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Epsin

Epsins are a family of highly conserved membrane proteins that are important in creating membrane curvature. Epsins contribute to membrane deformations like endocytosis, and block vesicle formation during mitosis.

Members, Structure & Function

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Overview

Structure

Function

Family members

Clinical significance

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Map overview Semantic statistics

Epsin

Nodes38
Edges37
Triples45
Avg. degree1.95
Density0.052632
Components1

How this topic connects Entity context

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Epsin

Top relations

related to Structure · 13
Epsin → Additionally, AP2, C-terminus, DP, ENTH, Epsin N-Terminal Homolog, Following, However, It, N-terminus, Starting, The, The ENTH
related to Function · 12
Epsin → AP2, As, At, ENTH, Epsins, In, It, N-terminus, Swiss, The, The C-terminus, UIMs
related to Family members · 9
Epsin → ENTH, EPN-1, EPN1, EPN2, EPN3, EPN4, The, There, UIM
related to Clinical significance · 6
Epsin → CLINT1, Research, Several, SNPs, There, Wnt
related to External links · 3
Epsin → Developmental Biology, Endocytosis, Liquid

Important terminology Word statistics

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Important terminology

domain epsins enth role notch membrane clathrin endocytosis signaling family two members vesicle conserved proteins domains bind thought motifs evidence

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
the clathrin-binding motifs which bind clathrin heavy chaininstance ofin higher eukaryotes there are several conserved motifs0.80text
these motifs flank a cluster of up to eight DP repeats which bind to AP2instance ofin higher eukaryotes there are several conserved motifs0.80text
Epsinrelated to Clinical significanceSeveral0.60section
Epsinrelated to Clinical significanceResearch0.60section
Epsinrelated to Clinical significanceThere0.60section
Epsinrelated to Clinical significanceWnt0.60section
Epsinrelated to Clinical significanceCLINT10.60section
Epsinrelated to Clinical significanceSNPs0.60section
Epsinrelated to External linksEndocytosis0.60section
Epsinrelated to External linksDevelopmental Biology0.60section
Epsinrelated to External linksLiquid0.60section
Epsinrelated to Family membersThere0.60section

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