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DnaC

dnaC is a prokaryotic loading factor found in Escherichia coli that complexes with the C-terminus of helicase dnaB during the initial stages of prokaryotic DNA replication, loading dnaB onto DNA and inhibiting it from unwinding double stranded DNA (dsDNA) at a replication fork. Both dnaB and dnaC associate near the dnaA bound origin for each of the…

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Chromosome
Genomic: 4.6 - 4.6 Mb
Domains
InterPro
EC number
2.7.7.7
Entrez
948864
Organism
Escherichia coli (str. K-12 substr. MG1655)
Orthologs
NCBI: entry; OMA: entry

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DnaC

Nodes8
Edges7
Triples53
Avg. degree1.75
Density0.25
Components1

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DnaC

Top relations

related to Association of dnaB-dnaC complex · 14
DnaC → AAA, Additionally, Amino, ATP, DNA, N-terminal, RecA, Since, Specifically, The, The RecA, These, This, When
related to Dissociation of dnaC and activation of dnaB · 11
DnaC → ATP, C-terminal, DNA, First, For, In, N-terminal, Once, The, These, This
related to Binding of dnaB-dnaC complex to DNA · 10
DnaC → AAA, ADP, ATP, C-terminal, DNA, For, The, These, To, When
related to Current Research · 6
DnaC → Additionally, Current, DciA, DNA, Research, Topics
Chromosome · 1
DnaC → Genomic: 4.6 - 4.6 Mb
Domains · 1
DnaC → InterPro
EC number · 1
DnaC → 2.7.7.7
Entrez · 1
DnaC → 948864
Organism · 1
DnaC → Escherichia coli (str. K-12 substr. MG1655)
Orthologs · 1
DnaC → NCBI: entry; OMA: entry

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Important terminology

dnab dna complex replication dnab-dnac atp domain helicase hydrolysis binding unwinding interactions fork ssdna escherichia coli stranded dnag structure prokaryotic

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
DnaCChromosomeGenomic: 4.6 - 4.6 Mb1.00infobox
DnaCDomainsInterPro1.00infobox
DnaCEC number2.7.7.71.00infobox
DnaCEntrez9488641.00infobox
DnaCOrganismEscherichia coli (str. K-12 substr. MG1655)1.00infobox
DnaCOrthologsNCBI: entry; OMA: entry1.00infobox
DnaCRefSeq (Prot)NP_418781.11.00infobox
DnaCSearch forSearch forStructuresSwiss-modelDomainsInterPro1.00infobox
DnaCStructuresSwiss-model1.00infobox
DnaCSymboldnaC1.00infobox
DnaCUniProtP0AEF01.00infobox
DnaCis aprokaryotic loading factor found in Escherichia coli that complexes with the C-terminus of helicase dnaB during the initial stages of prokaryotic DNA replication0.90text

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    Min side: 3
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