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FtsK

FtsK is a protein involved in bacterial cell division and chromosome segregation. In E. coli, is one of the largest proteins, consisting of 1329 amino acids. FtsK stands for "Filament temperature sensitive mutant K" because cells expressing a mutant ftsK allele called ftsK44, which encodes an FtsK variant containing an G80A residue change in the second…

Regions, Phylogeny & Mechanism of action

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Phylogeny

SsDNAE. coliStaphyloccusStreptomycetesArchaea
7 related topics

Mechanism of action

RecombinaseDNA translocationConformational changeDivisome
4 related topics

Structure

Transmembrane proteinATP hydrolysisTranslocase
3 related topics

Role in cell division

SeptumSuppressor mutationPeriplasm
3 related topics

Key facts & relationships

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AlphaFold
IPR041027 · PF17854
Available protein structures:
IPR041027 · PF17854
CATH
2j5o
CDD
407717
InterPro
IPR041027
PDB
IPR041027 PF17854 (ECOD; PDBsum)

Topics to explore

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Overview

Structure

Mechanism of action

Role in cell division

Phylogeny

Advanced semantic analysis

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Map overview Semantic statistics

FtsK

Nodes26
Edges25
Triples86
Avg. degree1.92
Density0.076923
Components1

How this topic connects Entity context

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FtsK

Top relations

related to Phylogeny · 17
FtsK → AAA, Actinomycetota, Although FtsK, Archaea, ATPases, Bacillota, Each, Gram, SpoIIIE, Staphyloccus, Streptomycetes, T4CPs, TcpA, The, TraB, VirB4/VirD4, VirB4s
related to Structure · 16
FtsK → Additionally, ATP, C-terminal, DNA, Found, FtsKC, FtsKL, FtsKN, It, N-terminal, The, The ATP, The FtsKL, The FtsKN, This, Xer
related to Recombinase (Xer D) activation · 10
FtsK → ATP, Contact, DNA, During, FtsKc, Specifically, The, The Xer, Xer, XerCD
related to Translocation · 10
FtsK → Additionally, Conformational, Conversely, DNA, FtsKC, In, The, There, These, This
related to Role in cell division · 9
FtsK → Dubarry, Escherichia, FtsKN, FtsW, However, In, Other, The N-terminal, When
related to Binding site · 6
FtsK → DNA, Guanosine, KOPS, Movement, These, Upon
related to The dif site · 5
FtsK → FtsKC, It, The, Translocation, Xer
AlphaFold · 2
FtsK → IPR041027, PF17854
Available protein structures: · 2
FtsK → IPR041027, PF17854
is a · 2
FtsK → fastest DNA translocation pump, protein involved in bacterial cell division and chromosome segregation

Important terminology Word statistics

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Important terminology

dna cell domain division translocation chromosome xer protein ftskc hexamer mechanism dif site bacteria proteins dimer segregation recombination ftskn found

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
FtsKAlphaFoldIPR0410271.00infobox
FtsKAlphaFoldPF178541.00infobox
FtsKAvailable protein structures:IPR0410271.00infobox
FtsKAvailable protein structures:PF178541.00infobox
FtsKCATH2j5o1.00infobox
FtsKCDD4077171.00infobox
FtsKInterProIPR0410271.00infobox
FtsKPDBIPR041027 PF17854 (ECOD; PDBsum)1.00infobox
FtsKPfamPF178541.00infobox
FtsKSCOP22j5o / SCOPe / SUPFAM1.00infobox
FtsKSymbolFtsK_alpha1.00infobox
FtsKis aprotein involved in bacterial cell division and chromosome segregation0.90text
FtsKis afastest DNA translocation pump0.90text

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