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Hypoxanthine-guanine phosphoribosyltransferase

Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) is an enzyme encoded in humans by the HPRT1 gene.

Role in disease, Creation of hybridomas & Substrates and inhibitors

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Explore the main themes, entities and connections around Hypoxanthine-guanine phosphoribosyltransferase. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Aliases
HPRTinosinic pyrophosphorylaseinosinate pyrophosphorylaseinosinic acid pyrophosphorylaseinosine 5'-phosphate pyrophosphorylaseIMP:diphosphate phospho-D-ribosyltransferaseHGPRTas…
Databases
n/a
Ensembl
n/a
Entrez
n/a
External IDs
GeneCards:
Location (UCSC)
n/a

Topics to explore

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Overview

Function

Substrates and inhibitors

Role in disease

Creation of hybridomas

Advanced semantic analysis

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Map overview Semantic statistics

Hypoxanthine-guanine phosphoribosyltransferase

Nodes44
Edges43
Triples26
Avg. degree1.95
Density0.045455
Components1

How this topic connects Entity context

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Hypoxanthine-guanine phosphoribosyltransferase

Top relations

related to Role in disease · 13
Hypoxanthine-guanine phosphoribosyltransferase → At, HGPRT, HIF-1, HIF1A, HPRT, HPRT1, Kelley, Lesch, Mutations, Nyhan, Seegmiller, Some, This
Aliases · 1
Hypoxanthine-guanine phosphoribosyltransferase → HPRTinosinic pyrophosphorylaseinosinate pyrophosphorylaseinosinic acid pyrophosphorylaseinosine 5'-phosphate pyrophosphorylaseIMP:diphosphate phospho-D-ribosyltransferaseHGPRTas…
Databases · 1
Hypoxanthine-guanine phosphoribosyltransferase → n/a
Ensembl · 1
Hypoxanthine-guanine phosphoribosyltransferase → n/a
Entrez · 1
Hypoxanthine-guanine phosphoribosyltransferase → n/a
External IDs · 1
Hypoxanthine-guanine phosphoribosyltransferase → GeneCards:
Location (UCSC) · 1
Hypoxanthine-guanine phosphoribosyltransferase → n/a
Orthologs · 1
Hypoxanthine-guanine phosphoribosyltransferase → OrthologsDatabasesn/aSpeciesHumanMouseEntrezn/an/aEnsembln/an/aUniProtn an/aRefSeq (mRNA)n/an/aRefSeq (protein)n/an/aLocation (UCSC)n/an/aPubMed searchn/an/a
PubMed search · 1
Hypoxanthine-guanine phosphoribosyltransferase → n/a
RefSeq (mRNA) · 1
Hypoxanthine-guanine phosphoribosyltransferase → n/a

Important terminology Word statistics

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Important terminology

hgprt purine hypoxanthine role enzyme gene phosphoribosyltransferase hprt1 catalyzes monophosphate guanosine salvage pathway guanine acid external mutations deficiency syndrome cells

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Hypoxanthine-guanine phosphoribosyltransferaseAliasesHPRTinosinic pyrophosphorylaseinosinate pyrophosphorylaseinosinic acid pyrophosphorylaseinosine 5'-phosphate pyrophosphorylaseIMP:diphosphate phospho-D-ribosyltransferaseHGPRTas…1.00infobox
Hypoxanthine-guanine phosphoribosyltransferaseDatabasesn/a1.00infobox
Hypoxanthine-guanine phosphoribosyltransferaseEnsembln/a1.00infobox
Hypoxanthine-guanine phosphoribosyltransferaseEntrezn/a1.00infobox
Hypoxanthine-guanine phosphoribosyltransferaseExternal IDsGeneCards:1.00infobox
Hypoxanthine-guanine phosphoribosyltransferaseLocation (UCSC)n/a1.00infobox
Hypoxanthine-guanine phosphoribosyltransferaseOrthologsOrthologsDatabasesn/aSpeciesHumanMouseEntrezn/an/aEnsembln/an/aUniProtn an/aRefSeq (mRNA)n/an/aRefSeq (protein)n/an/aLocation (UCSC)n/an/aPubMed searchn/an/a1.00infobox
Hypoxanthine-guanine phosphoribosyltransferasePubMed searchn/a1.00infobox
Hypoxanthine-guanine phosphoribosyltransferaseRefSeq (mRNA)n/a1.00infobox
Hypoxanthine-guanine phosphoribosyltransferaseRefSeq (protein)n/a1.00infobox
Hypoxanthine-guanine phosphoribosyltransferaseSpeciesHuman1.00infobox
Hypoxanthine-guanine phosphoribosyltransferaseUniProtn a1.00infobox

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