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ENTPD1: Clinical significance & Function

Ectonucleoside triphosphate diphosphohydrolase-1 (gene: ENTPD1; protein: NTPDase1) also known as CD39 (Cluster of Differentiation 39), is a typical cell surface enzyme with a catalytic site on the extracellular face.

Language: English [EN]
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ENTPD1 topic overview

The analysis highlights Clinical significance and Function as prominent areas in the source structure around ENTPD1.

Related topics
11
Source areas
2
Connected nodes
13
Extracted relationships
80
Concept neighborhoods
8
Bridge connections
13

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Clinical significance · 7 topics
Function · 4 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3.6.1.5
Aliases
ENTPD1, ATPDase, CD39, NTPDase-1, SPG64, ectonucleoside triphosphate diphosphohydrolase 1
Band
10q24.1 · 19 C3|19 34.25 cM
Bgee
saphenous vein · monocyte · popliteal artery · tibial arteries · tendon of biceps brachii
BioGPS
More reference expression data
Chr.
Chromosome 10 (human) · Chromosome 19 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Function

Clinical significance

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How ENTPD1 connects Entity context

The extracted context around ENTPD1 shows recurring relationship patterns in the source. For example, ENTPD1 → aortic valve, appendix, ascending aorta, atrioventricular valve, blood, carotid body, conjunctival fornix, gallbladder, granulocyte, lens, monocyte, popliteal artery, right coronary artery, saphenous vein, spermatid, spermatocyte, stroma of bone marrow, tendon of biceps brachii, tibial arteries, urethra Another extracted example is ENTPD1 → ATP binding, blood coagulation, cell adhesion, extracellular exosome, hydrolase activity, integral component of membrane, integral component of plasma membrane, membrane, nucleobase-containing small molecule catabolic process, nucleoside-diphosphatase activity, nucleoside-triphosphatase activity, nucleotide binding, plasma membrane, protein binding. Use these groups to spot repeated connection types before inspecting the individual relationships.

ENTPD1

Top relations

Bgee · 20
ENTPD1 → aortic valve, appendix, ascending aorta, atrioventricular valve, blood, carotid body, conjunctival fornix, gallbladder, granulocyte, lens, monocyte, popliteal artery, right coronary artery, saphenous vein, spermatid, spermatocyte, stroma of bone marrow, tendon of biceps brachii, tibial arteries, urethra
RNA expression pattern · 20
ENTPD1 → aortic valve, appendix, ascending aorta, atrioventricular valve, blood, carotid body, conjunctival fornix, gallbladder, granulocyte, lens, monocyte, popliteal artery, right coronary artery, saphenous vein, spermatid, spermatocyte, stroma of bone marrow, tendon of biceps brachii, tibial arteries, urethra
Gene ontology · 14
ENTPD1 → ATP binding, blood coagulation, cell adhesion, extracellular exosome, hydrolase activity, integral component of membrane, integral component of plasma membrane, membrane, nucleobase-containing small molecule catabolic process, nucleoside-diphosphatase activity, nucleoside-triphosphatase activity, nucleotide binding, plasma membrane, protein binding
related to External links · 3
ENTPD1 → Medicine Medical Subject Headings, MeSH, National Library
Band · 2
ENTPD1 → 10q24.1, 19 C3|19 34.25 cM
Chr. · 2
ENTPD1 → Chromosome 10 (human), Chromosome 19 (mouse)
End · 2
ENTPD1 → 40,730,046 bp, 95,877,266 bp
3.6.1.5 · 1
ENTPD1 → ↗
Aliases · 1
ENTPD1 → ENTPD1, ATPDase, CD39, NTPDase-1, SPG64, ectonucleoside triphosphate diphosphohydrolase 1
BioGPS · 1
ENTPD1 → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp cd39 human chr band cd73 gene chromosome 10 atp adenosine ntpdase1 activity protein location also mouse spg64 ectonucleoside triphosphate

ENTPD1 relationships Subject–Predicate–Object triples

TTTA extracted 80 structured relationships around ENTPD1. Examples in this analysis include ENTPD1 → 3.6.1.5 → ↗ and ENTPD1 → Aliases → ENTPD1, ATPDase, CD39, NTPDase-1, SPG64, ectonucleoside triphosphate diphosphohydrolase 1. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
ENTPD13.6.1.51.00infobox
ENTPD1AliasesENTPD1, ATPDase, CD39, NTPDase-1, SPG64, ectonucleoside triphosphate diphosphohydrolase 11.00infobox
ENTPD1Band10q24.11.00infobox
ENTPD1Band19 C3|19 34.25 cM1.00infobox
ENTPD1Bgeesaphenous vein1.00infobox
ENTPD1Bgeemonocyte1.00infobox
ENTPD1Bgeepopliteal artery1.00infobox
ENTPD1Bgeetibial arteries1.00infobox
ENTPD1Bgeetendon of biceps brachii1.00infobox
ENTPD1Bgeegallbladder1.00infobox
ENTPD1Bgeeright coronary artery1.00infobox
ENTPD1Bgeeurethra1.00infobox
ENTPD1Bgeeblood1.00infobox
ENTPD1Bgeeappendix1.00infobox
ENTPD1Bgeeascending aorta1.00infobox
ENTPD1Bgeeaortic valve1.00infobox
ENTPD1Bgeegranulocyte1.00infobox
ENTPD1Bgeespermatocyte1.00infobox
ENTPD1Bgeespermatid1.00infobox
ENTPD1Bgeeatrioventricular valve1.00infobox
ENTPD1Bgeelens1.00infobox
ENTPD1Bgeestroma of bone marrow1.00infobox
ENTPD1Bgeeconjunctival fornix1.00infobox
ENTPD1Bgeecarotid body1.00infobox
ENTPD1BioGPSMore reference expression data1.00infobox
ENTPD1Chr.Chromosome 10 (human)1.00infobox
ENTPD1Chr.Chromosome 19 (mouse)1.00infobox
ENTPD1DatabasesNCBI: entry; OMA: entry1.00infobox
ENTPD1End95,877,266 bp1.00infobox
ENTPD1End40,730,046 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around ENTPD1 bring nearby vocabulary together. In this analysis, examples include Protein, Gene and Human. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • atp
    • Adp
    • Adenosine
    • Ntpdase1
    • Cd73
    • Cd39
    • C3
    • Cell
    • End
    • Extracellular
    • Function
    • Mouse
    • Location
  • ENTPD1
    • Protein
    • Gene
    • Human
    • Enzyme
    • Extracellular
    • Function
    • Triphosphate
    • Location
    • Spg64
    • Activity
    • Chromosome
    • Ntpdase1
  • entpd1
    • Protein
    • Gene
    • Human
    • Enzyme
    • Extracellular
    • Function
    • Triphosphate
    • Location
    • Spg64
    • Activity
    • Chromosome
    • Ntpdase1
  • function
    • Location
    • Activity
    • Chromosome
    • Gene
    • Bp
    • Chr
    • Human
    • C3
    • End
    • Mouse
    • Triphosphate
    • Protein
  • adp
    • Atp
    • Adenosine
    • Ntpdase1
    • Cd73
    • Cd39
  • adenosine
    • Cd73
    • Pathway
    • Cd39
    • Atp
    • Adp
  • adenosine monophosphate
    • Cd73
    • Pathway
    • Cd39
    • Atp
    • Adp
  • cd73
    • Pathway

Connections between topic areas Semantic bridges

For ENTPD1, one of the stronger structural bridges in this analysis connects ENTPD1 with Clinical significance. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
ENTPD1Clinical significance · splits 6 ⟂ 8
ENTPD1Function · splits 9 ⟂ 5

Map overview Semantic statistics

ENTPD1

Nodes14
Edges13
Triples80
Avg. degree1.86
Density0.142857
Components1

Source & methodology

TTTA analyzes the structure around ENTPD1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Clinical significance & Function, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — ENTPD1 · EN edition · Analysis: TopicsToTalkAbout

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