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Glutarimide

Glutarimide, also known as piperidine-2,6-dione, is an organic compound with the chemical formula C5H7NO2. It is a white crystalline powder formed by the dehydration of the amide of glutaric acid. Glutarimide serves as a core structural component in several pharmacologically active compounds, including thalidomide, lenalidomide, cycloheximide, and…

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Pharmacology

Cereblon
1 related topics

Overview

ThalidomideLenalidomideCycloheximideGlutethimide
4 related topics

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Overview

Pharmacology

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Glutarimide

Nodes8
Edges7
Triples14
Avg. degree1.75
Density0.25
Components1

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Glutarimide

Top relations

related to history · 5
Glutarimide → CRBN-targeted, ENL, IMiDs, Its, Thalidomide’s
related to Pharmacology · 5
Glutarimide → CRBN, Cycloheximide, Derivatives, E3, The
related to Chemical properties · 4
Glutarimide → C5H7NO2, It, Its, N-Acyl-glutarimides

Important terminology Word statistics

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Important terminology

chemical formula synthesis compound c5h7no2 thalidomide lenalidomide protein glutaric acid also properties cycloheximide glutethimide key piperidine-2 6-dione references pharmacological organic

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Glutarimiderelated to Chemical propertiesIts0.60section
Glutarimiderelated to Chemical propertiesC5H7NO20.60section
Glutarimiderelated to Chemical propertiesIt0.60section
Glutarimiderelated to Chemical propertiesN-Acyl-glutarimides0.60section
Glutarimiderelated to historyIts0.60section
Glutarimiderelated to historyThalidomide’s0.60section
Glutarimiderelated to historyENL0.60section
Glutarimiderelated to historyIMiDs0.60section
Glutarimiderelated to historyCRBN-targeted0.60section
Glutarimiderelated to PharmacologyDerivatives0.60section
Glutarimiderelated to PharmacologyCRBN0.60section
Glutarimiderelated to PharmacologyE30.60section

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