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FIGLA

Folliculogenesis-specific basic helix-loop-helix, also known as factor in the germline alpha (FIGalpha) or transcription factor FIGa, is a protein that in humans is encoded by the FIGLA gene. The FIGLA gene is a germ cell-specific transcription factor preferentially expressed in oocytes that can be found on human chromosome 2p13.3.

Function, Clinical significance & Overview

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Function

4 related topics

Clinical significance

1 related topics

Overview

2 related topics

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Aliases
FIGLA, BHLHC8, FIGALPHA, POF6, folliculogenesis specific bHLH transcription factor
Band
2p13.3 · 6|6 C3
Bgee
oocyte · secondary oocyte · testicle · gonad · body of pancreas
BioGPS
n/a
Chr.
Chromosome 2 (human) · Chromosome 6 (mouse)
Databases
NCBI: entry; OMA: entry

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Overview

Function

Clinical significance

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Map overview Semantic statistics

FIGLA

Nodes11
Edges10
Triples89
Avg. degree1.82
Density0.181818
Components1

How this topic connects Entity context

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FIGLA

Top relations

Bgee · 19
FIGLA → abdominal wall, body of pancreas, body of uterus, embryo, gastric mucosa, gonad, lens, myometrium, oocyte, ovarian follicle cell, primary follicle of ovary, primary oocyte, right ovary, secondary follicle of ovary, secondary oocyte, spermatid, spermatocyte, testicle, zygote
RNA expression pattern · 19
FIGLA → abdominal wall, body of pancreas, body of uterus, embryo, gastric mucosa, gonad, lens, myometrium, oocyte, ovarian follicle cell, primary follicle of ovary, primary oocyte, right ovary, secondary follicle of ovary, secondary oocyte, spermatid, spermatocyte, testicle, zygote
Gene ontology · 17
FIGLA → cell differentiation, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, RNA polymerase II-specific, multicellular organism development, nucleus, oocyte development, oogenesis, positive regulation of transcription by RNA polymerase II, protein dimerization activity, regulation of transcription, DNA-templated, RNA polymerase II cis-regulatory region sequence-specific DNA binding, sequence-specific DNA binding, transcription by RNA polymerase II, transcription factor binding, transcription regulator complex, transcription, DNA-templated
related to Clinical significance · 9
FIGLA → As, It, Mutation, Premature, This, Women, Zp1, Zp2, ZP3
related to Function · 5
FIGLA → The, This, ZP1, ZP2, ZP3
Band · 2
FIGLA → 2p13.3, 6|6 C3
Chr. · 2
FIGLA → Chromosome 2 (human), Chromosome 6 (mouse)
End · 2
FIGLA → 70,790,643 bp, 85,997,978 bp
Aliases · 1
FIGLA → FIGLA, BHLHC8, FIGALPHA, POF6, folliculogenesis specific bHLH transcription factor
BioGPS · 1
FIGLA → n/a

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Important terminology

gene human bp factor transcription chromosome chr band protein ovarian failure location oocyte premature mouse expression figalpha expressed 2p13 function

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
FIGLAAliasesFIGLA, BHLHC8, FIGALPHA, POF6, folliculogenesis specific bHLH transcription factor1.00infobox
FIGLABand2p13.31.00infobox
FIGLABand6|6 C31.00infobox
FIGLABgeeoocyte1.00infobox
FIGLABgeesecondary oocyte1.00infobox
FIGLABgeetesticle1.00infobox
FIGLABgeegonad1.00infobox
FIGLABgeebody of pancreas1.00infobox
FIGLABgeegastric mucosa1.00infobox
FIGLABgeemyometrium1.00infobox
FIGLABgeeabdominal wall1.00infobox
FIGLABgeebody of uterus1.00infobox
FIGLABgeeright ovary1.00infobox
FIGLABgeeprimary oocyte1.00infobox
FIGLABgeeembryo1.00infobox
FIGLABgeeovarian follicle cell1.00infobox
FIGLABgeesecondary follicle of ovary1.00infobox
FIGLABgeezygote1.00infobox
FIGLABgeelens1.00infobox
FIGLABgeeprimary follicle of ovary1.00infobox
FIGLABgeespermatid1.00infobox
FIGLABgeespermatocyte1.00infobox
FIGLABioGPSn/a1.00infobox
FIGLAChr.Chromosome 2 (human)1.00infobox
FIGLAChr.Chromosome 6 (mouse)1.00infobox
FIGLADatabasesNCBI: entry; OMA: entry1.00infobox
FIGLAEnd70,790,643 bp1.00infobox
FIGLAEnd85,997,978 bp1.00infobox
FIGLAEnsemblENSG000001837331.00infobox
FIGLAEntrez3440181.00infobox

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