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EPS15: Interactions, Function & Overview

Epidermal growth factor receptor substrate 15 is a protein that in humans is encoded by the EPS15 gene.

Language: English [EN]
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EPS15 topic overview

The analysis highlights Interactions, Function and Overview as prominent areas in the source structure around EPS15.

Related topics
9
Source areas
3
Connected nodes
12
Extracted relationships
110
Concept neighborhoods
6
Bridge connections
12

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 6 topics
Overview · 2 topics
Function · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
EPS15, AF-1P, AF1P, MLLT5, epidermal growth factor receptor pathway substrate 15
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1C07, 1EH2, 1F8H, 1FF1, 2IV9, 2JXC, 4RH5, 4RH9, 4RHG, 4S0G, 5JP2
Band
1p32.3 · 4|4 C7
Bgee
endothelial cell · sperm · internal globus pallidus · frontal pole · Brodmann area 23
BioGPS
More reference expression data
Chr.
Chromosome 1 (human) · Chromosome 4 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How EPS15 connects Entity context

The extracted context around EPS15 shows recurring relationship patterns in the source. For example, EPS15 → aggresome, AP-2 adaptor complex, apical plasma membrane, basal plasma membrane, cadherin binding, calcium ion binding, cargo receptor activity, cell population proliferation, ciliary membrane, clathrin coat assembly, clathrin coat of coated pit, clathrin-coated pit, clathrin-coated vesicle, cytoplasm, cytosol, early endosome, early endosome membrane, endocytic recycling, endocytosis, endosome Another extracted example is EPS15 → Brodmann area 23, cerebellar vermis, cingulate gyrus, corpus callosum, deep cerebellar nuclei, endothelial cell, frontal pole, internal globus pallidus, lateral geniculate nucleus, lateral nuclear group of thalamus, lobe of cerebellum, middle temporal gyrus, pars compacta, pons, pontine nuclei, Region I of hippocampus proper, sciatic nerve, sperm, substantia nigra, ventral tegmental area. Use these groups to spot repeated connection types before inspecting the individual relationships.

EPS15

Top relations

Gene ontology · 44
EPS15 → aggresome, AP-2 adaptor complex, apical plasma membrane, basal plasma membrane, cadherin binding, calcium ion binding, cargo receptor activity, cell population proliferation, ciliary membrane, clathrin coat assembly, clathrin coat of coated pit, clathrin-coated pit, clathrin-coated vesicle, cytoplasm, cytosol, early endosome, early endosome membrane, endocytic recycling, endocytosis, endosome
Bgee · 20
EPS15 → Brodmann area 23, cerebellar vermis, cingulate gyrus, corpus callosum, deep cerebellar nuclei, endothelial cell, frontal pole, internal globus pallidus, lateral geniculate nucleus, lateral nuclear group of thalamus, lobe of cerebellum, middle temporal gyrus, pars compacta, pons, pontine nuclei, Region I of hippocampus proper, sciatic nerve, sperm, substantia nigra, ventral tegmental area
RNA expression pattern · 20
EPS15 → Brodmann area 23, cerebellar vermis, cingulate gyrus, corpus callosum, deep cerebellar nuclei, endothelial cell, frontal pole, internal globus pallidus, lateral geniculate nucleus, lateral nuclear group of thalamus, lobe of cerebellum, middle temporal gyrus, pars compacta, pons, pontine nuclei, Region I of hippocampus proper, sciatic nerve, sperm, substantia nigra, ventral tegmental area
related to Interactions · 3
EPS15 → CRKEPN1, HGS, HRB
Band · 2
EPS15 → 1p32.3, 4|4 C7
Chr. · 2
EPS15 → Chromosome 1 (human), Chromosome 4 (mouse)
End · 2
EPS15 → 109,245,014 bp, 51,519,266 bp
Aliases · 1
EPS15 → EPS15, AF-1P, AF1P, MLLT5, epidermal growth factor receptor pathway substrate 15
Available structures · 1
EPS15 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1C07, 1EH2, 1F8H, 1FF1, 2IV9, 2JXC, 4RH5, 4RH9, 4RHG, 4S0G, 5JP2
BioGPS · 1
EPS15 → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene bp chr human band chromosome protein epidermal growth factor receptor location pathway mouse substrate 15 function search 519 266

EPS15 relationships Subject–Predicate–Object triples

TTTA extracted 110 structured relationships around EPS15. Examples in this analysis include EPS15 → Aliases → EPS15, AF-1P, AF1P, MLLT5, epidermal growth factor receptor pathway substrate 15 and EPS15 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1C07, 1EH2, 1F8H, 1FF1, 2IV9, 2JXC, 4RH5, 4RH9, 4RHG, 4S0G, 5JP2. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
EPS15AliasesEPS15, AF-1P, AF1P, MLLT5, epidermal growth factor receptor pathway substrate 151.00infobox
EPS15Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1C07, 1EH2, 1F8H, 1FF1, 2IV9, 2JXC, 4RH5, 4RH9, 4RHG, 4S0G, 5JP21.00infobox
EPS15Band1p32.31.00infobox
EPS15Band4|4 C71.00infobox
EPS15Bgeeendothelial cell1.00infobox
EPS15Bgeesperm1.00infobox
EPS15Bgeeinternal globus pallidus1.00infobox
EPS15Bgeefrontal pole1.00infobox
EPS15BgeeBrodmann area 231.00infobox
EPS15Bgeemiddle temporal gyrus1.00infobox
EPS15Bgeepars compacta1.00infobox
EPS15Bgeelateral nuclear group of thalamus1.00infobox
EPS15Bgeecorpus callosum1.00infobox
EPS15Bgeepons1.00infobox
EPS15BgeeRegion I of hippocampus proper1.00infobox
EPS15Bgeesubstantia nigra1.00infobox
EPS15Bgeecingulate gyrus1.00infobox
EPS15Bgeesciatic nerve1.00infobox
EPS15Bgeeventral tegmental area1.00infobox
EPS15Bgeedeep cerebellar nuclei1.00infobox
EPS15Bgeelateral geniculate nucleus1.00infobox
EPS15Bgeecerebellar vermis1.00infobox
EPS15Bgeepontine nuclei1.00infobox
EPS15Bgeelobe of cerebellum1.00infobox
EPS15BioGPSMore reference expression data1.00infobox
EPS15Chr.Chromosome 1 (human)1.00infobox
EPS15Chr.Chromosome 4 (mouse)1.00infobox
EPS15DatabasesNCBI: entry; OMA: entry1.00infobox
EPS15End51,519,266 bp1.00infobox
EPS15End109,245,014 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around EPS15 bring nearby vocabulary together. In this analysis, examples include Factor, Growth and Receptor. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • EPS15
    • Factor
    • Growth
    • Receptor
    • Function
    • Pathway
    • Search
    • Substrate
    • Gene
    • Location
    • Protein
    • Chromosome
    • Human
  • eps15
    • Factor
    • Growth
    • Receptor
    • Function
    • Pathway
    • Search
    • Substrate
    • Gene
    • Location
    • Protein
    • Chromosome
    • Human
  • gene
    • Growth
    • Location
    • Receptor
    • Chromosome
    • Human
    • Bp
    • Chr
    • End
    • Function
    • Mouse
    • Pathway
    • Search
  • function
    • Pathway
    • Search
    • Growth
    • Location
    • Receptor
    • Chromosome
    • Human
    • Interactions
    • Reading
    • References
    • Bp
    • Chr
  • protein
    • Clathrin-coated
    • Endocytosis
    • Receptor-mediated
    • Receptor
    • Humans
    • End
    • Function
    • Mouse
    • Pathway
    • Search
    • Substrate
    • Location
  • interactions
    • Reading
    • References
    • Pathway
    • Search
    • Substrate
    • Location
    • Receptor
    • Human

Connections between topic areas Semantic bridges

For EPS15, one of the stronger structural bridges in this analysis connects EPS15 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
EPS15Interactions · splits 6 ⟂ 7
EPS15Overview · splits 10 ⟂ 3

Map overview Semantic statistics

EPS15

Nodes13
Edges12
Triples110
Avg. degree1.85
Density0.153846
Components1

Source & methodology

TTTA analyzes the structure around EPS15 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — EPS15 · EN edition · Analysis: TopicsToTalkAbout

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