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Erdosteine

Erdosteine is a molecule with mucolytic activity. Structurally it is a thioether derivative with two thioether groups. These two functional organosulfur groups contained in the molecule are released following first-pass metabolism with the conversion of erdosteine into its pharmacologically active metabolite Met-I (N-thiodiglycolyl-homocysteine).

Applications, Pharmacodynamics & Safety profile

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Pharmacodynamics

Anti-oxidantOxidative stressInflammationAntibioticsAnti-inflammatory
21 related topics

Safety profile

HydrolysisHeadacheDyspneaNauseaVomiting
7 related topics

Contraindications

ExcipientsHepatic cirrhosisEnzyme
3 related topics

Pharmacokinetics

Pharmacokinetic
1 related topics

Key facts & relationships

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
International Drug Names
ATC code
R05CB15 (WHO)
CAS Number
84611-23-4 Y
ChEMBL
ChEMBL1697744
ChemSpider
59073 Y

Topics to explore

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Overview

Pharmacodynamics

Pharmacokinetics

Clinical uses

Safety profile

Contraindications

Interaction with other medicinal products

Advanced semantic analysis

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Map overview Semantic statistics

Erdosteine

Nodes45
Edges44
Triples44
Avg. degree1.96
Density0.044444
Components1

How this topic connects Entity context

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Erdosteine

Top relations

related to Clinical uses · 4
Erdosteine → Chronic Obstructive Pulmonary Disease, Clinical, COPD, It
related to Other activities · 4
Erdosteine → Countries, In, Otitis Media Secretorica, Several
related to Anti-oxidant and anti-inflammatory activity · 3
Erdosteine → COPD, Met, ROS
related to Antiadhesive activity · 3
Erdosteine → In, Met, The
related to Chronic Obstructive Pulmonary Disease · 3
Erdosteine → COPD, Evidence, These
related to Pharmacokinetics · 3
Erdosteine → Food, Met, The
related to Mucolytic activity · 2
Erdosteine → N-acetylcysteine, Several
related to Safety profile · 2
Erdosteine → Data, Frequency
3D model (JSmol) · 1
Erdosteine → Interactive image
AHFS/Drugs.com · 1
Erdosteine → International Drug Names

Important terminology Word statistics

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Important terminology

patients chronic copd exacerbations treatment mucolytic met respiratory molecule active oral activity drug mucus several mg clinical profile metabolism antibiotics

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Erdosteine3D model (JSmol)Interactive image1.00infobox
ErdosteineAHFS/Drugs.comInternational Drug Names1.00infobox
ErdosteineATC codeR05CB15 (WHO)1.00infobox
ErdosteineCAS Number84611-23-4 Y1.00infobox
ErdosteineChEMBLChEMBL16977441.00infobox
ErdosteineChemSpider59073 Y1.00infobox
ErdosteineCompTox Dashboard (EPA)DTXSID80487351.00infobox
ErdosteineECHA InfoCard100.169.9841.00infobox
ErdosteineElimination half-life1–3 hours1.00infobox
ErdosteineFormulaC8H11NO4S21.00infobox
ErdosteineKEGGD07383 Y1.00infobox
ErdosteineMetabolismliver1.00infobox
ErdosteineMolar mass249.30 g·mol−11.00infobox
ErdosteineProtein binding65%1.00infobox
ErdosteinePubChem CID656321.00infobox
ErdosteineRoutes of administrationBy mouth, inhalation1.00infobox
ErdosteineUNII76J0853EKA1.00infobox
Erdosteineis amolecule with mucolytic activity0.90text

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