9
Integrin alpha-1 → Beta-1, ECM, Gene Ontology, GRCh38, Integrin, ITGA1, The, The ITGA1, Willebrand
related to Extracellular matrix adhesion and signaling · 8
Integrin alpha-1 → By, ECM, ECM-dependent, Integrin, ITGA1, ITGB1, The, These
Band · 2
Integrin alpha-1 → 13 D2.2|13 64.61 cM, 5q11.2
Chr. · 2
Integrin alpha-1 → Chromosome 13 (mouse), Chromosome 5 (human)
End · 2
Integrin alpha-1 → 115,238,500 bp, 52,959,209 bp

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

itga1 cells signaling cell expression tumor integrin adhesion migration resistance ecm progression tissue survival pdac increased pathways cd49a human immune

Integrin alpha-1 relationships Subject–Predicate–Object triples

TTTA extracted 161 structured relationships around Integrin alpha-1. Examples in this analysis include Integrin alpha-1 → Aliases → ITGA1, CD49a, VLA1, integrin subunit alpha 1 and Integrin alpha-1 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1PT6, 1QC5, 1QCY, 2L8S, 4A0Q, 2M32. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Integrin alpha-1AliasesITGA1, CD49a, VLA1, integrin subunit alpha 11.00infobox
Integrin alpha-1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1PT6, 1QC5, 1QCY, 2L8S, 4A0Q, 2M321.00infobox
Integrin alpha-1Band5q11.21.00infobox
Integrin alpha-1Band13 D2.2|13 64.61 cM1.00infobox
Integrin alpha-1BgeeAchilles tendon1.00infobox
Integrin alpha-1Bgeegastric mucosa1.00infobox
Integrin alpha-1Bgeeright coronary artery1.00infobox
Integrin alpha-1Bgeestromal cell of endometrium1.00infobox
Integrin alpha-1Bgeeepithelium of colon1.00infobox
Integrin alpha-1Bgeesaphenous vein1.00infobox
Integrin alpha-1Bgeeright lung1.00infobox
Integrin alpha-1Bgeepopliteal artery1.00infobox
Integrin alpha-1Bgeetibial arteries1.00infobox
Integrin alpha-1Bgeeleft coronary artery1.00infobox
Integrin alpha-1Bgeeright lung lobe1.00infobox
Integrin alpha-1Bgeeumbilical cord1.00infobox
Integrin alpha-1Bgeeaorta1.00infobox
Integrin alpha-1Bgeeleft lung lobe1.00infobox
Integrin alpha-1Bgeeascending aorta1.00infobox
Integrin alpha-1Bgeesciatic nerve1.00infobox
Integrin alpha-1Bgeebrown adipose tissue1.00infobox
Integrin alpha-1Bgeevas deferens1.00infobox
Integrin alpha-1Bgeedecidua1.00infobox
Integrin alpha-1BioGPSn/a1.00infobox
Integrin alpha-1Chr.Chromosome 5 (human)1.00infobox
Integrin alpha-1Chr.Chromosome 13 (mouse)1.00infobox
Integrin alpha-1DatabasesNCBI: entry; OMA: entry1.00infobox
Integrin alpha-1End52,959,209 bp1.00infobox
Integrin alpha-1End115,238,500 bp1.00infobox
Integrin alpha-1EnsemblENSG000002139491.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Integrin alpha-1 bring nearby vocabulary together. In this analysis, examples include Α1β1, Receptor and Subunit. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Integrin alpha-1
    • Α1β1
    • Receptor
    • Subunit
    • Adhesion
    • Extracellular
    • Gene
    • Signaling
    • Matrix
    • Collagen
    • Cell
    • Ecm
    • Pathways
  • integrin alpha-1
    • Α1β1
    • Receptor
    • Subunit
    • Adhesion
    • Extracellular
    • Gene
    • Signaling
    • Matrix
    • Collagen
    • Cell
    • Ecm
    • Pathways
  • integrin
    • Α1β1
    • Receptor
    • Subunit
    • Adhesion
    • Extracellular
    • Gene
    • Signaling
    • Matrix
    • Collagen
    • Cell
    • Ecm
    • Pathways

Connections between topic areas Semantic bridges

Bridges highlight paths between different parts of the Integrin alpha-1 map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Map overview Semantic statistics

Integrin alpha-1

Nodes3
Edges2
Triples161
Avg. degree1.33
Density0.666667
Components1

Source & methodology

TTTA analyzes the structure around Integrin alpha-1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Integrin alpha-1 · EN edition · Analysis: TopicsToTalkAbout

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