Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

Dual oxidase 2

Dual oxidase 2, also known as DUOX2 or ThOX2 (for thyroid oxidase), is an enzyme that in humans is encoded by the DUOX2 gene. Dual oxidase is an enzyme that was first identified in the mammalian thyroid gland. In humans, two isoforms are found; hDUOX1 and hDUOX2 (this enzyme). The protein location is not exclusive to thyroid tissue; hDUOX1 is prominent…

Standards, Function & Overview

Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Research this topic

Explore the main themes, entities and connections around Dual oxidase 2. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Explore this topic

Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.

Function

ROSPhagocyticNADPH oxidaseNOX2NOX1
14 related topics

Overview

ThyroidOxidaseEnzymeGeneThyroid gland
6 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

1.6.3.1
↗
Aliases
DUOX2, LNOX2, NOXEF2, P138-TOX, TDH6, THOX2, dual oxidase 2
Band
15q21.1 · 2|2 E5
Bgee
gallbladder · nasal epithelium · palpebral conjunctiva · right lobe of thyroid gland · left lobe of thyroid gland
BioGPS
More reference expression data
Chr.
Chromosome 15 (human) · Chromosome 2 (mouse)

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Function

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Dual oxidase 2

Nodes23
Edges22
Triples104
Avg. degree1.91
Density0.086957
Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

Dual oxidase 2

Top relations

Gene ontology · 42
Dual oxidase 2 → adenohypophysis morphogenesis, apical part of cell, apical plasma membrane, bone mineralization, calcium ion binding, cell junction, cell leading edge, cell surface, cellular oxidant detoxification, cuticle development, cytokine-mediated signaling pathway, cytosol, defense response, endoplasmic reticulum, extracellular exosome, fertilization, heme binding, hormone biosynthetic process, hormone metabolic process, hydrogen peroxide biosynthetic process
Bgee · 20
Dual oxidase 2 → appendix, colon, duodenum, embryo, esophagus, gallbladder, gastric mucosa, ileum, islet of Langerhans, jejunum, left lobe of thyroid gland, mouth, nasal epithelium, palpebral conjunctiva, pancreas, pancreatic epithelial cell, right lobe of thyroid gland, sperm, stomach, urinary bladder
RNA expression pattern · 20
Dual oxidase 2 → appendix, colon, duodenum, embryo, esophagus, gallbladder, gastric mucosa, ileum, islet of Langerhans, jejunum, left lobe of thyroid gland, mouth, nasal epithelium, palpebral conjunctiva, pancreas, pancreatic epithelial cell, right lobe of thyroid gland, sperm, stomach, urinary bladder
Band · 2
Dual oxidase 2 → 15q21.1, 2|2 E5
Chr. · 2
Dual oxidase 2 → Chromosome 15 (human), Chromosome 2 (mouse)
End · 2
Dual oxidase 2 → 122,128,930 bp, 45,114,172 bp
1.6.3.1 · 1
Dual oxidase 2 → ↗
Aliases · 1
Dual oxidase 2 → DUOX2, LNOX2, NOXEF2, P138-TOX, TDH6, THOX2, dual oxidase 2
BioGPS · 1
Dual oxidase 2 → More reference expression data
Databases · 1
Dual oxidase 2 → NCBI: entry; OMA: entry

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

thyroid oxidase bp enzyme human gene duox2 dual chr band location duox chromosome 15 hduox1 species protein function nox known

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Dual oxidase 21.6.3.1↗1.00infobox
Dual oxidase 2AliasesDUOX2, LNOX2, NOXEF2, P138-TOX, TDH6, THOX2, dual oxidase 21.00infobox
Dual oxidase 2Band15q21.11.00infobox
Dual oxidase 2Band2|2 E51.00infobox
Dual oxidase 2Bgeegallbladder1.00infobox
Dual oxidase 2Bgeenasal epithelium1.00infobox
Dual oxidase 2Bgeepalpebral conjunctiva1.00infobox
Dual oxidase 2Bgeeright lobe of thyroid gland1.00infobox
Dual oxidase 2Bgeeleft lobe of thyroid gland1.00infobox
Dual oxidase 2Bgeegastric mucosa1.00infobox
Dual oxidase 2Bgeeislet of Langerhans1.00infobox
Dual oxidase 2Bgeeappendix1.00infobox
Dual oxidase 2Bgeesperm1.00infobox
Dual oxidase 2Bgeepancreatic epithelial cell1.00infobox
Dual oxidase 2Bgeeileum1.00infobox
Dual oxidase 2Bgeejejunum1.00infobox
Dual oxidase 2Bgeecolon1.00infobox
Dual oxidase 2Bgeeduodenum1.00infobox
Dual oxidase 2Bgeestomach1.00infobox
Dual oxidase 2Bgeeembryo1.00infobox
Dual oxidase 2Bgeeurinary bladder1.00infobox
Dual oxidase 2Bgeeesophagus1.00infobox
Dual oxidase 2Bgeepancreas1.00infobox
Dual oxidase 2Bgeemouth1.00infobox
Dual oxidase 2BioGPSMore reference expression data1.00infobox
Dual oxidase 2Chr.Chromosome 15 (human)1.00infobox
Dual oxidase 2Chr.Chromosome 2 (mouse)1.00infobox
Dual oxidase 2DatabasesNCBI: entry; OMA: entry1.00infobox
Dual oxidase 2End45,114,172 bp1.00infobox
Dual oxidase 2End122,128,930 bp1.00infobox

Related concept clusters Concept neighborhoods

These clusters group vocabulary that occurs around closely connected concepts in the source material.

    Connections between topic areas Semantic bridges

    Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

    Min side: 3
    For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.