Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

HUS1: Function, Interactions & Overview

Checkpoint protein HUS1 is a protein that in humans is encoded by the HUS1 gene.

Language: English [EN]
Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.
100%
More settings
100% 100% 100% 100% 100%

HUS1 topic overview

The analysis highlights Function, Interactions and Overview as prominent areas in the source structure around HUS1.

Related topics
17
Source areas
3
Connected nodes
20
Extracted relationships
97
Concept neighborhoods
12
Bridge connections
20

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 9 topics
Interactions · 6 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
HUS1, hHUS1 checkpoint clamp component
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3A1J, 3G65, 3GGR
Band
7p12.3 · 11 A1|11 5.74 cM
Bgee
gonad · monocyte · sural nerve · Achilles tendon · islet of Langerhans
BioGPS
More reference expression data
Chr.
Chromosome 7 (human) · Chromosome 11 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How HUS1 connects Entity context

The extracted context around HUS1 shows recurring relationship patterns in the source. For example, HUS1 → cellular response to DNA damage stimulus, cellular response to ionizing radiation, checkpoint clamp complex, cytoplasm, cytosol, DNA damage checkpoint signaling, DNA repair, DNA replication, double-strand break repair via homologous recombination, embryo development, embryo development ending in birth or egg hatching, meiotic DNA integrity checkpoint signaling, mitotic cell cycle checkpoint signaling, mitotic DNA replication checkpoint signaling, mitotic intra-S DNA damage checkpoint signaling, negative regulation of DNA replication, nucleolus, nucleoplasm, nucleotide-excision repair, nucleus Another extracted example is HUS1 → abdominal wall, Achilles tendon, epithelium of colon, gastrocnemius muscle, genital tubercle, gonad, islet of Langerhans, monocyte, muscle of thigh, primary oocyte, primitive streak, proximal tubule, rectum, secondary oocyte, stromal cell of endometrium, substantia nigra, sural nerve, tail of embryo, ureter, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.

HUS1

Top relations

Gene ontology · 27
HUS1 → cellular response to DNA damage stimulus, cellular response to ionizing radiation, checkpoint clamp complex, cytoplasm, cytosol, DNA damage checkpoint signaling, DNA repair, DNA replication, double-strand break repair via homologous recombination, embryo development, embryo development ending in birth or egg hatching, meiotic DNA integrity checkpoint signaling, mitotic cell cycle checkpoint signaling, mitotic DNA replication checkpoint signaling, mitotic intra-S DNA damage checkpoint signaling, negative regulation of DNA replication, nucleolus, nucleoplasm, nucleotide-excision repair, nucleus
Bgee · 20
HUS1 → abdominal wall, Achilles tendon, epithelium of colon, gastrocnemius muscle, genital tubercle, gonad, islet of Langerhans, monocyte, muscle of thigh, primary oocyte, primitive streak, proximal tubule, rectum, secondary oocyte, stromal cell of endometrium, substantia nigra, sural nerve, tail of embryo, ureter, zygote
RNA expression pattern · 20
HUS1 → abdominal wall, Achilles tendon, epithelium of colon, gastrocnemius muscle, genital tubercle, gonad, islet of Langerhans, monocyte, muscle of thigh, primary oocyte, primitive streak, proximal tubule, rectum, secondary oocyte, stromal cell of endometrium, substantia nigra, sural nerve, tail of embryo, ureter, zygote
related to In somatic cells · 3
HUS1 → DNA, In, RAD9-RAD1-HUS1
related to Interactions · 3
HUS1 → HDAC1, PCNA, RAD1
Band · 2
HUS1 → 11 A1|11 5.74 cM, 7p12.3
Chr. · 2
HUS1 → Chromosome 11 (mouse), Chromosome 7 (human)
End · 2
HUS1 → 47,979,615 bp, 8,961,191 bp
Aliases · 1
HUS1 → HUS1, hHUS1 checkpoint clamp component
Available structures · 1
HUS1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3A1J, 3G65, 3GGR

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

checkpoint bp gene chr human band protein complex chromosome dna damage location function component mouse cell repair cycle response 9-1-1

HUS1 relationships Subject–Predicate–Object triples

TTTA extracted 97 structured relationships around HUS1. Examples in this analysis include HUS1 → Aliases → HUS1, hHUS1 checkpoint clamp component and HUS1 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3A1J, 3G65, 3GGR. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
HUS1AliasesHUS1, hHUS1 checkpoint clamp component1.00infobox
HUS1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3A1J, 3G65, 3GGR1.00infobox
HUS1Band7p12.31.00infobox
HUS1Band11 A1|11 5.74 cM1.00infobox
HUS1Bgeegonad1.00infobox
HUS1Bgeemonocyte1.00infobox
HUS1Bgeesural nerve1.00infobox
HUS1BgeeAchilles tendon1.00infobox
HUS1Bgeeislet of Langerhans1.00infobox
HUS1Bgeerectum1.00infobox
HUS1Bgeeepithelium of colon1.00infobox
HUS1Bgeemuscle of thigh1.00infobox
HUS1Bgeegastrocnemius muscle1.00infobox
HUS1Bgeestromal cell of endometrium1.00infobox
HUS1Bgeesecondary oocyte1.00infobox
HUS1Bgeeprimary oocyte1.00infobox
HUS1Bgeezygote1.00infobox
HUS1Bgeetail of embryo1.00infobox
HUS1Bgeegenital tubercle1.00infobox
HUS1Bgeeprimitive streak1.00infobox
HUS1Bgeesubstantia nigra1.00infobox
HUS1Bgeeproximal tubule1.00infobox
HUS1Bgeeureter1.00infobox
HUS1Bgeeabdominal wall1.00infobox
HUS1BioGPSMore reference expression data1.00infobox
HUS1Chr.Chromosome 7 (human)1.00infobox
HUS1Chr.Chromosome 11 (mouse)1.00infobox
HUS1DatabasesNCBI: entry; OMA: entry1.00infobox
HUS1End47,979,615 bp1.00infobox
HUS1End8,961,191 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around HUS1 bring nearby vocabulary together. In this analysis, examples include Gene, Clamp and Component. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • HUS1
    • Gene
    • Clamp
    • Component
    • Encoded
    • Search
    • Function
    • Location
    • Chromosome
    • Human
    • Protein
    • Bp
    • Chr
  • hus1
    • Gene
    • Clamp
    • Component
    • Encoded
    • Search
    • Function
    • Location
    • Chromosome
    • Human
    • Protein
    • Bp
    • Chr
  • gene
    • Location
    • Chromosome
    • Human
    • Hus1
    • A1
    • Bp
    • Chr
    • Clamp
    • Component
    • End
    • Mouse
    • Search
  • meiotic checkpoint function
    • Clamp
    • Component
    • Search
    • Location
    • Protein
    • Complex
    • Chromosome
    • Gene
    • Human
    • Hus1
    • Function
    • Bp
  • double-strand break repair
    • Cell
    • Cycle
    • Double-strand
    • Repair
    • 9-1-1
    • Clamp
    • Component
    • Encoded
    • End
    • Meiosis
    • Mouse
    • Response
  • cell cycle checkpoint
    • Break
    • Cycle
    • Double-strand
    • Repair
    • Protein
    • Complex
    • Function
    • Binding
    • Clamp
    • Component
    • Damage
    • Dna
  • function
    • Clamp
    • Component
    • Search
    • Location
    • Chromosome
    • Gene
    • Human
    • Hus1
    • Bp
    • Chr
    • Complex
    • A1
  • somatic cells
    • Cells
    • Somatic
    • Clamp
    • Component
    • Meiosis
    • Search
    • 9-1-1
    • Function
    • Location
    • Repair
    • Chromosome
    • Damage

Connections between topic areas Semantic bridges

For HUS1, one of the stronger structural bridges in this analysis connects HUS1 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
HUS1Function · splits 11 ⟂ 10
HUS1Interactions · splits 14 ⟂ 7
HUS1Overview · splits 18 ⟂ 3

Map overview Semantic statistics

HUS1

Nodes21
Edges20
Triples97
Avg. degree1.9
Density0.095238
Components1

Source & methodology

TTTA analyzes the structure around HUS1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — HUS1 · EN edition · Analysis: TopicsToTalkAbout

For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.