Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

DKK3: Regions & Overview

Dickkopf-related protein 3 is a protein in the Dickkopf family that in humans is encoded by the DKK3 gene.

Language: English [EN]
Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.
100%
More settings
100% 100% 100% 100% 100%

DKK3 topic overview

The analysis highlights Regions and Overview as prominent areas in the source structure around DKK3.

Related topics
7
Source areas
1
Connected nodes
8
Extracted relationships
77
Concept neighborhoods
8
Bridge connections
8

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 7 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
DKK3, REIC, RIG, dickkopf WNT signaling pathway inhibitor 3, CRRL
Band
11p15.3 · 7|7 F1
Bgee
endothelial cell · Brodmann area 23 · middle temporal gyrus · lateral nuclear group of thalamus · external globus pallidus
BioGPS
More reference expression data
Chr.
Chromosome 11 (human) · Chromosome 7 (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How DKK3 connects Entity context

The extracted context around DKK3 shows recurring relationship patterns in the source. For example, DKK3 → aortic valve, ascending aorta, Brodmann area 23, calvaria, ciliary body, dentate gyrus of hippocampal formation granule cell, endothelial cell, entorhinal cortex, epithelium of lens, external globus pallidus, iris, lateral nuclear group of thalamus, middle temporal gyrus, neural layer of retina, pars compacta, primary motor cortex, right auricle of heart, tendon of biceps brachii, utricle, vena cava Another extracted example is DKK3 → adrenal gland development, anatomical structure morphogenesis, co-receptor binding, extracellular negative regulation of signal transduction, extracellular region, extracellular space, multicellular organism development, negative regulation of aldosterone biosynthetic process, negative regulation of anti-Mullerian hormone signaling pathway, negative regulation of canonical Wnt signaling pathway, negative regulation of cortisol biosynthetic process, negative regulation of signaling receptor activity, negative regulation of transcription, DNA-templated, negative regulation of Wnt signaling pathway, receptor antagonist activity, regulation of transforming growth factor beta receptor signaling pathway, Wnt signaling pathway. Use these groups to spot repeated connection types before inspecting the individual relationships.

DKK3

Top relations

Bgee · 20
DKK3 → aortic valve, ascending aorta, Brodmann area 23, calvaria, ciliary body, dentate gyrus of hippocampal formation granule cell, endothelial cell, entorhinal cortex, epithelium of lens, external globus pallidus, iris, lateral nuclear group of thalamus, middle temporal gyrus, neural layer of retina, pars compacta, primary motor cortex, right auricle of heart, tendon of biceps brachii, utricle, vena cava
RNA expression pattern · 20
DKK3 → aortic valve, ascending aorta, Brodmann area 23, calvaria, ciliary body, dentate gyrus of hippocampal formation granule cell, endothelial cell, entorhinal cortex, epithelium of lens, external globus pallidus, iris, lateral nuclear group of thalamus, middle temporal gyrus, neural layer of retina, pars compacta, primary motor cortex, right auricle of heart, tendon of biceps brachii, utricle, vena cava
Gene ontology · 17
DKK3 → adrenal gland development, anatomical structure morphogenesis, co-receptor binding, extracellular negative regulation of signal transduction, extracellular region, extracellular space, multicellular organism development, negative regulation of aldosterone biosynthetic process, negative regulation of anti-Mullerian hormone signaling pathway, negative regulation of canonical Wnt signaling pathway, negative regulation of cortisol biosynthetic process, negative regulation of signaling receptor activity, negative regulation of transcription, DNA-templated, negative regulation of Wnt signaling pathway, receptor antagonist activity, regulation of transforming growth factor beta receptor signaling pathway, Wnt signaling pathway
Band · 2
DKK3 → 11p15.3, 7|7 F1
Chr. · 2
DKK3 → Chromosome 11 (human), Chromosome 7 (mouse)
End · 2
DKK3 → 111,758,264 bp, 12,009,769 bp
Aliases · 1
DKK3 → DKK3, REIC, RIG, dickkopf WNT signaling pathway inhibitor 3, CRRL
BioGPS · 1
DKK3 → More reference expression data
Databases · 1
DKK3 → NCBI: entry; OMA: entry
Ensembl · 1
DKK3 → ENSG00000050165

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene protein bp chr human band dickkopf chromosome 11 wnt signaling pathway location family mouse development expression cell function external

DKK3 relationships Subject–Predicate–Object triples

TTTA extracted 77 structured relationships around DKK3. Examples in this analysis include DKK3 → Aliases → DKK3, REIC, RIG, dickkopf WNT signaling pathway inhibitor 3, CRRL and DKK3 → Band → 11p15.3. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
DKK3AliasesDKK3, REIC, RIG, dickkopf WNT signaling pathway inhibitor 3, CRRL1.00infobox
DKK3Band11p15.31.00infobox
DKK3Band7|7 F11.00infobox
DKK3Bgeeendothelial cell1.00infobox
DKK3BgeeBrodmann area 231.00infobox
DKK3Bgeemiddle temporal gyrus1.00infobox
DKK3Bgeelateral nuclear group of thalamus1.00infobox
DKK3Bgeeexternal globus pallidus1.00infobox
DKK3Bgeeright auricle of heart1.00infobox
DKK3Bgeetendon of biceps brachii1.00infobox
DKK3Bgeeentorhinal cortex1.00infobox
DKK3Bgeepars compacta1.00infobox
DKK3Bgeevena cava1.00infobox
DKK3Bgeeepithelium of lens1.00infobox
DKK3Bgeeciliary body1.00infobox
DKK3Bgeeiris1.00infobox
DKK3Bgeeneural layer of retina1.00infobox
DKK3Bgeeaortic valve1.00infobox
DKK3Bgeecalvaria1.00infobox
DKK3Bgeeascending aorta1.00infobox
DKK3Bgeeutricle1.00infobox
DKK3Bgeedentate gyrus of hippocampal formation granule cell1.00infobox
DKK3Bgeeprimary motor cortex1.00infobox
DKK3BioGPSMore reference expression data1.00infobox
DKK3Chr.Chromosome 11 (human)1.00infobox
DKK3Chr.Chromosome 7 (mouse)1.00infobox
DKK3DatabasesNCBI: entry; OMA: entry1.00infobox
DKK3End12,009,769 bp1.00infobox
DKK3End111,758,264 bp1.00infobox
DKK3EnsemblENSG000000501651.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around DKK3 bring nearby vocabulary together. In this analysis, examples include External, Gene and Location. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • protein
    • Development
    • Pathway
    • Signaling
    • Wnt
    • Contains
    • Cysteine
    • Embryonic
    • Involved
    • Regions
    • Rich
    • Secreted
    • Two
  • DKK3
    • External
    • Gene
    • Location
    • Pathway
    • Signaling
    • Wnt
    • Chromosome
    • Human
    • Bp
    • Chr
    • Encoded
    • Humans
  • dkk3
    • External
    • Gene
    • Location
    • Pathway
    • Signaling
    • Wnt
    • Chromosome
    • Human
    • Bp
    • Chr
    • Encoded
    • Humans
  • gene
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Protein
    • Cell
    • End
    • Expression
    • External
    • Function
    • Mouse
  • dickkopf
    • Family
    • Dkk3
    • Gene
    • Dickkopf-related
    • Encoded
    • Encodes
    • Humans
    • Member
    • Protein
    • External
    • Location
    • Pathway
  • cancer cell
    • Expression
    • Function
    • Development
    • End
    • External
    • Gene
    • Mouse
    • Dkk3
    • Location
    • Pathway
    • Signaling
    • Wnt
  • cysteine
    • Embryonic
    • Involved
    • Regions
    • Rich
    • Secreted
    • Two
    • Development
    • Pathway
    • Signaling
    • Wnt
    • Protein
  • embryonic
    • Involved
    • Regions
    • Rich
    • Secreted
    • Two
    • Development
    • Pathway
    • Signaling
    • Wnt
    • Protein

Connections between topic areas Semantic bridges

Bridges highlight paths between different parts of the DKK3 map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Map overview Semantic statistics

DKK3

Nodes9
Edges8
Triples77
Avg. degree1.78
Density0.222222
Components1

Source & methodology

TTTA analyzes the structure around DKK3 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Regions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — DKK3 · EN edition · Analysis: TopicsToTalkAbout

For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.