HUS1

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Explore the main themes, entities and connections around HUS1. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Function

Somatic cells DNA damage DNA repair Meiotic checkpoint function Meiotic recombination

9 related topics

Interactions

Interact HDAC1 PCNA RAD1 homolog RAD17

6 related topics

Overview

Protein Gene

2 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: HUS1, hHUS1 checkpoint clamp component
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3A1J, 3G65, 3GGR
Band: 7p12.3 · 11 A1|11 5.74 cM
Bgee: gonad · monocyte · sural nerve · Achilles tendon · islet of Langerhans
BioGPS: More reference expression data
Chr.: Chromosome 7 (human) · Chromosome 11 (mouse)

Topics to explore

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Overview

Function

Somatic cells Somatic cell
DNA damage DNA damage (naturally occurring)
DNA repair
Meiotic checkpoint function Meiotic recombination checkpoint
Meiotic recombination Genetic recombination
Synapsis
Homologous chromosomes Homologous chromosome
Double-strand break repair Double-strand break repair model
Cell cycle checkpoint

Interactions

Interact Protein-protein interaction
HDAC1
PCNA
RAD1 homolog
RAD17
RAD9A

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Nodes21

Edges20

Triples97

Avg. degree1.9

Density0.095238

Components1

How this topic connects Entity context

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HUS1

Top relations

Gene ontology · 27

HUS1 → cellular response to DNA damage stimulus, cellular response to ionizing radiation, checkpoint clamp complex, cytoplasm, cytosol, DNA damage checkpoint signaling, DNA repair, DNA replication, double-strand break repair via homologous recombination, embryo development, embryo development ending in birth or egg hatching, meiotic DNA integrity checkpoint signaling, mitotic cell cycle checkpoint signaling, mitotic DNA replication checkpoint signaling, mitotic intra-S DNA damage checkpoint signaling, negative regulation of DNA replication, nucleolus, nucleoplasm, nucleotide-excision repair, nucleus

Bgee · 20

HUS1 → abdominal wall, Achilles tendon, epithelium of colon, gastrocnemius muscle, genital tubercle, gonad, islet of Langerhans, monocyte, muscle of thigh, primary oocyte, primitive streak, proximal tubule, rectum, secondary oocyte, stromal cell of endometrium, substantia nigra, sural nerve, tail of embryo, ureter, zygote

RNA expression pattern · 20

related to In somatic cells · 3

HUS1 → DNA, In, RAD9-RAD1-HUS1

related to Interactions · 3

HUS1 → HDAC1, PCNA, RAD1

Band · 2

HUS1 → 11 A1|11 5.74 cM, 7p12.3

Chr. · 2

HUS1 → Chromosome 11 (mouse), Chromosome 7 (human)

End · 2

HUS1 → 47,979,615 bp, 8,961,191 bp

Aliases · 1

HUS1 → HUS1, hHUS1 checkpoint clamp component

Available structures · 1

HUS1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3A1J, 3G65, 3GGR

Important terminology Word statistics

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Important terminology

checkpoint bp gene chr human band protein complex chromosome dna damage location function component mouse cell repair cycle response 9-1-1

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
HUS1	Aliases	HUS1, hHUS1 checkpoint clamp component	1.00	infobox
HUS1	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3A1J, 3G65, 3GGR	1.00	infobox
HUS1	Band	7p12.3	1.00	infobox
HUS1	Band	11 A1\|11 5.74 cM	1.00	infobox
HUS1	Bgee	gonad	1.00	infobox
HUS1	Bgee	monocyte	1.00	infobox
HUS1	Bgee	sural nerve	1.00	infobox
HUS1	Bgee	Achilles tendon	1.00	infobox
HUS1	Bgee	islet of Langerhans	1.00	infobox
HUS1	Bgee	rectum	1.00	infobox
HUS1	Bgee	epithelium of colon	1.00	infobox
HUS1	Bgee	muscle of thigh	1.00	infobox
HUS1	Bgee	gastrocnemius muscle	1.00	infobox
HUS1	Bgee	stromal cell of endometrium	1.00	infobox
HUS1	Bgee	secondary oocyte	1.00	infobox
HUS1	Bgee	primary oocyte	1.00	infobox
HUS1	Bgee	zygote	1.00	infobox
HUS1	Bgee	tail of embryo	1.00	infobox
HUS1	Bgee	genital tubercle	1.00	infobox
HUS1	Bgee	primitive streak	1.00	infobox
HUS1	Bgee	substantia nigra	1.00	infobox
HUS1	Bgee	proximal tubule	1.00	infobox
HUS1	Bgee	ureter	1.00	infobox
HUS1	Bgee	abdominal wall	1.00	infobox
HUS1	BioGPS	More reference expression data	1.00	infobox
HUS1	Chr.	Chromosome 7 (human)	1.00	infobox
HUS1	Chr.	Chromosome 11 (mouse)	1.00	infobox
HUS1	Databases	NCBI: entry; OMA: entry	1.00	infobox
HUS1	End	47,979,615 bp	1.00	infobox
HUS1	End	8,961,191 bp	1.00	infobox

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