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Cetuximab

Cetuximab, sold under the brand name Erbitux, is an epidermal growth factor receptor (EGFR) inhibitor medication used for the treatment of metastatic colorectal cancer and head and neck cancer. Cetuximab is a chimeric (mouse/human) monoclonal antibody given by intravenous infusion.

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Explore the main themes, entities and connections around Cetuximab. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Key facts & relationships

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AHFS/Drugs.com
Monograph
ATC code
L01FE01 (WHO)
CAS Number
205923-56-4 Y
ChEMBL
ChEMBL1201577 N
ChemSpider
none
CompTox Dashboard (EPA)
DTXSID0040830

Topics to explore

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Overview

Medical uses

Side effects

KRAS Testing

History

Society and culture

Research

Advanced semantic analysis

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Map overview Semantic statistics

Cetuximab

Nodes47
Edges46
Triples85
Avg. degree1.96
Density0.042553
Components1

How this topic connects Entity context

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Cetuximab

Top relations

related to Head and neck cancer · 12
Cetuximab → De-ESCALaTE HPV, Drug Administration, FDA, However, HPV, III, IMCL-9815, In, March, NRG Oncology RTOG, SCCHN, US Food
related to Insider trading · 11
Cetuximab → FDA, ImClone, Martha Stewart, Merrill Lynch, Peter Bacanovic, Prior, Samuel, SEC, Stewart's, This, Waksal
related to KRAS Testing · 9
Cetuximab → Drug Administration, EGFR, Erbitux, FDA, In July, KRAS, The KRAS, US Food, Vectibix
Legal status · 5
Cetuximab → AU: S4 (Prescription only), CA: ℞-only, EU: Rx-only, UK: POM (Prescription only), US: ℞-only
related to Colorectal cancer · 5
Cetuximab → Drug Administration, FDA, Food, In July, KRAS
related to Medical uses · 5
Cetuximab → EGFR, EU, In, RAS, US
related to Research · 5
Cetuximab → III, OS, The, University College London, With
has effect · 4
Cetuximab → Further, It, One, Other
related to Alpha-gal allergy · 4
Cetuximab → Certain, Fewer, This, United States
related to Economics · 3
Cetuximab → Bristol-Myers Squibb, Erbitux, Merck KGaA

Important terminology Word statistics

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Important terminology

cancer erbitux kras egfr treatment colorectal head neck receptor antibody indicated drug merck metastatic use chimeric mouse human intravenous medical

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
CetuximabAHFS/Drugs.comMonograph1.00infobox
CetuximabATC codeL01FE01 (WHO)1.00infobox
CetuximabCAS Number205923-56-4 Y1.00infobox
CetuximabChEMBLChEMBL1201577 N1.00infobox
CetuximabChemSpidernone1.00infobox
CetuximabCompTox Dashboard (EPA)DTXSID00408301.00infobox
CetuximabDrugBankDB00002 Y1.00infobox
CetuximabElimination half-life114 hrs1.00infobox
CetuximabFormulaC6484H10042N1732O2023S361.00infobox
CetuximabKEGGD03455 Y1.00infobox
CetuximabLegal statusAU: S4 (Prescription only)1.00infobox
CetuximabLegal statusCA: ℞-only1.00infobox
CetuximabLegal statusUK: POM (Prescription only)1.00infobox
CetuximabLegal statusUS: ℞-only1.00infobox
CetuximabLegal statusEU: Rx-only1.00infobox
CetuximabLicense dataUS DailyMed: Cetuximab1.00infobox
CetuximabMolar mass145781.92 g·mol−11.00infobox
CetuximabPregnancy categoryAU: D1.00infobox
CetuximabRoutes of administrationIntravenous1.00infobox
CetuximabSourceChimeric (mouse/human)1.00infobox
CetuximabTargetEGF receptor1.00infobox
CetuximabTrade namesErbitux1.00infobox
CetuximabTypeWhole antibody1.00infobox
CetuximabUNIIPQX0D8J21J1.00infobox
Cetuximabis achimeric0.90text

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