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Imipenem

Imipenem, sold under the brand name Primaxin among others, is a synthetic β-lactam antibiotic belonging to the carbapenems chemical class, developed by Merck scientists Burton Christensen, William Leanza, and Kenneth Wildonger in the mid-1970s. Carbapenems are highly resistant to the β-lactamase enzymes produced by many multiple drug-resistant…

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
International Drug Names
ATC code
J01DH51 (WHO)
CAS Number
64221-86-9 Y
ChEBI
CHEBI:51799 Y
ChEMBL
ChEMBL43708 Y

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Overview

Medical uses

Adverse effects

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Map overview Semantic statistics

Imipenem

Nodes30
Edges29
Triples43
Avg. degree1.93
Density0.066667
Components1

How this topic connects Entity context

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Imipenem

Top relations

related to Spectrum of bacterial susceptibility and resistance · 10
Imipenem → Acinetobacter, Actinomyces, Aeromonas, Bacteroides, Clostridium, Enterococcus, Not, Oman, Pseudomonas, Stenotrophomonas
Legal status · 4
Imipenem → AU: S4 (Prescription only), CA: ℞-only, UK: POM (Prescription only), US: ℞-only
has effect · 3
Imipenem → At, Common, People
3D model (JSmol) · 1
Imipenem → Interactive image
AHFS/Drugs.com · 1
Imipenem → International Drug Names
ATC code · 1
Imipenem → J01DH51 (WHO)
CAS Number · 1
Imipenem → 64221-86-9 Y
ChEBI · 1
Imipenem → CHEBI:51799 Y
ChEMBL · 1
Imipenem → ChEMBL43708 Y
ChemSpider · 1
Imipenem → 4445535 Y

Important terminology Word statistics

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Important terminology

developed carbapenems gram-negative bacteria thienamycin intravenous produced thus use activity medical spectrum name primaxin others key β-lactam resistant many antibiotics

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Imipenem3D model (JSmol)Interactive image1.00infobox
ImipenemAHFS/Drugs.comInternational Drug Names1.00infobox
ImipenemATC codeJ01DH51 (WHO)1.00infobox
ImipenemCAS Number64221-86-9 Y1.00infobox
ImipenemChEBICHEBI:51799 Y1.00infobox
ImipenemChEMBLChEMBL43708 Y1.00infobox
ImipenemChemSpider4445535 Y1.00infobox
ImipenemCompTox Dashboard (EPA)DTXSID20231431.00infobox
ImipenemDrugBankDB01598 Y1.00infobox
ImipenemECHA InfoCard100.058.8311.00infobox
ImipenemElimination half-life38 minutes (children), 60 minutes (adults)1.00infobox
ImipenemExcretionUrine (70%)1.00infobox
ImipenemFormulaC12H17N3O4S1.00infobox
ImipenemKEGGD04515 Y1.00infobox
ImipenemLegal statusAU: S4 (Prescription only)1.00infobox
ImipenemLegal statusCA: ℞-only1.00infobox
ImipenemLegal statusUK: POM (Prescription only)1.00infobox
ImipenemLegal statusUS: ℞-only1.00infobox
ImipenemLicense dataUS DailyMed: Imipenem1.00infobox
ImipenemMedlinePlusa6860131.00infobox
ImipenemMetabolismKidney1.00infobox
ImipenemMolar mass299.35 g·mol−11.00infobox
ImipenemPDB ligandIM2 (PDBe, RCSB PDB)1.00infobox
ImipenemPregnancy categoryAU: B31.00infobox
ImipenemProtein binding20%1.00infobox
ImipenemPubChem CID1048381.00infobox
ImipenemRoutes of administrationIntramuscular, intravenous1.00infobox
ImipenemTrade namesPrimaxin, others1.00infobox
ImipenemUNIIQ20IM7HE751.00infobox
Imipenemis atherapeutic alternative on the World Health Organization's List of Essential Medicines0.90text

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