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Fibroblast

A fibroblast is a type of biological cell typically with a spindle shape that synthesizes the extracellular matrix and collagen, produces the structural framework (stroma) for animal tissues, and plays a critical role in wound healing. Fibroblasts are the most common cells of connective tissue in animals.

Cultures, Structure & Function

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Key facts & relationships

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Location
Connective tissue
FMA
63877
Function
Extracellular matrix and collagen creation
Latin
fibroblastus
MeSH
D005347
TH
H2.00.03.0.01002

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Map overview Semantic statistics

Fibroblast

Nodes46
Edges45
Triples60
Avg. degree1.96
Density0.043478
Components1

How this topic connects Entity context

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Fibroblast

Top relations

related to Tumour mediation · 15
Fibroblast → Although, Cleaved ECM, ECM, Examples, Fibroblasts, Immune, In, Proteases, TAF, TAF-derived, TAF-derived ECM, Tenascin, These, Thrombospondin-1, TSP-1
related to Structure · 7
Fibroblast → Active, Although, Fibroblasts, Inactive, RER, Unlike, While
related to Use of fibroblasts as feeder cells · 6
Fibroblast → However, In, MEF, MEFs, Mouse, Whereas
related to Development · 5
Fibroblast → ECM, Hence, However, Like, The
related to Relationship with fibrocytes · 5
Fibroblast → Currently, Fibroblasts, The, This, Though
related to Host immune response · 4
Fibroblast → Fibroblasts, In, The, These
related to Inflammation · 4
Fibroblast → Besides, Immune, Receptors, They
related to Function · 3
Fibroblast → Fibroblasts, The, Tissue
FMA · 1
Fibroblast → 63877
Function · 1
Fibroblast → Extracellular matrix and collagen creation

Important terminology Word statistics

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Important terminology

fibroblasts cells immune epithelial ecm tissue connective components also cell tissues may structural response matrix collagen regulation taf-derived role development

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
FibroblastFMA638771.00infobox
FibroblastFunctionExtracellular matrix and collagen creation1.00infobox
FibroblastLatinfibroblastus1.00infobox
FibroblastLocationConnective tissue1.00infobox
FibroblastMeSHD0053471.00infobox
FibroblastTHH2.00.03.0.010021.00infobox
Fibroblastis atype of biological cell typically with a spindle shape that synthesizes the extracellular matrix and collagen0.90text
cardiomyocytes.Host immune responseFibroblasts from different anatomical sites in the body express many genes that code for immune mediatorsinstance ofthey can also be used to facilitate development of the stem cells into specific type of cells0.80text
proteinsinstance ofthey can also be used to facilitate development of the stem cells into specific type of cells0.80text
cardiomyocytesinstance ofthey can also be used to facilitate development of the stem cells into specific type of cells0.80text
Fibroblastrelated to DevelopmentThe0.60section
Fibroblastrelated to DevelopmentECM0.60section

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