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Flavin-containing monooxygenase 3: Overview & Cancer

Flavin-containing monooxygenase 3 (FMO3), also known as dimethylaniline monooxygenase [N-oxide-forming] 3 and trimethylamine monooxygenase, is a flavoprotein enzyme (EC 1.14.13.148) that in humans is encoded by the FMO3 gene. This enzyme catalyzes the following chemical reaction, among others:

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Flavin-containing monooxygenase 3 topic overview

The analysis highlights Overview and Cancer as prominent areas in the source structure around Flavin-containing monooxygenase 3.

Related topics
27
Source areas
2
Connected nodes
29
Extracted relationships
78
Related term clusters
12
Bridge connections
29

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 24 topics
Cancer · 3 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

1.14.13.148
↗
1.14.13.32
↗
1.14.13.8
↗
Aliases
FMO3, trimethylamine monooxygenase, flavin-containing monooxygenase 3, Dimethylaniline monooxygenase [N-oxide-forming] 3, FMOII, TMAU, dJ127D3.1, flavin containing monooxygenase…
Band
1q24.3 · 1 H2.1|1 70.34 cM
Bgee
right lobe of liver · olfactory zone of nasal mucosa · nasal epithelium · right lung · mucosa of paranasal sinus

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Flavin-containing monooxygenase 3

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Cancer

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How Flavin-containing monooxygenase 3 connects Entity context

The extracted context around Flavin-containing monooxygenase 3 shows recurring relationship patterns in the source. For example, Flavin-containing monooxygenase 3 → aortic valve, ascending aorta, bronchial epithelial cell, carotid body, lacrimal gland, mucosa of paranasal sinus, nasal epithelium, olfactory epithelium, olfactory zone of nasal mucosa, right lobe of liver, right lung, right lung lobe, right uterine tube, subcutaneous adipose tissue, superior surface of tongue, testicle, trachea, tunica media of zone of aorta, upper lobe of left lung, zygote Another extracted example is Flavin-containing monooxygenase 3 → endoplasmic reticulum, endoplasmic reticulum membrane, flavin adenine dinucleotide binding, integral component of membrane, intracellular membrane-bounded organelle, membrane, monooxygenase activity, N,N-dimethylaniline monooxygenase activity, NADP binding, organelle membrane, oxidoreductase activity, protein binding, trimethylamine monooxygenase activity, xenobiotic metabolic process. Use these groups to spot repeated connection types before inspecting the individual relationships.

Flavin-containing monooxygenase 3

Top relations

Bgee · 20
Flavin-containing monooxygenase 3 → aortic valve, ascending aorta, bronchial epithelial cell, carotid body, lacrimal gland, mucosa of paranasal sinus, nasal epithelium, olfactory epithelium, olfactory zone of nasal mucosa, right lobe of liver, right lung, right lung lobe, right uterine tube, subcutaneous adipose tissue, superior surface of tongue, testicle, trachea, tunica media of zone of aorta, upper lobe of left lung, zygote
RNA expression pattern · 20
Flavin-containing monooxygenase 3 → aortic valve, ascending aorta, bronchial epithelial cell, carotid body, lacrimal gland, mucosa of paranasal sinus, nasal epithelium, olfactory epithelium, olfactory zone of nasal mucosa, right lobe of liver, right lung, right lung lobe, right uterine tube, subcutaneous adipose tissue, superior surface of tongue, testicle, trachea, tunica media of zone of aorta, upper lobe of left lung, zygote
Gene ontology · 14
Flavin-containing monooxygenase 3 → endoplasmic reticulum, endoplasmic reticulum membrane, flavin adenine dinucleotide binding, integral component of membrane, intracellular membrane-bounded organelle, membrane, monooxygenase activity, N,N-dimethylaniline monooxygenase activity, NADP binding, organelle membrane, oxidoreductase activity, protein binding, trimethylamine monooxygenase activity, xenobiotic metabolic process
Band · 2
Flavin-containing monooxygenase 3 → 1 H2.1|1 70.34 cM, 1q24.3
Chr. · 2
Flavin-containing monooxygenase 3 → Chromosome 1 (human), Chromosome 1 (mouse)
End · 2
Flavin-containing monooxygenase 3 → 162,812,097 bp, 171,117,819 bp
1.14.13.148 · 1
Flavin-containing monooxygenase 3 → ↗
1.14.13.32 · 1
Flavin-containing monooxygenase 3 → ↗
1.14.13.8 · 1
Flavin-containing monooxygenase 3 → ↗
Aliases · 1
Flavin-containing monooxygenase 3 → FMO3, trimethylamine monooxygenase, flavin-containing monooxygenase 3, Dimethylaniline monooxygenase [N-oxide-forming] 3, FMOII, TMAU, dJ127D3.1, flavin containing monooxygenase…

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

fmo3 enzyme human bp monooxygenase trimethylamine also gene chr band primary catalyzes chromosome humans flavin-containing location known compounds dimethylaniline mouse

Flavin-containing monooxygenase 3 relationships Subject–Predicate–Object triples

TTTA extracted 78 structured relationships around Flavin-containing monooxygenase 3. Examples in this analysis include Flavin-containing monooxygenase 3 → 1.14.13.148 → ↗ and Flavin-containing monooxygenase 3 → Aliases → FMO3, trimethylamine monooxygenase, flavin-containing monooxygenase 3, Dimethylaniline monooxygenase [N-oxide-forming] 3, FMOII, TMAU, dJ127D3.1, flavin containing monooxygenase…. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Flavin-containing monooxygenase 31.14.13.148↗1.00infobox
Flavin-containing monooxygenase 31.14.13.32↗1.00infobox
Flavin-containing monooxygenase 31.14.13.8↗1.00infobox
Flavin-containing monooxygenase 3AliasesFMO3, trimethylamine monooxygenase, flavin-containing monooxygenase 3, Dimethylaniline monooxygenase [N-oxide-forming] 3, FMOII, TMAU, dJ127D3.1, flavin containing monooxygenase…1.00infobox
Flavin-containing monooxygenase 3Band1q24.31.00infobox
Flavin-containing monooxygenase 3Band1 H2.1|1 70.34 cM1.00infobox
Flavin-containing monooxygenase 3Bgeeright lobe of liver1.00infobox
Flavin-containing monooxygenase 3Bgeeolfactory zone of nasal mucosa1.00infobox
Flavin-containing monooxygenase 3Bgeenasal epithelium1.00infobox
Flavin-containing monooxygenase 3Bgeeright lung1.00infobox
Flavin-containing monooxygenase 3Bgeemucosa of paranasal sinus1.00infobox
Flavin-containing monooxygenase 3Bgeesubcutaneous adipose tissue1.00infobox
Flavin-containing monooxygenase 3Bgeebronchial epithelial cell1.00infobox
Flavin-containing monooxygenase 3Bgeeupper lobe of left lung1.00infobox
Flavin-containing monooxygenase 3Bgeeright uterine tube1.00infobox
Flavin-containing monooxygenase 3Bgeetesticle1.00infobox
Flavin-containing monooxygenase 3Bgeeright lung lobe1.00infobox
Flavin-containing monooxygenase 3Bgeetunica media of zone of aorta1.00infobox
Flavin-containing monooxygenase 3Bgeetrachea1.00infobox
Flavin-containing monooxygenase 3Bgeesuperior surface of tongue1.00infobox
Flavin-containing monooxygenase 3Bgeeolfactory epithelium1.00infobox
Flavin-containing monooxygenase 3Bgeeascending aorta1.00infobox
Flavin-containing monooxygenase 3Bgeeaortic valve1.00infobox
Flavin-containing monooxygenase 3Bgeezygote1.00infobox
Flavin-containing monooxygenase 3Bgeecarotid body1.00infobox
Flavin-containing monooxygenase 3Bgeelacrimal gland1.00infobox
Flavin-containing monooxygenase 3BioGPSMore reference expression data1.00infobox
Flavin-containing monooxygenase 3Chr.Chromosome 1 (human)1.00infobox
Flavin-containing monooxygenase 3Chr.Chromosome 1 (mouse)1.00infobox
Flavin-containing monooxygenase 3DatabasesNCBI: entry; OMA: entry1.00infobox

Related concept clusters Related term clusters

The concept neighborhoods around Flavin-containing monooxygenase 3 bring nearby vocabulary together. In this analysis, examples include Dimethylaniline, N-oxide-forming and Monooxygenase. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Flavin-containing monooxygenase 3
    • Dimethylaniline
    • N-oxide-forming
    • Monooxygenase
    • Enzyme
    • Humans
    • Gene
    • External
    • Trimethylamine
    • Fmo3
    • Activity
    • Expressed
    • Flavin
  • flavin-containing monooxygenase 3
    • Dimethylaniline
    • N-oxide-forming
    • Trimethylamine
    • Monooxygenase
    • Enzyme
    • Gene
    • Humans
    • Activity
    • Expressed
    • Flavin
    • Liver
    • External
  • flavin-containing monooxygenase
    • Dimethylaniline
    • N-oxide-forming
    • Trimethylamine
    • Monooxygenase
    • Enzyme
    • Gene
    • Humans
    • Activity
    • Expressed
    • Flavin
    • Liver
    • External
  • enzyme
    • Fmo3
    • Catalyzes
    • Flavin-containing
    • Humans
    • Primary
    • Monooxygenase
    • Trimethylamine
    • Known
    • N-oxide-forming
    • Gene
    • Human
    • External
  • monooxygenase
    • Trimethylamine
    • Gene
    • Activity
    • Expressed
    • Flavin
    • Liver
    • N-oxide-forming
    • Humans
    • Location
    • Chromosome
    • Bp
    • Chr
  • gene
    • Location
    • Chromosome
    • Activity
    • Bp
    • Chr
    • End
    • Flavin
    • H2
    • Human
    • Monooxygenase
    • Mouse
    • N-oxide-forming
  • human papillomavirus
    • Chromosome
    • Bp
    • Chr
    • Location
    • Band
    • Activity
    • End
    • Flavin
    • H2
    • Mouse
    • Monooxygenase
    • Trimethylamine
  • dimethylaniline
    • N-oxide-forming
    • Flavin-containing
    • External
    • Gene
    • Monooxygenase
    • Trimethylamine
    • Activity
    • Enzyme
    • Flavin
    • Known
    • Humans
    • Location

Connections between topic areas Semantic bridges

For Flavin-containing monooxygenase 3, one of the stronger structural bridges in this analysis connects Flavin-containing monooxygenase 3 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Flavin-containing monooxygenase 3 — Overview · splits 5 ⟂ 25
Flavin-containing monooxygenase 3 — Cancer · splits 26 ⟂ 4

Map overview Semantic statistics

Flavin-containing monooxygenase 3

Nodes30
Edges29
Triples78
Avg. degree1.93
Density0.066667
Components1

Source & methodology

TTTA analyzes the structure around Flavin-containing monooxygenase 3 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Overview & Cancer, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Flavin-containing monooxygenase 3 · EN edition · Analysis: TopicsToTalkAbout

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