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Hydroxyflutamide

Hydroxyflutamide (developmental code SCH-16423; also known as 2-hydroxyflutamide, HF, and OHF) is a nonsteroidal antiandrogen (NSAA) and the major active metabolite of flutamide, which is considered to be a prodrug of hydroxyflutamide as the active form. It has been reported to possess an IC50 of 700 nM for the androgen receptor (AR), which is about…

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3D model (JSmol)
Interactive image
CAS Number
52806-53-8
ChEBI
CHEBI:43064
ChEMBL
ChEMBL491
ChemSpider
82752
CompTox Dashboard (EPA)
DTXSID8033562

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Hydroxyflutamide

Nodes9
Edges8
Triples15
Avg. degree1.78
Density0.222222
Components1

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Hydroxyflutamide

Top relations

3D model (JSmol) · 1
Hydroxyflutamide → Interactive image
CAS Number · 1
Hydroxyflutamide → 52806-53-8
ChEBI · 1
Hydroxyflutamide → CHEBI:43064
ChEMBL · 1
Hydroxyflutamide → ChEMBL491
ChemSpider · 1
Hydroxyflutamide → 82752
CompTox Dashboard (EPA) · 1
Hydroxyflutamide → DTXSID8033562
Drug class · 1
Hydroxyflutamide → Nonsteroidal antiandrogen
ECHA InfoCard · 1
Hydroxyflutamide → 100.169.708
Formula · 1
Hydroxyflutamide → C11H11F3N2O4
IUPHAR/BPS · 1
Hydroxyflutamide → 2862

Important terminology Word statistics

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Important terminology

sch-16423 2-hydroxyflutamide hf ohf nonsteroidal antiandrogen flutamide prodrug ic50 bicalutamide developmental code also known nsaa major active metabolite considered form

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Hydroxyflutamide3D model (JSmol)Interactive image1.00infobox
HydroxyflutamideCAS Number52806-53-81.00infobox
HydroxyflutamideChEBICHEBI:430641.00infobox
HydroxyflutamideChEMBLChEMBL4911.00infobox
HydroxyflutamideChemSpider827521.00infobox
HydroxyflutamideCompTox Dashboard (EPA)DTXSID80335621.00infobox
HydroxyflutamideDrug classNonsteroidal antiandrogen1.00infobox
HydroxyflutamideECHA InfoCard100.169.7081.00infobox
HydroxyflutamideFormulaC11H11F3N2O41.00infobox
HydroxyflutamideIUPHAR/BPS28621.00infobox
HydroxyflutamideKEGGC142041.00infobox
HydroxyflutamideMolar mass292.214 g·mol−11.00infobox
HydroxyflutamideOther names2-Hydroxyflutamide; HF; OHF; Flutamide-hydroxide; SCH-16423; Hydroxyniphtholide; Hydroxyniftolide; α,α,α-Trifluoro-2-methyl-4'-nitro-m-lactotoluidide1.00infobox
HydroxyflutamidePubChem CID916491.00infobox
HydroxyflutamideUNII31D90UKP5Y1.00infobox

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