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GFER

Growth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae), also known as GFER, or Hepatopoietin is a protein which in humans is encoded by the GFER gene. This gene is also known as essential for respiration and vegatative growth, augmenter of liver regeneration, and growth factor of Erv1-like/Hepatic regenerative stimulation substance.

[EN, English, English]

Structure, Clinical significance & Interactions

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Key facts & relationships

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1.8.3.2
Aliases
GFER, ALR, ERV1, HERV1, HPO, HPO1, HPO2, HSS, growth factor, augmenter of liver regeneration, MMCHD, MPMCD
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3MBG, 3O55, 3TK0, 3U2L, 3U2M, 3U5S, 4LDK
Band
16p13.3 · 17 A3.3|17 12.48 cM
Bgee
vena cava · mucosa of transverse colon · body of pancreas · muscle of thigh · olfactory zone of nasal mucosa
BioGPS
More reference expression data

Topics to explore

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Overview

Structure

Genomics

Function

Clinical significance

Interactions

Advanced semantic analysis

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Map overview Semantic statistics

Number of nodes, edges, triples, density and central hubs. Use it to gauge the size and connectivity of the map.

GFER

Nodes24
Edges23
Triples87
Avg. degree1.92
Density0.083333
Components1

How this topic connects Entity context

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GFER

Top relations

Bgee · 20
GFER → body of pancreas, body of tongue, embryo, epiblast, gastrocnemius muscle, granulocyte, Ileal epithelium, left lobe of liver, mucosa of transverse colon, muscle of thigh, olfactory zone of nasal mucosa, Paneth cell, primary oocyte, proximal tubule, right kidney, right lobe of liver, right testis, seminiferous tubule, triceps brachii muscle, vena cava
RNA expression pattern · 20
GFER → body of pancreas, body of tongue, embryo, epiblast, gastrocnemius muscle, granulocyte, Ileal epithelium, left lobe of liver, mucosa of transverse colon, muscle of thigh, olfactory zone of nasal mucosa, Paneth cell, primary oocyte, proximal tubule, right kidney, right lobe of liver, right testis, seminiferous tubule, triceps brachii muscle, vena cava
Gene ontology · 15
GFER → cytoplasm, cytosol, extracellular region, flavin adenine dinucleotide binding, flavin-linked sulfhydryl oxidase activity, growth factor activity, liver development, mitochondrial intermembrane space, mitochondrion, oxidoreductase activity, protein binding, protein-disulfide reductase activity, regulation of signaling receptor activity, signal transduction, thiol oxidase activity
related to Clinical significance · 3
GFER → MPMCHD, Mutations, Myopathy
Band · 2
GFER → 16p13.3, 17 A3.3|17 12.48 cM
Chr. · 2
GFER → Chromosome 16 (human), Chromosome 17 (mouse)
End · 2
GFER → 1,987,749 bp, 24,915,130 bp
related to Interactions · 2
GFER → BNIPL, COP9
related to Structure · 2
GFER → The, The GFER
1.8.3.2 · 1
GFER → ↗

Important terminology Word statistics

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Important terminology

gene bp human chromosome 16 factor liver chr band growth protein augmenter regeneration scerv1 also location yeast homolog regenerative 130

Entity relationships Subject–Predicate–Object triples

Extracted RDF-like relationships with confidence and source. The table includes structured facts and lower-confidence contextual relations.
SubjectPredicateObjectConfidenceSrc
GFER1.8.3.21.00infobox
GFERAliasesGFER, ALR, ERV1, HERV1, HPO, HPO1, HPO2, HSS, growth factor, augmenter of liver regeneration, MMCHD, MPMCD1.00infobox
GFERAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3MBG, 3O55, 3TK0, 3U2L, 3U2M, 3U5S, 4LDK1.00infobox
GFERBand16p13.31.00infobox
GFERBand17 A3.3|17 12.48 cM1.00infobox
GFERBgeevena cava1.00infobox
GFERBgeemucosa of transverse colon1.00infobox
GFERBgeebody of pancreas1.00infobox
GFERBgeemuscle of thigh1.00infobox
GFERBgeeolfactory zone of nasal mucosa1.00infobox
GFERBgeegranulocyte1.00infobox
GFERBgeebody of tongue1.00infobox
GFERBgeeright lobe of liver1.00infobox
GFERBgeeright testis1.00infobox
GFERBgeegastrocnemius muscle1.00infobox
GFERBgeeseminiferous tubule1.00infobox
GFERBgeeprimary oocyte1.00infobox
GFERBgeeIleal epithelium1.00infobox
GFERBgeeleft lobe of liver1.00infobox
GFERBgeePaneth cell1.00infobox
GFERBgeetriceps brachii muscle1.00infobox
GFERBgeeembryo1.00infobox
GFERBgeeproximal tubule1.00infobox
GFERBgeeepiblast1.00infobox
GFERBgeeright kidney1.00infobox
GFERBioGPSMore reference expression data1.00infobox
GFERChr.Chromosome 16 (human)1.00infobox
GFERChr.Chromosome 17 (mouse)1.00infobox
GFERDatabasesNCBI: entry; OMA: entry1.00infobox
GFEREnd1,987,749 bp1.00infobox

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