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Fingolimod: History, Community, Culture & Applications

Fingolimod, sold under the brand name Gilenya, is an immunomodulating medication, used for the treatment of multiple sclerosis. Fingolimod is a sphingosine-1-phosphate receptor modulator, which sequesters lymphocytes in lymph nodes, preventing them from contributing to an autoimmune reaction. It has been reported to reduce the rate of relapses in…

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Fingolimod topic overview

The analysis highlights History, Community, Culture and Applications as prominent areas in the source structure around Fingolimod.

Related topics
45
Source areas
7
Connected nodes
52
Extracted relationships
63
Concept neighborhoods
15
Bridge connections
52

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Structure and mechanism · 18 topics
History · 12 topics
Adverse effects · 6 topics
Research · 4 topics
Overview · 3 topics
Medical uses · 1 topics
Society and culture · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
L04AE01 (WHO)
CAS Number
162359-55-9 N
ChEBI
CHEBI:63115 N
ChEMBL
ChEMBL314854 Y

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Adverse effects

Structure and mechanism

History

Society and culture

Research

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Fingolimod connects Entity context

The extracted context around Fingolimod shows recurring relationship patterns in the source. For example, Fingolimod → Chinese, Elimination, First, FTY720, Isaria, ISP-1, ISP-I, ISP-I-28, Myriocin, SAR, Showing, Structure, Yoshitomi Pharmaceuticals Another extracted example is Fingolimod → CD8, Isaria, ISP-1, It, Phospho-fingolimod, S1P, S1PR1, The, This, Unphosphorylated. Use these groups to spot repeated connection types before inspecting the individual relationships.

Fingolimod

Top relations

related to history · 13
Fingolimod → Chinese, Elimination, First, FTY720, Isaria, ISP-1, ISP-I, ISP-I-28, Myriocin, SAR, Showing, Structure, Yoshitomi Pharmaceuticals
related to Structure and mechanism · 10
Fingolimod → CD8, Isaria, ISP-1, It, Phospho-fingolimod, S1P, S1PR1, The, This, Unphosphorylated
has effect · 6
Fingolimod → At, It, The, Therefore, Two, Tysabri
Legal status · 5
Fingolimod → AU: S4 (Prescription only), CA: ℞-only, EU: Rx-only, UK: POM (Prescription only), US: ℞-only
related to Research · 3
Fingolimod → Clinical, Recently, S1P1
KEGG · 2
Fingolimod → as HCl: D04187, D10001 N
related to Medical uses · 2
Fingolimod → It, Its
3D model (JSmol) · 1
Fingolimod → Interactive image
AHFS/Drugs.com · 1
Fingolimod → Monograph
ATC code · 1
Fingolimod → L04AE01 (WHO)

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

multiple sclerosis drug also myriocin gilenya patients treatment reported used receptor lymphocytes may skin approved brain risk effective generic patent

Fingolimod relationships Subject–Predicate–Object triples

TTTA extracted 63 structured relationships around Fingolimod. Examples in this analysis include Fingolimod → 3D model (JSmol) → Interactive image and Fingolimod → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Fingolimod3D model (JSmol)Interactive image1.00infobox
FingolimodAHFS/Drugs.comMonograph1.00infobox
FingolimodATC codeL04AE01 (WHO)1.00infobox
FingolimodCAS Number162359-55-9 N1.00infobox
FingolimodChEBICHEBI:63115 N1.00infobox
FingolimodChEMBLChEMBL314854 Y1.00infobox
FingolimodChemSpider97087 Y1.00infobox
FingolimodCompTox Dashboard (EPA)DTXSID401673631.00infobox
FingolimodDrug classImmunosuppressants1.00infobox
FingolimodDrugBankDB08868 N1.00infobox
FingolimodFormulaC19H33NO21.00infobox
FingolimodIUPHAR/BPS24071.00infobox
FingolimodKEGGD10001 N1.00infobox
FingolimodKEGGas HCl: D041871.00infobox
FingolimodLegal statusAU: S4 (Prescription only)1.00infobox
FingolimodLegal statusCA: ℞-only1.00infobox
FingolimodLegal statusUK: POM (Prescription only)1.00infobox
FingolimodLegal statusUS: ℞-only1.00infobox
FingolimodLegal statusEU: Rx-only1.00infobox
FingolimodLicense dataUS DailyMed: Fingolimod1.00infobox
FingolimodMedlinePlusa6110061.00infobox
FingolimodMolar mass307.478 g·mol−11.00infobox
FingolimodPregnancy categoryAU: D1.00infobox
FingolimodPubChem CID1079701.00infobox
FingolimodRoutes of administrationBy mouth1.00infobox
FingolimodTrade namesGilenya1.00infobox
FingolimodUNII3QN8BYN5QF1.00infobox
Fingolimodcausesthe internalization of S1P receptors0.90text
Fingolimodis asphingosine-1-phosphate receptor modulator0.90text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Fingolimod bring nearby vocabulary together. In this analysis, examples include Also, Multiple and Sclerosis. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Fingolimod
    • Also
    • Multiple
    • Sclerosis
    • Cause
    • Receptor
    • Used
    • Treatment
    • Gilenya
    • Drug
    • Name
    • First
    • Infections
  • fingolimod
    • Also
    • Multiple
    • Sclerosis
    • Cause
    • Receptor
    • Used
    • Treatment
    • Gilenya
    • Drug
    • Name
    • First
    • Infections
  • multiple sclerosis
    • Sclerosis
    • Treatment
    • Relapses
    • Relapsing
    • Used
    • Name
    • Drug
    • Reduce
    • Approved
    • Effective
    • Reported
    • Patients
  • food and drug administration
    • Approved
    • Patients
    • Reduce
    • Relapsing
    • Multiple
    • Sclerosis
    • Reported
    • Also
    • Fingolimod
    • Legal
    • Status
    • Name
  • relapsing-remitting multiple sclerosis
    • Sclerosis
    • Treatment
    • Relapses
    • Relapsing
    • Used
    • Name
    • Drug
    • Reduce
    • Approved
    • Effective
    • Reported
    • Patients
  • skin graft
    • Cancer
    • Cases
    • Risks
    • Serious
    • Approved
    • Effective
    • Reported
    • Myriocin
    • Patients
    • Also
    • Drug
    • Multiple
  • breast cancer
    • Skin
    • Patients
    • Cases
    • Risks
    • Serious
    • Approved
    • Reported
    • Drug
    • Multiple
    • Sclerosis
  • progressive multifocal leukoencephalopathy
    • Cases
    • Infection
    • Brain
    • Reported
    • Patients
    • Also
    • Sclerosis

Connections between topic areas Semantic bridges

For Fingolimod, one of the stronger structural bridges in this analysis connects Fingolimod with Structure and mechanism. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Fingolimod — Structure and mechanism · splits 34 ⟂ 19
Fingolimod — History · splits 40 ⟂ 13
Fingolimod — Adverse effects · splits 46 ⟂ 7
Fingolimod — Research · splits 48 ⟂ 5
Fingolimod — Overview · splits 49 ⟂ 4

Map overview Semantic statistics

Fingolimod

Nodes53
Edges52
Triples63
Avg. degree1.96
Density0.037736
Components1

Source & methodology

TTTA analyzes the structure around Fingolimod to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Community, Culture & Applications, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Fingolimod · EN edition · Analysis: TopicsToTalkAbout

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