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TNFRSF18

Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), also known as glucocorticoid-induced TNFR-related protein (GITR) or CD357. GITR is encoded and tnfrsf18 gene at chromosome 4 in mice. GITR is type I transmembrane protein and is described in 4 different isoforms. GITR human orthologue, also called activation-inducible TNFR family receptor…

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Aliases
TNFRSF18, AITR, CD357, GITR, GITR-D, tumor necrosis factor receptor superfamily member 18, TNF receptor superfamily member 18, ENERGEN
Band
1p36.33 · 4|4 E2
Bgee
skin of abdomen · granulocyte · skin of leg · cartilage tissue · nasal epithelium
BioGPS
n/a
Chr.
Chromosome 1 (human) · Chromosome 4 (mouse)
Databases
NCBI: entry; OMA: entry

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Tissue distribution

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TNFRSF18

Nodes5
Edges4
Triples80
Avg. degree1.6
Density0.4
Components1

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TNFRSF18

Top relations

Gene ontology · 22
TNFRSF18 → apoptotic process, apoptotic signaling pathway, extracellular region, immune response, inflammatory response, integral component of membrane, integral component of plasma membrane, membrane, multicellular organism development, negative regulation of apoptotic process, plasma membrane, positive regulation of cell adhesion, positive regulation of leukocyte migration, positive regulation of tyrosine phosphorylation of STAT protein, protein binding, regulation of apoptotic process, regulation of cell population proliferation, regulation of regulatory T cell differentiation, response to lipopolysaccharide, signal transduction
Bgee · 19
TNFRSF18 → blood, cartilage tissue, genital tubercle, granulocyte, lip, mesenteric lymph nodes, mucosa of transverse colon, nasal epithelium, neural layer of retina, olfactory zone of nasal mucosa, skin of abdomen, skin of arm, skin of leg, spleen, tail of embryo, testicle, thymus, tibialis anterior muscle, zone of skin
RNA expression pattern · 19
TNFRSF18 → blood, cartilage tissue, genital tubercle, granulocyte, lip, mesenteric lymph nodes, mucosa of transverse colon, nasal epithelium, neural layer of retina, olfactory zone of nasal mucosa, skin of abdomen, skin of arm, skin of leg, spleen, tail of embryo, testicle, thymus, tibialis anterior muscle, zone of skin
Band · 2
TNFRSF18 → 1p36.33, 4|4 E2
Chr. · 2
TNFRSF18 → Chromosome 1 (human), Chromosome 4 (mouse)
End · 2
TNFRSF18 → 1,206,592 bp, 156,113,352 bp
Aliases · 1
TNFRSF18 → TNFRSF18, AITR, CD357, GITR, GITR-D, tumor necrosis factor receptor superfamily member 18, TNF receptor superfamily member 18, ENERGEN
BioGPS · 1
TNFRSF18 → n/a
Databases · 1
TNFRSF18 → NCBI: entry; OMA: entry
Ensembl · 1
TNFRSF18 → ENSG00000186891

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Important terminology

gitr cells signaling human receptor chromosome gene bp expression also regulatory chr band protein aitr activation tumor necrosis expressed cell

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
TNFRSF18AliasesTNFRSF18, AITR, CD357, GITR, GITR-D, tumor necrosis factor receptor superfamily member 18, TNF receptor superfamily member 18, ENERGEN1.00infobox
TNFRSF18Band1p36.331.00infobox
TNFRSF18Band4|4 E21.00infobox
TNFRSF18Bgeeskin of abdomen1.00infobox
TNFRSF18Bgeegranulocyte1.00infobox
TNFRSF18Bgeeskin of leg1.00infobox
TNFRSF18Bgeecartilage tissue1.00infobox
TNFRSF18Bgeenasal epithelium1.00infobox
TNFRSF18Bgeetesticle1.00infobox
TNFRSF18Bgeeskin of arm1.00infobox
TNFRSF18Bgeeolfactory zone of nasal mucosa1.00infobox
TNFRSF18Bgeetibialis anterior muscle1.00infobox
TNFRSF18Bgeemucosa of transverse colon1.00infobox
TNFRSF18Bgeeneural layer of retina1.00infobox
TNFRSF18Bgeethymus1.00infobox
TNFRSF18Bgeeblood1.00infobox
TNFRSF18Bgeelip1.00infobox
TNFRSF18Bgeegenital tubercle1.00infobox
TNFRSF18Bgeespleen1.00infobox
TNFRSF18Bgeetail of embryo1.00infobox
TNFRSF18Bgeemesenteric lymph nodes1.00infobox
TNFRSF18Bgeezone of skin1.00infobox
TNFRSF18BioGPSn/a1.00infobox
TNFRSF18Chr.Chromosome 1 (human)1.00infobox
TNFRSF18Chr.Chromosome 4 (mouse)1.00infobox
TNFRSF18DatabasesNCBI: entry; OMA: entry1.00infobox
TNFRSF18End1,206,592 bp1.00infobox
TNFRSF18End156,113,352 bp1.00infobox
TNFRSF18EnsemblENSG000001868911.00infobox
TNFRSF18Entrez87841.00infobox

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