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Fibulin: Genes & Overview

Fibulin (FY-beau-lin) (now known as Fibulin-1 FBLN1) is the prototypic member of a multigene family, currently with seven members. Fibulin-1 is a calcium-binding glycoprotein. In vertebrates, fibulin-1 is found in blood and extracellular matrices. In the extracellular matrix, fibulin-1 associates with basement membranes and elastic fibers. The…

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Fibulin topic overview

The analysis highlights Genes and Overview as prominent areas in the source structure around Fibulin.

Related topics
19
Source areas
2
Connected nodes
21
Extracted relationships
20
Related term clusters
16
Bridge connections
21

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 14 topics
Genes · 5 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

AlphaFold
IPR000020 · PF01821
Available protein structures:
IPR000020 · PF01821
CDD
cd00017
InterPro
IPR000020
PDB
2a73B:693-728 1c5a :21-55 1cfaA:698-732 1kjs :698-732 IPR000020 PF01821 (ECOD; PDBsum)
Pfam
PF01821

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Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Genes

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How Fibulin connects Entity context

The extracted context around Fibulin shows recurring relationship patterns in the source. For example, Fibulin → FBLN1, FBLN2, FBLN3, FBLN4, FBLN5, FBLN7, HMCN1 Another extracted example is Fibulin → IPR000020, PF01821. Use these groups to spot repeated connection types before inspecting the individual relationships.

Fibulin

Top relations

related to Genes · 7
Fibulin → FBLN1, FBLN2, FBLN3, FBLN4, FBLN5, FBLN7, HMCN1
AlphaFold · 2
Fibulin → IPR000020, PF01821
Available protein structures: · 2
Fibulin → IPR000020, PF01821
CDD · 1
Fibulin → cd00017
InterPro · 1
Fibulin → IPR000020
PDB · 1
Fibulin → 2a73B:693-728 1c5a :21-55 1cfaA:698-732 1kjs :698-732 IPR000020 PF01821 (ECOD; PDBsum)
Pfam · 1
Fibulin → PF01821
PROSITE · 1
Fibulin → PDOC00906
SCOP2 · 1
Fibulin → 1c5a / SCOPe / SUPFAM
SMART · 1
Fibulin → ANATO

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

fibulin-1 extracellular matrix structure structures known blood fibronectin proteoglycans tropoelastin family members calcium-binding found sites three fbln1 glycoprotein cell domain

Fibulin relationships Subject–Predicate–Object triples

TTTA extracted 20 structured relationships around Fibulin. Examples in this analysis include Fibulin → AlphaFold → IPR000020 and Fibulin → AlphaFold → PF01821. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
FibulinAlphaFoldIPR0000201.00infobox
FibulinAlphaFoldPF018211.00infobox
FibulinAvailable protein structures:IPR0000201.00infobox
FibulinAvailable protein structures:PF018211.00infobox
FibulinCDDcd000171.00infobox
FibulinInterProIPR0000201.00infobox
FibulinPDB2a73B:693-728 1c5a :21-55 1cfaA:698-732 1kjs :698-732 IPR000020 PF01821 (ECOD; PDBsum)1.00infobox
FibulinPfamPF018211.00infobox
FibulinPROSITEPDOC009061.00infobox
FibulinSCOP21c5a / SCOPe / SUPFAM1.00infobox
FibulinSMARTANATO1.00infobox
FibulinSymbolANATO1.00infobox
Fibulinis aextracellular matrix and plasma glycoprotein with repeated domain structure0.90text

Related concept clusters Related term clusters

The concept neighborhoods around Fibulin bring nearby vocabulary together. In this analysis, examples include Domain, Currently and Fy-beau-lin. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • fibulin-1
    • Blood
    • Extracellular
    • Associates
    • Basement
    • Elastic
    • Fibers
    • Fibrinogen
    • Fy-beau-lin
    • Matrices
    • Member
    • Membranes
    • Multigene
  • extracellular matrices
    • Vertebrates
    • Matrix
    • Fibulin-1
    • Associates
    • Basement
    • Elastic
    • Fibers
    • Laminins
    • Matrices
    • Membranes
    • Cell
    • Domain
  • Fibulin
    • Domain
    • Currently
    • Fy-beau-lin
    • Member
    • Multigene
    • Now
    • Prototypic
    • Seven
    • Family
    • Fbln1
    • Glycoprotein
    • Members
  • fibulin
    • Domain
    • Currently
    • Fy-beau-lin
    • Member
    • Multigene
    • Now
    • Prototypic
    • Seven
    • Family
    • Fbln1
    • Glycoprotein
    • Members
  • fbln1
    • Known
    • Currently
    • Fy-beau-lin
    • Member
    • Multigene
    • Now
    • Prototypic
    • Seven
    • Family
    • Members
    • Structures
    • Fibulin
  • calcium-binding glycoprotein
    • Family
    • Glycoprotein
    • Members
    • Sites
    • Known
    • Matrix
    • Structure
    • Fibulin-1
  • basement membranes
    • Associates
    • Basement
    • Elastic
    • Fibers
    • Membranes
    • Matrix
    • Extracellular
    • Fibulin-1
  • tropoelastin
    • Fibronectin
    • Proteoglycans
    • Structures
    • Laminins
    • Sites
    • Matrix
    • Extracellular

Connections between topic areas Semantic bridges

For Fibulin, one of the stronger structural bridges in this analysis connects Fibulin with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Fibulin — Overview · splits 7 ⟂ 15
Fibulin — Genes · splits 16 ⟂ 6

Map overview Semantic statistics

Fibulin

Nodes22
Edges21
Triples20
Avg. degree1.91
Density0.090909
Components1

Source & methodology

TTTA analyzes the structure around Fibulin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Genes & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Fibulin · EN edition · Analysis: TopicsToTalkAbout

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