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Ibutilide is a Class III antiarrhythmic agent that is indicated for acute cardioconversion of atrial fibrillation and atrial flutter of a recent onset to sinus rhythm. It exerts its antiarrhythmic effect by induction of slow inward sodium current, which prolongs action potential and refractory period of myocardial cells. Because of its Class III…
The analysis highlights Pharmacokinetics, Adverse effects and contraindications and Mechanism of action as prominent areas in the source structure around Ibutilide.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around Ibutilide shows recurring relationship patterns in the source. For example, Ibutilide → Class III, CYP2D6, CYP3A4, Its, P450, The, With Another extracted example is Ibutilide → After, Among, Approximately, The. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
antiarrhythmic administration class iii atrial fibrillation flutter action current heart rhythm metabolism approximately drug excreted sodium patients hours corvert excretion
TTTA extracted 44 structured relationships around Ibutilide. Examples in this analysis include Ibutilide → 3D model (JSmol) → Interactive image and Ibutilide → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Ibutilide | 3D model (JSmol) | Interactive image | 1.00 | infobox |
| Ibutilide | AHFS/Drugs.com | Monograph | 1.00 | infobox |
| Ibutilide | ATC code | C01BD05 (WHO) | 1.00 | infobox |
| Ibutilide | Bioavailability | N/A | 1.00 | infobox |
| Ibutilide | CAS Number | 122647-31-8 Y | 1.00 | infobox |
| Ibutilide | ChEMBL | ChEMBL533 Y | 1.00 | infobox |
| Ibutilide | ChemSpider | 54755 Y | 1.00 | infobox |
| Ibutilide | CompTox Dashboard (EPA) | DTXSID20861271 | 1.00 | infobox |
| Ibutilide | DrugBank | DB00308 Y | 1.00 | infobox |
| Ibutilide | Elimination half-life | 6 hours (2-12 hours) | 1.00 | infobox |
| Ibutilide | Excretion | Renal (82%), fecal | 1.00 | infobox |
| Ibutilide | Formula | C20H36N2O3S | 1.00 | infobox |
| Ibutilide | IUPHAR/BPS | 7200 | 1.00 | infobox |
| Ibutilide | KEGG | D08060 Y | 1.00 | infobox |
| Ibutilide | MedlinePlus | a601248 | 1.00 | infobox |
| Ibutilide | Metabolism | Hepatic oxidation | 1.00 | infobox |
| Ibutilide | Molar mass | 384.58 g·mol−1 | 1.00 | infobox |
| Ibutilide | Pregnancy category | C | 1.00 | infobox |
| Ibutilide | Protein binding | 40% | 1.00 | infobox |
| Ibutilide | PubChem CID | 60753 | 1.00 | infobox |
| Ibutilide | Routes of administration | Intravenous | 1.00 | infobox |
| Ibutilide | Trade names | Corvert | 1.00 | infobox |
| Ibutilide | UNII | 2436VX1U9B | 1.00 | infobox |
| Ibutilide | is a | Class III antiarrhythmic agent that is indicated for acute cardioconversion of atrial fibrillation and atrial flutter of a recent onset to sinus rhythm | 0.90 | text |
The concept neighborhoods around Ibutilide bring nearby vocabulary together. In this analysis, examples include Corvert, Distribution and Renal. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Ibutilide, one of the stronger structural bridges in this analysis connects Ibutilide with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Ibutilide to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Pharmacokinetics, Adverse effects and contraindications & Mechanism of action, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Ibutilide · EN edition · Analysis: TopicsToTalkAbout