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DSIF

DSIF (DRB Sensitivity Inducing Factor) is a protein complex that can either negatively or positively affect transcription by RNA polymerase II (Pol II). It can interact with the negative elongation factor (NELF) to promote the stalling of Pol II at some genes, which is called promoter proximal pausing. The pause occurs soon after initiation, once 20–60…

Role in Diseases & Overview

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Overview

Role in Diseases

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Map overview Semantic statistics

DSIF

Nodes17
Edges16
Triples4
Avg. degree1.88
Density0.117647
Components1

How this topic connects Entity context

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DSIF

Top relations

related to HIV · 4
DSIF → HIV-1, P-TEFb, Tat, This

Important terminology Word statistics

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Important terminology

elongation spt5 hspt5 factor complex ii pol bacteria transcription role hspt4 archaea rna polymerase stalling occurs humans rnap domain p-tefb

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
DSIFrelated to HIVHIV-10.60section
DSIFrelated to HIVThis0.60section
DSIFrelated to HIVP-TEFb0.60section
DSIFrelated to HIVTat0.60section

Related concept clusters Concept neighborhoods

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    Min side: 3
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