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Fibroblast growth factor 1

Fibroblast growth factor 1 (FGF-1) also known as acidic fibroblast growth factor (aFGF), is a growth factor and signaling protein encoded by the FGF1 gene. It is synthesized as a 155 amino acid polypeptide, whose mature form is a non-glycosylated 17-18 kDa protein. Fibroblast growth factor protein was first purified in 1975, but soon afterwards others…

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Aliases
FGF1, AFGF, ECGF, ECGF-beta, ECGFA, ECGFB, FGF-1, FGF-alpha, FGFA, GLIO703, HBGF-1, HBGF1, fibroblast growth factor 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4QO3, 1AXM, 1DJS, 1DZC, 1DZD, 1E0O, 1EVT, 1HKN, 1JQZ, 1JT3, 1JT4, 1JT5, 1JT7, 1JTC, 1JY0, 1K5U, 1K5V, 1M16,…
Band
5q31.3 · 18 B3|18 20.74 cM
Bgee
glomerulus · metanephric glomerulus · inferior ganglion of vagus nerve · corpus callosum · optic nerve
BioGPS
More reference expression data
Chr.
Chromosome 5 (human) · Chromosome 18 (mouse)

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Fibroblast growth factor 1

Nodes35
Edges34
Triples114
Avg. degree1.94
Density0.057143
Components1

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Fibroblast growth factor 1

Top relations

Gene ontology · 51
Fibroblast growth factor 1 → 1-phosphatidylinositol-3-kinase activity, activation of protein kinase B activity, anatomical structure morphogenesis, angiogenesis, branch elongation involved in ureteric bud branching, cell cortex, cell differentiation, cell population proliferation, cellular response to heat, cytoplasm, cytosol, extracellular matrix, extracellular region, extracellular space, fibroblast growth factor receptor binding, fibroblast growth factor receptor signaling pathway, growth factor activity, heparin binding, Hsp70 protein binding, integrin binding
Bgee · 20
Fibroblast growth factor 1 → anterior horn of spinal cord, corpus callosum, deep cerebellar nuclei, dorsal tegmental nucleus, external globus pallidus, facial motor nucleus, glomerulus, habenula, inferior ganglion of vagus nerve, inferior olivary nucleus, internal globus pallidus, medial vestibular nucleus, medulla oblongata, metanephric glomerulus, myocardium of ventricle, olfactory bulb, optic nerve, pontine nuclei, right lung, right ventricle
RNA expression pattern · 20
Fibroblast growth factor 1 → anterior horn of spinal cord, corpus callosum, deep cerebellar nuclei, dorsal tegmental nucleus, external globus pallidus, facial motor nucleus, glomerulus, habenula, inferior ganglion of vagus nerve, inferior olivary nucleus, internal globus pallidus, medial vestibular nucleus, medulla oblongata, metanephric glomerulus, myocardium of ventricle, olfactory bulb, optic nerve, pontine nuclei, right lung, right ventricle
Band · 2
Fibroblast growth factor 1 → 18 B3|18 20.74 cM, 5q31.3
Chr. · 2
Fibroblast growth factor 1 → Chromosome 18 (mouse), Chromosome 5 (human)
End · 2
Fibroblast growth factor 1 → 142,698,070 bp, 39,062,525 bp
Aliases · 1
Fibroblast growth factor 1 → FGF1, AFGF, ECGF, ECGF-beta, ECGFA, ECGFB, FGF-1, FGF-alpha, FGFA, GLIO703, HBGF-1, HBGF1, fibroblast growth factor 1
Available structures · 1
Fibroblast growth factor 1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4QO3, 1AXM, 1DJS, 1DZC, 1DZD, 1E0O, 1EVT, 1HKN, 1JQZ, 1JT3, 1JT4, 1JT5, 1JT7, 1JTC, 1JY0, 1K5U, 1K5V, 1M16,…
BioGPS · 1
Fibroblast growth factor 1 → More reference expression data
Databases · 1
Fibroblast growth factor 1 → NCBI: entry; OMA: entry

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Important terminology

fgf1 protein growth factor cell fibroblast gene bp also chr human band chromosome proteins nucleus fgf-1 binding extracellular receptor function

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Fibroblast growth factor 1AliasesFGF1, AFGF, ECGF, ECGF-beta, ECGFA, ECGFB, FGF-1, FGF-alpha, FGFA, GLIO703, HBGF-1, HBGF1, fibroblast growth factor 11.00infobox
Fibroblast growth factor 1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4QO3, 1AXM, 1DJS, 1DZC, 1DZD, 1E0O, 1EVT, 1HKN, 1JQZ, 1JT3, 1JT4, 1JT5, 1JT7, 1JTC, 1JY0, 1K5U, 1K5V, 1M16,…1.00infobox
Fibroblast growth factor 1Band5q31.31.00infobox
Fibroblast growth factor 1Band18 B3|18 20.74 cM1.00infobox
Fibroblast growth factor 1Bgeeglomerulus1.00infobox
Fibroblast growth factor 1Bgeemetanephric glomerulus1.00infobox
Fibroblast growth factor 1Bgeeinferior ganglion of vagus nerve1.00infobox
Fibroblast growth factor 1Bgeecorpus callosum1.00infobox
Fibroblast growth factor 1Bgeeoptic nerve1.00infobox
Fibroblast growth factor 1Bgeeexternal globus pallidus1.00infobox
Fibroblast growth factor 1Bgeeinternal globus pallidus1.00infobox
Fibroblast growth factor 1Bgeemedulla oblongata1.00infobox
Fibroblast growth factor 1Bgeeinferior olivary nucleus1.00infobox
Fibroblast growth factor 1Bgeeolfactory bulb1.00infobox
Fibroblast growth factor 1Bgeedeep cerebellar nuclei1.00infobox
Fibroblast growth factor 1Bgeepontine nuclei1.00infobox
Fibroblast growth factor 1Bgeemedial vestibular nucleus1.00infobox
Fibroblast growth factor 1Bgeehabenula1.00infobox
Fibroblast growth factor 1Bgeefacial motor nucleus1.00infobox
Fibroblast growth factor 1Bgeedorsal tegmental nucleus1.00infobox
Fibroblast growth factor 1Bgeeanterior horn of spinal cord1.00infobox
Fibroblast growth factor 1Bgeeright lung1.00infobox
Fibroblast growth factor 1Bgeemyocardium of ventricle1.00infobox
Fibroblast growth factor 1Bgeeright ventricle1.00infobox
Fibroblast growth factor 1BioGPSMore reference expression data1.00infobox
Fibroblast growth factor 1Chr.Chromosome 5 (human)1.00infobox
Fibroblast growth factor 1Chr.Chromosome 18 (mouse)1.00infobox
Fibroblast growth factor 1DatabasesNCBI: entry; OMA: entry1.00infobox
Fibroblast growth factor 1End142,698,070 bp1.00infobox
Fibroblast growth factor 1End39,062,525 bp1.00infobox

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