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Gap junction alpha-8 protein is a protein that in humans is encoded by the GJA8 gene. It is also known as connexin 50.
The analysis highlights Related gene problems, Interactions and Overview as prominent areas in the source structure around GJA8.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
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The extracted context around GJA8 shows recurring relationship patterns in the source. For example, GJA8 → camera-type eye development, cell communication, cell junction, cell-cell signaling, channel activity, connexin complex, gap junction, gap junction channel activity, gap junction-mediated intercellular transport, integral component of membrane, integral component of plasma membrane, lens development in camera-type eye, membrane, plasma membrane, protein homooligomerization, transmembrane transport, visual perception Another extracted example is GJA8 → adipose tissue, connective tissue, epithelium of lens, human kidney, kidney, left testis, lens, muscle tissue, neural layer of retina, right lobe of liver, right testis, smooth muscle tissue, sternocleidomastoid muscle, tail of embryo, viscus. Use these groups to spot repeated connection types before inspecting the individual relationships.
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bp gene chr human band protein junction chromosome gap location mouse connexin 909 269 end 147 f2 833 336 1q21
TTTA extracted 68 structured relationships around GJA8. Examples in this analysis include GJA8 → Aliases → GJA8, CAE, CAE1, CTRCT1, CX50, CZP1, MP70, gap junction protein alpha 8 and GJA8 → Band → 1q21.2. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| GJA8 | Aliases | GJA8, CAE, CAE1, CTRCT1, CX50, CZP1, MP70, gap junction protein alpha 8 | 1.00 | infobox |
| GJA8 | Band | 1q21.2 | 1.00 | infobox |
| GJA8 | Band | 3 F2.1|3 | 1.00 | infobox |
| GJA8 | Bgee | left testis | 1.00 | infobox |
| GJA8 | Bgee | right testis | 1.00 | infobox |
| GJA8 | Bgee | muscle tissue | 1.00 | infobox |
| GJA8 | Bgee | kidney | 1.00 | infobox |
| GJA8 | Bgee | human kidney | 1.00 | infobox |
| GJA8 | Bgee | connective tissue | 1.00 | infobox |
| GJA8 | Bgee | smooth muscle tissue | 1.00 | infobox |
| GJA8 | Bgee | adipose tissue | 1.00 | infobox |
| GJA8 | Bgee | right lobe of liver | 1.00 | infobox |
| GJA8 | Bgee | viscus | 1.00 | infobox |
| GJA8 | Bgee | lens | 1.00 | infobox |
| GJA8 | Bgee | epithelium of lens | 1.00 | infobox |
| GJA8 | Bgee | neural layer of retina | 1.00 | infobox |
| GJA8 | Bgee | tail of embryo | 1.00 | infobox |
| GJA8 | Bgee | sternocleidomastoid muscle | 1.00 | infobox |
| GJA8 | BioGPS | More reference expression data | 1.00 | infobox |
| GJA8 | Chr. | Chromosome 1 (human) | 1.00 | infobox |
| GJA8 | Chr. | Chromosome 3 (mouse) | 1.00 | infobox |
| GJA8 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| GJA8 | End | 147,909,269 bp | 1.00 | infobox |
| GJA8 | End | 96,833,336 bp | 1.00 | infobox |
| GJA8 | Ensembl | ENSG00000121634 | 1.00 | infobox |
| GJA8 | Entrez | 2703 | 1.00 | infobox |
| GJA8 | External IDs | OMIM: 600897; MGI: 99953; GeneCards: GJA8 | 1.00 | infobox |
| GJA8 | Gene location (Human) | Gene location (Human)Chr.Chromosome 1 (human)Band1q21.2Start147,902,795 bpEnd147,909,269 bp | 1.00 | infobox |
| GJA8 | Gene location (Mouse) | Gene location (Mouse)Chr.Chromosome 3 (mouse)Band3 F2.1|3Start96,820,882 bpEnd96,833,336 bp | 1.00 | infobox |
| GJA8 | Gene ontology | channel activity | 1.00 | infobox |
The concept neighborhoods around GJA8 bring nearby vocabulary together. In this analysis, examples include Junction, Protein and Gene. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For GJA8, one of the stronger structural bridges in this analysis connects GJA8 with Related gene problems. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around GJA8 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Related gene problems, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — GJA8 · EN edition · Analysis: TopicsToTalkAbout
