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Deoxyribonuclease I

Deoxyribonuclease I (usually called DNase I), is an endonuclease of the DNase family coded by the human gene DNASE1. DNase I is a nuclease that cleaves DNA preferentially at phosphodiester linkages adjacent to a pyrimidine nucleotide, yielding 5'-phosphate-terminated polynucleotides with a free hydroxyl group on position 3', on average producing…

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16 related topics

In genomics

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Aliases
deoxyribonuclease IAI788650DNaseIDnl1
Band
16 A1|16 2.37 cM
Bgee
parotid gland · lacrimal gland · submandibular gland · right kidney · vestibular membrane of cochlear duct
BioGPS
n/a
Chr.
Chromosome 16 (human)
Databases
NCBI: entry; OMA: entry

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In genomics

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Deoxyribonuclease I

Nodes20
Edges19
Triples52
Avg. degree1.9
Density0.1
Components1

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Deoxyribonuclease I

Top relations

Gene ontology · 16
Deoxyribonuclease I → actin binding, apoptotic process, deoxyribonuclease activity, deoxyribonuclease I activity, DNA binding, DNA catabolic process, DNA catabolic process, endonucleolytic, endonuclease activity, extracellular region, hydrolase activity, neutrophil activation involved in immune response, nuclear envelope, nuclease activity, nucleus, regulation of acute inflammatory response, regulation of neutrophil mediated cytotoxicity
Bgee · 10
Deoxyribonuclease I → human kidney, jejunum, lacrimal gland, parotid gland, proximal tubule, right kidney, stria vascularis, submandibular gland, vestibular membrane of cochlear duct, vestibular sensory epithelium
RNA expression pattern · 10
Deoxyribonuclease I → human kidney, jejunum, lacrimal gland, parotid gland, proximal tubule, right kidney, stria vascularis, submandibular gland, vestibular membrane of cochlear duct, vestibular sensory epithelium
Aliases · 1
Deoxyribonuclease I → deoxyribonuclease IAI788650DNaseIDnl1
Band · 1
Deoxyribonuclease I → 16 A1|16 2.37 cM
BioGPS · 1
Deoxyribonuclease I → n/a
Chr. · 1
Deoxyribonuclease I → Chromosome 16 (human)
Databases · 1
Deoxyribonuclease I → NCBI: entry; OMA: entry
End · 1
Deoxyribonuclease I → 3,857,888 bp
Ensembl · 1
Deoxyribonuclease I → ENSMUSG00000005980

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Important terminology

dnase dna gene protein human endonuclease actin deoxyribonuclease sequence dnase1 bp characterized chr chromosome 16 one binds form nuclease specificity

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Deoxyribonuclease IAliasesdeoxyribonuclease IAI788650DNaseIDnl11.00infobox
Deoxyribonuclease IBand16 A1|16 2.37 cM1.00infobox
Deoxyribonuclease IBgeeparotid gland1.00infobox
Deoxyribonuclease IBgeelacrimal gland1.00infobox
Deoxyribonuclease IBgeesubmandibular gland1.00infobox
Deoxyribonuclease IBgeeright kidney1.00infobox
Deoxyribonuclease IBgeevestibular membrane of cochlear duct1.00infobox
Deoxyribonuclease IBgeehuman kidney1.00infobox
Deoxyribonuclease IBgeestria vascularis1.00infobox
Deoxyribonuclease IBgeejejunum1.00infobox
Deoxyribonuclease IBgeeproximal tubule1.00infobox
Deoxyribonuclease IBgeevestibular sensory epithelium1.00infobox
Deoxyribonuclease IBioGPSn/a1.00infobox
Deoxyribonuclease IChr.Chromosome 16 (human)1.00infobox
Deoxyribonuclease IDatabasesNCBI: entry; OMA: entry1.00infobox
Deoxyribonuclease IEnd3,857,888 bp1.00infobox
Deoxyribonuclease IEnsemblENSMUSG000000059801.00infobox
Deoxyribonuclease IEntrez134191.00infobox
Deoxyribonuclease IExternal IDsGeneCards:1.00infobox
Deoxyribonuclease IGene location (Human)Gene location (Human)Chr.Chromosome 16 (human)Band16 A1|16 2.37 cMStart3,854,806 bpEnd3,857,888 bp1.00infobox
Deoxyribonuclease IGene ontologynuclease activity1.00infobox
Deoxyribonuclease IGene ontologyendonuclease activity1.00infobox
Deoxyribonuclease IGene ontologyactin binding1.00infobox
Deoxyribonuclease IGene ontologyhydrolase activity1.00infobox
Deoxyribonuclease IGene ontologydeoxyribonuclease I activity1.00infobox
Deoxyribonuclease IGene ontologydeoxyribonuclease activity1.00infobox
Deoxyribonuclease IGene ontologyDNA binding1.00infobox
Deoxyribonuclease IGene ontologyextracellular region1.00infobox
Deoxyribonuclease IGene ontologynuclear envelope1.00infobox
Deoxyribonuclease IGene ontologynucleus1.00infobox

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