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HSD17B2

17β-Hydroxysteroid dehydrogenase 2 (17β-HSD2) is an enzyme of the 17β-hydroxysteroid dehydrogenase (17β-HSD) family that in humans is encoded by the HSD17B2 gene.

Function, Expression & Clinical significance

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1.1.1.239
1.1.1.62
Aliases
HSD17B2, EDH17B2, HSD17, SDR9C2, hydroxysteroid (17-beta) dehydrogenase 2, hydroxysteroid 17-beta dehydrogenase 2
Band
16q23.3 · 8|8 E1
Bgee
jejunal mucosa · duodenum · mucosa of transverse colon · mucosa of ileum · right lobe of liver
BioGPS
More reference expression data

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Overview

Function

Expression

Clinical significance

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Map overview Semantic statistics

HSD17B2

Nodes41
Edges40
Triples79
Avg. degree1.95
Density0.04878
Components1

How this topic connects Entity context

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HSD17B2

Top relations

Bgee · 20
HSD17B2 → corneal stroma, duodenum, epithelium of stomach, esophagus, ileum, jejunal mucosa, jejunum, left colon, left lobe of liver, mucosa of ileum, mucosa of sigmoid colon, mucosa of transverse colon, mucosa of urinary bladder, olfactory zone of nasal mucosa, placenta, pyloric antrum, rectum, right lobe of liver, transitional epithelium of urinary bladder, yolk sac
RNA expression pattern · 20
HSD17B2 → corneal stroma, duodenum, epithelium of stomach, esophagus, ileum, jejunal mucosa, jejunum, left colon, left lobe of liver, mucosa of ileum, mucosa of sigmoid colon, mucosa of transverse colon, mucosa of urinary bladder, olfactory zone of nasal mucosa, placenta, pyloric antrum, rectum, right lobe of liver, transitional epithelium of urinary bladder, yolk sac
Gene ontology · 13
HSD17B2 → 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity, endoplasmic reticulum membrane, estradiol 17-beta-dehydrogenase activity, estrogen biosynthetic process, in utero embryonic development, integral component of membrane, lipid metabolism, membrane, oxidoreductase activity, placenta development, response to retinoic acid, steroid biosynthetic process, testosterone dehydrogenase (NAD+) activity
related to Clinical significance · 3
HSD17B2 → HSD2, Inactivating, Polymorphisms
Band · 2
HSD17B2 → 16q23.3, 8|8 E1
Chr. · 2
HSD17B2 → Chromosome 16 (human), Chromosome 8 (mouse)
End · 2
HSD17B2 → 118,485,766 bp, 82,098,534 bp
1.1.1.239 · 1
HSD17B2 → ↗
1.1.1.62 · 1
HSD17B2 → ↗
Aliases · 1
HSD17B2 → HSD17B2, EDH17B2, HSD17, SDR9C2, hydroxysteroid (17-beta) dehydrogenase 2, hydroxysteroid 17-beta dehydrogenase 2

Important terminology Word statistics

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Important terminology

bp chr human band gene 17β-hsd2 dehydrogenase chromosome 16 enzyme activity location 17β-hsd mouse function expression 098 534 end 82

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
HSD17B21.1.1.2391.00infobox
HSD17B21.1.1.621.00infobox
HSD17B2AliasesHSD17B2, EDH17B2, HSD17, SDR9C2, hydroxysteroid (17-beta) dehydrogenase 2, hydroxysteroid 17-beta dehydrogenase 21.00infobox
HSD17B2Band16q23.31.00infobox
HSD17B2Band8|8 E11.00infobox
HSD17B2Bgeejejunal mucosa1.00infobox
HSD17B2Bgeeduodenum1.00infobox
HSD17B2Bgeemucosa of transverse colon1.00infobox
HSD17B2Bgeemucosa of ileum1.00infobox
HSD17B2Bgeeright lobe of liver1.00infobox
HSD17B2Bgeerectum1.00infobox
HSD17B2Bgeeplacenta1.00infobox
HSD17B2Bgeemucosa of urinary bladder1.00infobox
HSD17B2Bgeemucosa of sigmoid colon1.00infobox
HSD17B2Bgeeolfactory zone of nasal mucosa1.00infobox
HSD17B2Bgeeleft lobe of liver1.00infobox
HSD17B2Bgeetransitional epithelium of urinary bladder1.00infobox
HSD17B2Bgeeleft colon1.00infobox
HSD17B2Bgeeesophagus1.00infobox
HSD17B2Bgeepyloric antrum1.00infobox
HSD17B2Bgeeyolk sac1.00infobox
HSD17B2Bgeeileum1.00infobox
HSD17B2Bgeeepithelium of stomach1.00infobox
HSD17B2Bgeejejunum1.00infobox
HSD17B2Bgeecorneal stroma1.00infobox
HSD17B2BioGPSMore reference expression data1.00infobox
HSD17B2Chr.Chromosome 16 (human)1.00infobox
HSD17B2Chr.Chromosome 8 (mouse)1.00infobox
HSD17B2DatabasesNCBI: entry; OMA: entry1.00infobox
HSD17B2End82,098,534 bp1.00infobox

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